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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1956 1
1959 1
1960 1
1961 4
1962 55
1963 215
1964 340
1965 326
1966 370
1967 391
1968 560
1969 570
1970 613
1971 720
1972 766
1973 780
1974 839
1975 736
1976 615
1977 664
1978 656
1979 760
1980 747
1981 711
1982 713
1983 792
1984 873
1985 971
1986 922
1987 1051
1988 1295
1989 1500
1990 1725
1991 1951
1992 2067
1993 2336
1994 2053
1995 2192
1996 2268
1997 2210
1998 2300
1999 2228
2000 2373
2001 2416
2002 2553
2003 2982
2004 3354
2005 3468
2006 3765
2007 4285
2008 4740
2009 5613
2010 5414
2011 5444
2012 5732
2013 5195
2014 4800
2015 4612
2016 3862
2017 4054
2018 3734
2019 2175
2020 130
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Search Results

111,530 results
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Page 1
Oral gram-positive bacterial DNA-based identification of saliva from highly degraded samples.
Ohta J and Sakurada K. Forensic Sci Int Genet 2019. PMID 31302459
We compared saliva markers' detectability from the degraded samples-oral gram-positive bacterial DNA (Streptococcus salivarius and Streptococcus oralis), oral gram-negative bacterial DNA (Veillonella atypica and Prevotella maculosa) and salivary α-amylase. ...The forensic applicability of bacterial DNA test evaluated, using mock case samples, indicates that the oral gram-positive bacterial DNA was more resistant to degradation than the other markers. ...
We compared saliva markers' detectability from the degraded samples-oral gram-positive bacterial DNA (Streptococcus salivarius …
Human placenta has no microbiome but can contain potential pathogens
de Goffau MC, et al. Nature 2019. PMID 31367035 Free PMC article.
We sought to determine whether pre-eclampsia, spontaneous preterm birth or the delivery of infants who are small for gestational age were associated with the presence of bacterial DNA in the human placenta. ...Almost all signals were related either to the acquisition of bacteria during labour and delivery, or to contamination of laboratory reagents with bacterial DNA. ...
We sought to determine whether pre-eclampsia, spontaneous preterm birth or the delivery of infants who are small for gestational age were as …
Identification of Extracellular DNA-Binding Proteins in the Biofilm Matrix.
Kavanaugh JS, et al. mBio 2019. PMID 31239382 Free PMC article.
We developed a new approach that couples Southwestern blotting and mass spectrometry to discover proteins that bind extracellular DNA (eDNA) in bacterial biofilms. ...Extracellular DNA (eDNA) has been recognized as an EPS constituent for many bacterial species and has been shown to be important in promoting biofilm formation. ...
We developed a new approach that couples Southwestern blotting and mass spectrometry to discover proteins that bind extracellular DNA
Evaluation of Methods for the Extraction of Microbial DNA From Vaginal Swabs Used for Microbiome Studies.
Mattei V, et al. Front Cell Infect Microbiol 2019. PMID 31245304 Free PMC article.
The vaginal environment is colonized by several species of bacteria that have a major influence on reproductive health. The advancement of sequencing technologies has made the assessment of the composition of the microbiota possible through microbial DNA extraction and sequencing. ...Vaginal microbiota diversities were determined using MiSeq-Illumina high-throughput sequencing of bacterial 16S rDNA V1-V3 fingerprint. ...
The vaginal environment is colonized by several species of bacteria that have a major influence on reproductive health. The advanceme …
Cooperative DNA binding by proteins through DNA shape complementarity.
Hancock SP, et al. Nucleic Acids Res 2019. PMID 31616952 Free article.
During the site-specific DNA recombination reaction that excises phage λ from the chromosome, the bacterial DNA architectural protein Fis recruits multiple λ-encoded Xis proteins to the attR recombination site. ...Comparisons with structures of DNA complexes containing only Fis or Xis, together with mutant protein and DNA binding studies, support a mechanism for cooperative protein binding solely by DNA allostery. ...
During the site-specific DNA recombination reaction that excises phage λ from the chromosome, the bacterial DNA archite …
A quest for coordination among activities at the replisome
Kapadia N and Reyes-Lamothe R. Biochem Soc Trans 2019 - Review. PMID 31395754
Faithful DNA replication is required for transmission of the genetic material across generations. The basic mechanisms underlying this process are shared among all organisms: progressive unwinding of the long double-stranded DNA; synthesis of RNA primers; and synthesis of a new DNA chain. ...The purpose of this review is to provide an overview of the recent insights into the dynamic nature of the bacterial replisome, revealed through single-molecule techniques, and to describe some aspects of the eukaryotic replisome under this framework. ...
Faithful DNA replication is required for transmission of the genetic material across generations. The basic mechanisms underlying thi …
Sharp kinking of a coiled-coil in MutS allows DNA binding and release.
Bhairosing-Kok D, et al. Nucleic Acids Res 2019. PMID 31372631 Free PMC article.
DNA mismatch repair (MMR) corrects mismatches, small insertions and deletions in DNA during DNA replication. While scanning for mismatches, dimers of MutS embrace the DNA helix with their lever and clamp domains. ...The mutants made to disrupt the helical fold at the kink site diminish DNA binding, whereas those made to increase stability of coiled-coil result in stronger DNA binding. ...
DNA mismatch repair (MMR) corrects mismatches, small insertions and deletions in DNA during DNA replication. While scan
DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenes.
Nye TM, et al. PLoS Pathog 2019. PMID 31206562 Free PMC article.
DNA methylation is pervasive across all domains of life. In bacteria, the presence of N6-methyladenosine (m6A) has been detected among diverse species, yet the contribution of m6A to the regulation of gene expression is unclear in many organisms. ...These results demonstrate that, in addition to restriction of foreign DNA, gram-positive bacteria also use restriction modification systems to regulate the expression of gene networks important for virulence....
DNA methylation is pervasive across all domains of life. In bacteria, the presence of N6-methyladenosine (m6A) has been detect
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