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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1781 37
1782 18
1783 22
1784 27
1785 43
1786 60
1787 43
1788 33
1789 32
1790 44
1791 19
1792 33
1793 17
1794 18
1795 13
1796 14
1797 59
1798 15
1799 291
1800 377
1801 360
1802 283
1803 269
1804 289
1805 314
1806 282
1807 295
1808 289
1809 265
1810 267
1811 322
1812 238
1813 265
1814 285
1815 222
1816 315
1817 288
1818 303
1819 225
1820 213
1821 270
1822 247
1823 291
1824 269
1825 262
1826 385
1827 326
1828 467
1829 645
1830 569
1831 627
1832 313
1833 293
1834 287
1835 305
1836 271
1837 350
1838 484
1839 546
1840 695
1841 1154
1842 1487
1843 1118
1844 1248
1845 1277
1846 1404
1847 1367
1848 1203
1849 1207
1850 1125
1851 1228
1852 1309
1853 1558
1854 1306
1855 1586
1856 1587
1857 1488
1858 1541
1859 1562
1860 1632
1861 1275
1862 1112
1863 995
1864 1138
1865 1151
1866 1477
1867 1723
1868 1813
1869 1909
1870 1809
1871 2238
1872 2242
1873 2313
1874 2508
1875 2402
1876 2095
1877 2179
1878 2454
1879 2399
1880 2646
1881 3149
1882 2742
1883 3126
1884 3049
1885 3337
1886 3291
1887 3965
1888 4002
1889 4194
1890 4024
1891 3607
1892 4080
1893 4369
1894 3801
1895 4129
1896 4412
1897 4688
1898 4631
1899 4169
1900 3785
1901 3885
1902 3967
1903 3910
1904 4059
1905 4067
1906 3872
1907 4323
1908 4459
1909 4687
1910 4799
1911 5006
1912 4906
1913 5104
1914 5135
1915 4640
1916 4543
1917 4281
1918 4567
1919 4618
1920 4960
1921 4628
1922 4123
1923 4432
1924 4850
1925 4990
1926 5342
1927 5887
1928 5479
1929 5741
1930 5630
1931 5496
1932 5546
1933 5610
1934 5507
1935 5661
1936 5384
1937 5308
1938 5765
1939 5541
1940 4998
1941 4838
1942 4775
1943 4517
1944 4745
1945 20420
1946 53735
1947 64959
1948 70704
1949 62803
1950 85750
1951 103741
1952 108052
1953 108914
1954 105914
1955 108541
1956 107005
1957 111515
1958 109456
1959 109957
1960 112134
1961 120097
1962 125629
1963 141519
1964 162086
1965 176635
1966 179739
1967 191497
1968 207843
1969 215043
1970 218959
1971 222862
1972 227494
1973 230625
1974 234509
1975 248225
1976 250214
1977 249442
1978 257748
1979 265018
1980 266741
1981 271091
1982 282647
1983 294218
1984 302138
1985 318303
1986 330749
1987 346608
1988 362917
1989 376805
1990 381506
1991 378784
1992 380230
1993 387957
1994 399421
1995 408597
1996 418444
1997 416019
1998 433516
1999 450553
2000 486856
2001 499174
2002 516981
2003 544483
2004 586427
2005 645316
2006 689907
2007 727389
2008 774118
2009 812668
2010 874546
2011 948965
2012 1014835
2013 1065377
2014 1117142
2015 1157067
2016 1189237
2017 1209805
2018 1251893
2019 1307747
2020 1488779
2021 1627247
2022 1624398
2023 1527108
2024 1230754
2025 1300

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35,208,267 results

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Gss deficiency causes age-related fertility impairment via ROS-triggered ferroptosis in the testes of mice.
Zhu H, Cheng Y, Wang X, Yang X, Liu M, Liu J, Liu S, Wang H, Zhang A, Li R, Ye C, Zhang J, Gao J, Fu X, Wu B. Zhu H, et al. Cell Death Dis. 2023 Dec 19;14(12):845. doi: 10.1038/s41419-023-06359-x. Cell Death Dis. 2023. PMID: 38114454 Free PMC article.
Glutathione synthetase (GSS) catalyzes the final step in the synthesis of glutathione (GSH), a well-established antioxidant. ...
Glutathione synthetase (GSS) catalyzes the final step in the synthesis of glutathione (GSH), a well-established antioxidant. .
Forging Ahead.
Anklesaria Z, Hunt D, Shah M, Sharpe B, Monash B. Anklesaria Z, et al. J Hosp Med. 2017 Mar;12(3):188-192. doi: 10.12788/jhm.2706. J Hosp Med. 2017. PMID: 28272598 Review.
Soluble recombinant protein production in Pseudoalteromonas haloplanktis TAC125.
