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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1954 1
1955 1
1956 1
1958 1
1959 1
1960 2
1961 3
1962 4
1964 6
1965 2
1972 1
1974 4
1976 7
1979 1
1981 1
1983 2
1988 1
1990 3
1991 2
1992 8
1993 35
1994 631
1995 1330
1996 1279
1997 1304
1998 1426
1999 1499
2000 1489
2001 1541
2002 1681
2003 1693
2004 1915
2005 1913
2006 2067
2007 2247
2008 2275
2009 2273
2010 2317
2011 2564
2012 2724
2013 2875
2014 2941
2015 3014
2016 2853
2017 3007
2018 2775
2019 1017
2020 14
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46,874 results
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Page 1
The method quality of cross-over studies involved in Cochrane Systematic Reviews.
Ding H, et al. PLoS One 2015. PMID 25867772 Free PMC article.
BACKGROUND: It is possible that cross-over studies included in current systematic reviews are being inadequately assessed, because the current risk of bias tools do not consider possible biases specific to cross-over design. ...We chose a random sample of 60 CSRs and these included 139 cross-over studies. None of these CSRs undertook a risk of bias assessment specific for cross-over studies. ...
BACKGROUND: It is possible that cross-over studies included in current systematic reviews are being inadequately assessed, because the current risk of bias tools do not consider possible biases specific to cross-over design. ...We chose a random sample of 60 CSRs a …
Analysis of cross-over studies with missing data.
Rosenkranz GK. Stat Methods Med Res 2015. PMID 24501227
This paper addresses some aspects of the analysis of cross-over trials with missing or incomplete data. A literature review on the topic reveals that many proposals provide correct results under the missing completely at random assumption while only some consider the more general missing at random situation. ...
This paper addresses some aspects of the analysis of cross-over trials with missing or incomplete data. A literature review on the topic reveals that many proposals provide correct results under the missing completely at random assumption while only some consider the more general missi …
Power to detect clinically relevant carry-over in a series of cross-over studies.
Putt ME. Stat Med 2006. PMID 16220475
In cross-over studies, carry-over is the lingering effect of a treatment into the subsequent period. Carry-over effects are differences in the extent of the carry-over between the treatments under consideration. ...Our results suggest that for two-treatment, two-period cross-over studies the power to detect clinically relevant carry-over effects is often less than 15 per cent, and the number of studies needed to differentiate this effect from the type I error rate of 10 per cent is prohibitive. ...
In cross-over studies, carry-over is the lingering effect of a treatment into the subsequent period. Carry-over effects are differences in the extent of the carry-over between the treatments under consideration. ...Our results suggest that for two-treatment, …
Authors' Response
Nystrom NA and Freeman MD. Pain Med 2018. PMID 29228276
The "optional cross-over design" for randomized controlled trials.
Ernst E and Resch KL. Fundam Clin Pharmacol 1995. PMID 8617415
At its end the patient may choose to change to the other treatment arm, if therapy was felt to be unsuccessful (= optional cross-over). In phase II, treatment continues as in phase I except for those patients who have chosen the "optional cross-over". Further cross-over points may ensue depending on the particularities of the situation, however, two such options may be adequate for most studies. ...
At its end the patient may choose to change to the other treatment arm, if therapy was felt to be unsuccessful (= optional cross-over). In phase II, treatment continues as in phase I except for those patients who have chosen the "optional cross-over". Further cross
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