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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1964 1
1974 1
1977 1
1978 1
1979 1
1981 2
1982 1
1983 8
1985 3
1986 2
1987 2
1988 5
1989 1
1990 1
1991 3
1992 37
1993 1435
1994 4195
1995 4801
1996 4636
1997 4490
1998 4224
1999 4261
2000 4530
2001 4752
2002 4695
2003 4750
2004 4719
2005 3964
2006 2890
2007 2514
2008 2177
2009 1871
2010 1641
2011 1611
2012 1700
2013 1484
2014 1155
2015 1054
2016 965
2017 686
2018 486
2019 237
2020 5
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72,013 results
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Page 1
Preparation of Single-Cell RNA-Seq Libraries for Next Generation Sequencing
Trombetta JJ, et al. Curr Protoc Mol Biol 2014 - Review. PMID 24984854 Free PMC article.
Complementary DNA (cDNA) is made from full-length mRNA transcripts using a reverse transcriptase that has terminal transferase activity. ...
Complementary DNA (cDNA) is made from full-length mRNA transcripts using a reverse transcriptase that has terminal transferase
Quality control of RNA-seq experiments
Li X, et al. Methods Mol Biol 2015. PMID 25577376
Direct sequencing of the complementary DNA (cDNA) using high-throughput sequencing technologies (RNA-seq) is widely used and allows for more comprehensive understanding of the transcriptome than microarray. ...
Direct sequencing of the complementary DNA (cDNA) using high-throughput sequencing technologies (RNA-seq) is widely used and a …
Electron microscopic visualization of complementary labeled DNA with platinum-containing guanine derivative.
Loukanov A, et al. Microsc Res Tech 2016. PMID 26805035
The object of the present report is to provide a method for a visualization of DNA in TEM by complementary labeling of cytosine with guanine derivative, which contains platinum as contrast-enhanced heavy element. The stretched single-chain DNA was obtained by modifying double-stranded DNA. The labeling method comprises the following steps: (i) stretching and adsorption of DNA on the support film of an electron microscope grid (the hydrophobic carbon film holding negative charged DNA); (ii) complementary labeling of the cytosine bases from the stretched single-stranded DNA pieces on the support film with platinum containing guanine derivative to form base-specific hydrogen bond; and (iii) producing a magnified image of the base-specific labeled DNA. ...
The object of the present report is to provide a method for a visualization of DNA in TEM by complementary labeling of cytosin …
Oligomerization of Retrovirus Integrases
Grandgenett DP and Aihara H. Subcell Biochem 2018 - Review. PMID 29900499
Retrovirus integration is carried out by integrase (IN), a virus-encoded enzyme that forms an oligomeric 'intasome' complex with both ends of the linear viral DNA to catalyze their concerted insertions into the backbones of the host's DNA. ...
Retrovirus integration is carried out by integrase (IN), a virus-encoded enzyme that forms an oligomeric 'intasome' complex with both ends o …
Conformational Heterogeneity in a Fully Complementary DNA Three-Way Junction with a GC-Rich Branchpoint.
Toulmin A, et al. Biochemistry 2017. PMID 28820590 Free article.
DNA three-way junctions (3WJs) are branched structures that serve as important biological intermediates and as components in DNA nanostructures. We recently derived the global structure of a fully complementary 3WJ and found that it contained unpaired bases at the branchpoint, which is consistent with previous observations of branch flexibility and branchpoint reactivity. ...
DNA three-way junctions (3WJs) are branched structures that serve as important biological intermediates and as components in DNA
Zn2+ blocks annealing of complementary single-stranded DNA in a sequence-selective manner.
Lu S. Sci Rep 2014. PMID 24965053 Free PMC article.
Intranuclear free Zn(2+) sparks caused by reactive oxygen species have been observed in eukaryotic cells, but question if these free Zn(2+) outrages could have affected annealing of complementary single-stranded (ss) DNA, a crucial step in DNA synthesis, repair and recombination, has never been raised. ...Specifically, it is shown that Zn(2+) does not block annealing of repetitive DNA sequences lacking CG/GC sites that are the major components of junk DNA. ...
Intranuclear free Zn(2+) sparks caused by reactive oxygen species have been observed in eukaryotic cells, but question if these free Zn(2+) …
A fluorescent 3,7-bis-(naphthalen-1-ylethynylated)-2'-deoxyadenosine analogue reports thymidine in complementary DNA by a large emission Stokes shift.
Yanagi M, et al. Org Biomol Chem 2018. PMID 29417128
Thus, 3n7nzA (1) has the potential for use as a fluorescent probe for structural studies of DNAs/RNAs including the detection of single-base alterations in target DNA sequences....
Thus, 3n7nzA (1) has the potential for use as a fluorescent probe for structural studies of DNAs/RNAs including the detection of single-base …
72,013 results
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