Giuliani M, Parrilli E, Sannino F, Apuzzo G, Marino G, Tutino ML. Giuliani M, et al. Methods Mol Biol. 2015;1258:243-57. doi: 10.1007/978-1-4939-2205-5_13. Methods Mol Biol. 2015. PMID: 25447868 Review.
In this chapter we describe the use of Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 as host of choice for the production of the heavy-chain antibody fragment VHHD6.1. ...
In this chapter we describe the use of Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 as host of choice for the pro …
Conformational Flexibility Drives Cold Adaptation in Pseudoalteromonas haloplanktis TAC125 Globins.
Giordano D, Boubeta FM, di Prisco G, Estrin DA, Smulevich G, Viappiani C, Verde C. Giordano D, et al. Antioxid Redox Signal. 2020 Feb 20;32(6):396-411. doi: 10.1089/ars.2019.7887. Epub 2019 Nov 11. Antioxid Redox Signal. 2020. PMID: 31578873 Review.
Future Directions: In this review, we describe the studies and approaches used to investigate stability and flexibility in the cold-adapted globins of the Antarctic marine bacterium Pseudoalteromonas haloplanktis TAC125. In fact, future research directions will be p …
Future Directions: In this review, we describe the studies and approaches used to investigate stability and flexibility in the cold-adapted …
Glutathione synthetase deficiency.
Njålsson R. Njålsson R. Cell Mol Life Sci. 2005 Sep;62(17):1938-45. doi: 10.1007/s00018-005-5163-7. Cell Mol Life Sci. 2005. PMID: 15990954 Free PMC article. Review.
Glutathione (GSH), one of the most important antioxidants in the eukaryotic organism, is synthesized in a two-step procedure where the last step is catalysed by the enzyme glutathione synthetase (GSS). GSS deficiency is inherited autosomal recessively, and patients …
Glutathione (GSH), one of the most important antioxidants in the eukaryotic organism, is synthesized in a two-step procedure where the last …
The globins of cold-adapted Pseudoalteromonas haloplanktis TAC125: from the structure to the physiological functions.
Giordano D, Coppola D, Russo R, Tinajero-Trejo M, di Prisco G, Lauro F, Ascenzi P, Verde C. Giordano D, et al. Adv Microb Physiol. 2013;63:329-89. doi: 10.1016/B978-0-12-407693-8.00008-X. Adv Microb Physiol. 2013. PMID: 24054800 Review.
The availability of genomic sequences from an increasing number of cold-adapted species is providing insights to understand the molecular mechanisms underlying crucial physiological processes in polar organisms. The genome of Pseudoalteromonas haloplanktis TAC125 co …
The availability of genomic sequences from an increasing number of cold-adapted species is providing insights to understand the molecular me …
Protein Structure Analysis and Validation with X-Ray Crystallography.
Papageorgiou AC, Poudel N, Mattsson J. Papageorgiou AC, et al. Methods Mol Biol. 2021;2178:377-404. doi: 10.1007/978-1-0716-0775-6_25. Methods Mol Biol. 2021. PMID: 33128762
X-ray crystallography is the main technique for the determination of protein structures. ...Moreover, the requirement for pure, homogeneous, and stable protein solutions in crystallizations makes X-ray crystallography beneficial in other
X-ray crystallography is the main technique for the determination of protein structures. ...Moreover, the requirement f
Emerging regulatory paradigms in glutathione metabolism.
Liu Y, Hyde AS, Simpson MA, Barycki JJ. Liu Y, et al. Adv Cancer Res. 2014;122:69-101. doi: 10.1016/B978-0-12-420117-0.00002-5. Adv Cancer Res. 2014. PMID: 24974179 Free PMC article. Review.
Crystal Structure Analysis of SH2 Domains in Complex with Phosphotyrosine Peptides.
Senda M, Senda T. Senda M, et al. Methods Mol Biol. 2023;2705:39-58. doi: 10.1007/978-1-0716-3393-9_3. Methods Mol Biol. 2023. PMID: 37668968
While the number of tertiary structures solved by cryoelectron microscopy has rapidly increased, X-ray crystallography is still a popular method to determine the tertiary structure of proteins at atomic resolution. However, there are still problems associated …
While the number of tertiary structures solved by cryoelectron microscopy has rapidly increased, X-ray crystallography
Clickable Glutathione-Based Identification of Cysteine Glutathionylation.
Matarage Don NNJ, Kukulage DSK, Ahn YH. Matarage Don NNJ, et al. Curr Protoc. 2023 Oct;3(10):e907. doi: 10.1002/cpz1.907. Curr Protoc. 2023. PMID: 37818879 Free PMC article.
Clickable glutathione is a glutathione-derived chemical probe designed to identify and analyze protein S-glutathionylation, a major cysteine oxidation in redox signaling. An engineered glutathione synthetase mutant (GS M4) is used to synthesize clickable glutathione …
Clickable glutathione is a glutathione-derived chemical probe designed to identify and analyze protein S-glutathionylation, a major cysteine …
35,208,267 results
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