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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1960 2
1961 1
1962 1
1966 1
1967 2
1968 2
1969 2
1970 3
1971 6
1972 8
1973 12
1974 9
1975 14
1976 20
1977 12
1978 16
1979 18
1980 22
1981 17
1982 19
1983 27
1984 20
1985 37
1986 36
1987 17
1988 24
1989 20
1990 26
1991 28
1992 37
1993 26
1994 31
1995 43
1996 29
1997 25
1998 34
1999 36
2000 23
2001 37
2002 26
2003 34
2004 40
2005 42
2006 54
2007 59
2008 61
2009 57
2010 70
2011 89
2012 74
2013 114
2014 113
2015 106
2016 102
2017 113
2018 98
2019 63
2020 1
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1,895 results
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Page 1
Diagnosis and classification of Crohn's disease.
Laass MW, et al. Autoimmun Rev 2014 - Review. PMID 24424189
Crohn's disease (CrD) is a chronic relapsing inflammatory bowel disease (IBD) potentially affecting any portion of the gastrointestinal tract from the mouth to the anus. ...
Crohn's disease (CrD) is a chronic relapsing inflammatory bowel disease (IBD) potentially affecting any portion of the
Update on C-reactive protein and fecal calprotectin: are they accurate measures of disease activity in Crohn's disease?
Ma C, et al. Expert Rev Gastroenterol Hepatol 2019 - Review. PMID 30791776
'Treat-to-target' paradigms in Crohn's disease (CD) directed at suppressing intestinal inflammation require accurate and reliable measures of disease activity. ...Areas covered: We review the evidence for using serum CRP and FC in distinguishing patients with CD from those with irritable bowel syndrome, categorizing disease activity among patients with an established diagnosis of CD, predicting the likelihood of treatment response, identifying asymptomatic patients in medically or surgically induced remission who are at risk for disease relapse, and as treatment targets. ...
'Treat-to-target' paradigms in Crohn's disease (CD) directed at suppressing intestinal inflammation require accurate and relia …
Measurement of Fibrosis in Crohn's Disease Strictures with Imaging and Blood Biomarkers to Inform Clinical Decisions.
Higgins PD. Dig Dis 2017 - Review. PMID 28147365
Key Messages: Delayed gadolinium enhancement of a Crohn's disease stricture on MRI can reliably identify severe fibrosis, and may be helpful in deciding which patients will require surgery. ...The presence of upstream small bowel dilation >3.5 cm or a platelet/albumin ratio >150 helps in identifying Crohn's disease patients at high risk of stricture resection in the next 2 years. ...
Key Messages: Delayed gadolinium enhancement of a Crohn's disease stricture on MRI can reliably identify severe fibrosis, and …
Possible Biomarkers in Blood for Crohn's Disease: Oxidative Stress and MicroRNAs-Current Evidences and Further Aspects to Unravel.
Moret-Tatay I, et al. Oxid Med Cell Longev 2016 - Review. PMID 26823944 Free PMC article.
Crohn's disease (CD) is an inflammatory disorder characterised by a transmural inflammation of the intestinal wall. Although the physiopathology of the disease is not yet fully understood, it is clear that the immune response plays an important role in it. ...In fact, now OxS is being considered more a potential etiological factor for Crohn's disease rather than a concomitant effect in the disease. ...
Crohn's disease (CD) is an inflammatory disorder characterised by a transmural inflammation of the intestinal wall. Although t
Heat shock protein 90 and inflammatory activity in newly onset Crohn's disease.
Grimstad T, et al. Scand J Gastroenterol 2018. PMID 30625276
MATERIALS AND METHODS: This cross-sectional study included 53 patients who were newly diagnosed with Crohn's disease. Demographic data and disease distribution were recorded, and disease activity was rated using the Simple Endoscopic Score for Crohn's Disease (SES-CD) and the Harvey Bradshaw Index (HBI). ...CONCLUSIONS: Objective measures of disease activity and inflammation in Crohn's disease - SES-CD and CRP - were closely associated with HSP90α concentrations in plasma, suggesting that HSP90α may be a biomarker of Crohn's disease....
