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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1964 1
1974 1
1977 1
1978 1
1979 1
1981 2
1982 1
1983 8
1985 3
1986 2
1987 2
1988 5
1989 1
1990 1
1991 3
1992 37
1993 1435
1994 4195
1995 4801
1996 4636
1997 4490
1998 4224
1999 4261
2000 4530
2001 4752
2002 4695
2003 4750
2004 4719
2005 3964
2006 2890
2007 2514
2008 2177
2009 1871
2010 1641
2011 1611
2012 1700
2013 1484
2014 1155
2015 1054
2016 965
2017 686
2018 486
2019 237
2020 5
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72,013 results
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Page 1
Somatic APP gene recombination in Alzheimer's disease and normal neurons
Lee MH, et al. Nature 2018. PMID 30464338 Free PMC article.
DNA in situ hybridization identified gencDNAs within single neurons that were distinct from wild-type loci and absent from non-neuronal cells. Mechanistic studies supported neuronal 'retro-insertion' of RNA to produce gencDNAs; this process involved transcription, DNA breaks, reverse transcriptase activity, and age. ...
DNA in situ hybridization identified gencDNAs within single neurons that were distinct from wild-type loci and absent from non-neuron
TOP2B: The First Thirty Years
Austin CA, et al. Int J Mol Sci 2018 - Review. PMID 30223465 Free PMC article.
Type II DNA topoisomerases (EC 5.99.1.3) are enzymes that catalyse topological changes in DNA in an ATP dependent manner. Strand passage reactions involve passing one double stranded DNA duplex (transported helix) through a transient enzyme-bridged break in another (gated helix). ...Here we review the research on DNA topoisomerase IIβ over the 30 years since its discovery....
Type II DNA topoisomerases (EC 5.99.1.3) are enzymes that catalyse topological changes in DNA in an ATP dependent manner. Stra …
The Future of Cross-Linking and Immunoprecipitation (CLIP)
Ule J, et al. Cold Spring Harb Perspect Biol 2018 - Review. PMID 30068528 Free PMC article.
Cross-linking and immunoprecipitation (CLIP) serves this purpose by exploiting covalent protein-RNA cross-linking and RNA fragmentation, along with a series of stringent purification and quality control steps to prepare complementary DNA (cDNA) libraries for sequencing. ...
Cross-linking and immunoprecipitation (CLIP) serves this purpose by exploiting covalent protein-RNA cross-linking and RNA fragmentation, alo …
Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer.
Nong J, et al. Nat Commun 2018. PMID 30082701 Free PMC article.
SCLC is characterized by early hematogenous spread, which makes circulating cell-free tumor DNA (ctDNA) sequencing a promising modality for genomic profiling. ...Pre- and post-treatment ctDNA mutational analysis demonstrate that mutations of DNA repair and NOTCH signaling pathways are enriched in post-treatment samples. ...
SCLC is characterized by early hematogenous spread, which makes circulating cell-free tumor DNA (ctDNA) sequencing a promising modali …
Novel codons in rat Pdx-1 complementary DNA.
Kiba T. BMC Res Notes 2018. PMID 30314444 Free PMC article.
To transfect the expression vectors of Pdx-1 in the mammalian cells, the complementary DNA (cDNA) of Pdx-1 was conducted. RESULTS: Novel codons and amino acids sequences were detected in rat Pdx-1 cDNA. ...
To transfect the expression vectors of Pdx-1 in the mammalian cells, the complementary DNA (cDNA) of Pdx-1 was conducted. RESU …
The three Endonuclease III variants of Deinococcus radiodurans possess distinct and complementary DNA repair activities.
Sarre A, et al. DNA Repair (Amst) 2019. PMID 30959406 Free article.
Endonuclease III (EndoIII) is a bifunctional DNA glycosylase that removes oxidized pyrimidines from DNA. The genome of Deinococcus radiodurans encodes for an unusually high number of DNA glycosylases, including three EndoIII enzymes (drEndoIII1-3). ...Overall, these findings reveal that D. radiodurans possesses a unique set of DNA repair enzymes, including three non-redundant EndoIII variants with distinct properties and complementary activities, which together contribute to genome maintenance in this bacterium....
Endonuclease III (EndoIII) is a bifunctional DNA glycosylase that removes oxidized pyrimidines from DNA. The genome of Deinoco …
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