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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 2
1946 15
1947 26
1948 12
1949 14
1950 22
1951 14
1952 16
1953 25
1954 36
1955 22
1956 20
1957 29
1958 26
1959 18
1960 27
1961 26
1962 31
1963 33
1964 81
1965 163
1966 167
1967 208
1968 377
1969 382
1970 289
1971 419
1972 427
1973 434
1974 494
1975 392
1976 350
1977 309
1978 287
1979 376
1980 274
1981 317
1982 324
1983 343
1984 371
1985 395
1986 370
1987 387
1988 439
1989 535
1990 530
1991 578
1992 593
1993 651
1994 759
1995 620
1996 633
1997 609
1998 807
1999 1068
2000 969
2001 1289
2002 1376
2003 1530
2004 1871
2005 2335
2006 2549
2007 2852
2008 2557
2009 2710
2010 2479
2011 2598
2012 2737
2013 2445
2014 2198
2015 1745
2016 1268
2017 1052
2018 1078
2019 548
2020 10
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50,850 results
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Page 1
Protein Crystallization.
McPherson A. Methods Mol Biol 2017 - Review. PMID 28573568
Protein crystallization was discovered by chance nearly 200 years ago and was developed in the late nineteenth century as a powerful purification tool, and a demonstration of chemical purity. ...Successes in macromolecular crystallization have multiplied rapidly in recent years due to the advent of practical, easy-to-use screening kits, and the application of laboratory robotics....
Protein crystallization was discovered by chance nearly 200 years ago and was developed in the late nineteenth century as a powerful …
Introduction to protein crystallization.
McPherson A and Gavira JA. Acta Crystallogr F Struct Biol Commun 2014 - Review. PMID 24419610 Free PMC article.
Protein crystallization was discovered by chance about 150 years ago and was developed in the late 19th century as a powerful purification tool and as a demonstration of chemical purity. ...Successes in macromolecular crystallization have multiplied rapidly in recent years owing to the advent of practical, easy-to-use screening kits and the application of laboratory robotics. ...
Protein crystallization was discovered by chance about 150 years ago and was developed in the late 19th century as a powerful purific …
Computational crystallization.
Altan I, et al. Arch Biochem Biophys 2016 - Review. PMID 26792536 Free PMC article.
Prior knowledge has been used to develop tools that computationally predict the crystallization outcome and define mutational approaches that enhance the likelihood of crystallization. ...Computational analysis of crystallization requires complete and correctly formatted data. While massive crystallization screening efforts are under way, the data available from many of these studies are sparse. ...
Prior knowledge has been used to develop tools that computationally predict the crystallization outcome and define mutational approac …
Optimization of crystallization conditions for biological macromolecules.
McPherson A and Cudney B. Acta Crystallogr F Struct Biol Commun 2014 - Review. PMID 25372810 Free PMC article.
The improvement process is referred to as optimization, and it entails sequential, incremental changes in the chemical parameters that influence crystallization, such as pH, ionic strength and precipitant concentration, as well as physical parameters such as temperature, sample volume and overall methodology. ...
The improvement process is referred to as optimization, and it entails sequential, incremental changes in the chemical parameters that influ …
Current trends in protein crystallization.
Gavira JA. Arch Biochem Biophys 2016 - Review. PMID 26747744
This complexity contributes to their great sensitivity to any external change and dictate the uncertainty of crystallization. ...The low likelihood of protein crystallization is rationalized by considering the intrinsic polypeptide nature (folded state, surface charge, etc) followed by a description of the standard crystallization methods (batch, vapour diffusion and counter-diffusion), including high throughput advances. ...
This complexity contributes to their great sensitivity to any external change and dictate the uncertainty of crystallization. ...The …
Crystallization Methods for Preparation of Nanocrystals for Drug Delivery System.
Gao Y, et al. Curr Pharm Des 2015 - Review. PMID 26027573
Crystallization is the main and efficient unit operation to produce nanocrystals. Both traditional crystallization methods such as reactive crystallization, anti-solvent crystallization and new crystallization methods such as supercritical fluid crystallization, high-gravity controlled precipitation can be used to produce nanocrystals. The current mini-review outlines the main crystallization methods addressed in literature. The advantages and disadvantages of each method were summarized and compared....
Crystallization is the main and efficient unit operation to produce nanocrystals. Both traditional crystallization methods suc
Crystallization screening: the influence of history on current practice.
Luft JR, et al. Acta Crystallogr F Struct Biol Commun 2014 - Review. PMID 25005076 Free PMC article.
While crystallization historically predates crystallography, it is a critical step for the crystallographic process. The rich history of crystallization and how that history influences current practices is described. The tremendous impact of crystallization screens on the field is discussed....
While crystallization historically predates crystallography, it is a critical step for the crystallographic process. The rich history …
The use of ultrasound in the crystallization process of an active pharmaceutical ingredient.
Belca LM, et al. Ultrason Sonochem 2019. PMID 31450288
In this research, ultrasound was used in the crystallization process as an alternative to conventional spontaneous crystallization and seeding crystallization. ...Compared to spontaneous crystallization and seeding crystallization ultrasound-assisted crystallization has significantly improved fundamental crystallization parameters: nucleation, the growth of crystals and filtration time. ...
In this research, ultrasound was used in the crystallization process as an alternative to conventional spontaneous crystallization
Can the propensity of protein crystallization be increased by using systematic screening with metals?
Hegde RP, et al. Protein Sci 2017 - Review. PMID 28643473 Free PMC article.
Protein crystallization is one of the major bottlenecks in protein structure elucidation with new strategies being constantly developed to improve the chances of crystallization. ...Some examples of metal-mediated oligomerization and crystallization together with our experience on metal-mediated crystallization of a putative rRNA methyltransferase from Sinorhizobium meliloti are presented. ...
Protein crystallization is one of the major bottlenecks in protein structure elucidation with new strategies being constantly develop …
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