MATERIALS AND METHODS: This cross-sectional study included 53 patients who were newly diagnosed with Crohn's disease. Demograp …
Optimal vitamin D levels in Crohn's disease: a review.
Raftery T and O'Sullivan M. Proc Nutr Soc 2015 - Review. PMID 25497215
Vitamin D deficiency is common among patients with Crohn's disease. Serum 25-hydroxyvitamin D (25(OH)D) is the best measure of an individual's vitamin D status and current cut-off ranges for sufficiency are debatable. ...Emerging evidence suggests that vitamin D may have roles in innate and adaptive immunity, in the immune-pathogenesis of Crohn's disease, prevention of Crohn's disease-related hospitalisations and surgery, in reducing disease severity and in colon cancer prevention. ...
Vitamin D deficiency is common among patients with Crohn's disease. Serum 25-hydroxyvitamin D (25(OH)D) is the best measure of …
Prognostic value of preoperative neutrophil-to-lymphocyte ratio in Crohn's disease.
Argeny S, et al. Wien Klin Wochenschr 2018. PMID 29435759 Free PMC article.
There is little data available in patients with Crohn's disease, thus the present study was conducted to correlate preoperative Neutrophil-to-lymphocyte-ratio values with disease phenotype and postoperative course. ...CONCLUSIONS: Elevated preoperative Neutrophil-to-lymphocyte-ratio in symptomatic Crohn's disease is not predictive for complications. ...
There is little data available in patients with Crohn's disease, thus the present study was conducted to correlate preoperativ …
Correlation of Paraoxonase-1 with the Severity of Crohn's Disease.
Szczeklik K, et al. Molecules 2018. PMID 30314292 Free PMC article.
Diagnostics of Crohn's disease (CD) requires noninvasive biomarkers facilitating early detection and differentiation of the disease. ...Circulating PON-1 was found to be decreased in the CD group compared to the control group (269.89 vs. 402.56 U/L, respectively), and it correlated well with the disease activity. ...
Diagnostics of Crohn's disease (CD) requires noninvasive biomarkers facilitating early detection and differentiation of the …
The role of ABO blood groups in Crohn's disease and in monitoring response to infliximab treatment.
Yu Q, et al. Blood Transfus 2016. PMID 27136434 Free PMC article.
BACKGROUND: The variation in ABO blood groups is reported to be associated with multiple diseases. Infliximab (IFX) has been widely used in the treatment of Crohn's disease (CD). ...RESULTS: In 293 patients with CD, most patients (40.6%) had blood type O (119/293). The odds ratio (OR) of CD in blood type O patients was 1.06 (95%CI: 0.6-1.86; p=0.84) compared to all other blood types. ...
BACKGROUND: The variation in ABO blood groups is reported to be associated with multiple diseases. Infliximab (IFX) has been widely u …
Peripheral blood methylation profiling of female Crohn's disease patients.
Li Yim AYF, et al. Clin Epigenetics 2016. PMID 27279921 Free PMC article.
BACKGROUND: Crohn's disease (CD) is a chronic inflammatory disorder belonging to the inflammatory bowel diseases (IBD). CD affects distinct parts of the gastrointestinal tract, leading to symptoms including diarrhea, fever, abdominal pain, weight loss, and anemia. The aim of this study was to assess whether the DNA methylome of peripheral blood cells can be associated with CD in women. METHODS: Samples were obtained from 18 female patients with histologically confirmed ileal or ileocolic CD and 25 healthy age- and gender-matched controls (mean age and standard deviation: 30.5 ± 6.5 years for both groups). ...
BACKGROUND: Crohn's disease (CD) is a chronic inflammatory disorder belonging to the inflammatory bowel diseases (IBD). CD aff …
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