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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1991 1
1992 5
1993 4
1994 1
1996 2
1997 1
1998 3
1999 6
2000 3
2001 5
2002 4
2003 7
2004 3
2005 5
2006 6
2007 3
2008 10
2009 2
2010 7
2011 8
2012 7
2013 3
2014 4
2015 7
2016 12
2017 17
2018 16
2019 14
2020 10
2021 3
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167 results
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Page 1
Targeted protein degradation: elements of PROTAC design.
Paiva SL, Crews CM. Paiva SL, et al. Among authors: crews cm. Curr Opin Chem Biol. 2019 Jun;50:111-119. doi: 10.1016/j.cbpa.2019.02.022. Epub 2019 Apr 17. Curr Opin Chem Biol. 2019. PMID: 31004963 Free PMC article. Review.
Targeted protein degradation: expanding the toolbox.
Schapira M, Calabrese MF, Bullock AN, Crews CM. Schapira M, et al. Among authors: crews cm. Nat Rev Drug Discov. 2019 Dec;18(12):949-963. doi: 10.1038/s41573-019-0047-y. Epub 2019 Oct 30. Nat Rev Drug Discov. 2019. PMID: 31666732
PROteolysis TArgeting Chimeras (PROTACs) - Past, present and future.
Pettersson M, Crews CM. Pettersson M, et al. Among authors: crews cm. Drug Discov Today Technol. 2019 Apr;31:15-27. doi: 10.1016/j.ddtec.2019.01.002. Epub 2019 Feb 13. Drug Discov Today Technol. 2019. PMID: 31200855 Free PMC article. Review.
Targeted protein degradation by PROTACs.
Neklesa TK, Winkler JD, Crews CM. Neklesa TK, et al. Among authors: crews cm. Pharmacol Ther. 2017 Jun;174:138-144. doi: 10.1016/j.pharmthera.2017.02.027. Epub 2017 Feb 14. Pharmacol Ther. 2017. PMID: 28223226 Review.
Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL.
Lai AC, Toure M, Hellerschmied D, Salami J, Jaime-Figueroa S, Ko E, Hines J, Crews CM. Lai AC, et al. Among authors: crews cm. Angew Chem Int Ed Engl. 2016 Jan 11;55(2):807-10. doi: 10.1002/anie.201507634. Epub 2015 Nov 23. Angew Chem Int Ed Engl. 2016. PMID: 26593377 Free PMC article.
Catalytic in vivo protein knockdown by small-molecule PROTACs.
Bondeson DP, Mares A, Smith IE, Ko E, Campos S, Miah AH, Mulholland KE, Routly N, Buckley DL, Gustafson JL, Zinn N, Grandi P, Shimamura S, Bergamini G, Faelth-Savitski M, Bantscheff M, Cox C, Gordon DA, Willard RR, Flanagan JJ, Casillas LN, Votta BJ, den Besten W, Famm K, Kruidenier L, Carter PS, Harling JD, Churcher I, Crews CM. Bondeson DP, et al. Among authors: crews cm. Nat Chem Biol. 2015 Aug;11(8):611-7. doi: 10.1038/nchembio.1858. Epub 2015 Jun 10. Nat Chem Biol. 2015. PMID: 26075522 Free PMC article.
167 results
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