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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 2
1957 3
1958 3
1959 41
1960 149
1961 175
1962 144
1964 1
1966 16
1967 23
1968 45
1969 46
1970 57
1971 79
1972 65
1973 44
1974 59
1975 22
1976 13
1977 29
1978 28
1979 36
1980 38
1981 29
1982 27
1983 46
1984 59
1985 55
1986 60
1987 61
1988 60
1989 89
1990 562
1991 1452
1992 1543
1993 2157
1994 2460
1995 2643
1996 2308
1997 2520
1998 2994
1999 3313
2000 3787
2001 4123
2002 3873
2003 4682
2004 5757
2005 5448
2006 5738
2007 5970
2008 5693
2009 6026
2010 6437
2011 6866
2012 7331
2013 6799
2014 6630
2015 6064
2016 4817
2017 4243
2018 3795
2019 1994
2020 46
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118,580 results
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Page 1
DNA Origami: Scaffolds for Creating Higher Order Structures.
Hong F, et al. Chem Rev 2017 - Review. PMID 28605177
DNA has become one of the most extensively used molecular building blocks for engineering self-assembling materials. DNA origami is a technique that uses hundreds of short DNA oligonucleotides, called staple strands, to fold a long single-stranded DNA, which is called a scaffold strand, into various designer nanoscale architectures. ...These capabilities open up opportunities for a broad range of applications in chemistry, biology, physics, material science, and computer science that have often required programmed spatial control of molecules and atoms in three-dimensional (3D) space. ...
DNA has become one of the most extensively used molecular building blocks for engineering self-assembling materials. DNA origa
Interplay between DNA sequence and negative superhelicity drives R-loop structures.
Stolz R, et al. Proc Natl Acad Sci U S A 2019. PMID 30850542 Free PMC article.
To investigate this, we developed a statistical mechanical equilibrium model of R-loop formation in superhelical DNA. In this model, the energy involved in forming an R-loop includes four terms-junctional and base-pairing energies and energies associated with superhelicity and with the torsional winding of the displaced DNA single strand around the RNA:DNA hybrid. ...First, base-pairing energy can favor RNA:DNA over DNA:DNA duplexes in favorable sequences. Second, R-loops, by absorbing negative superhelicity, partially or fully relax the rest of the DNA domain, thereby returning it to a lower energy state. ...
To investigate this, we developed a statistical mechanical equilibrium model of R-loop formation in superhelical DNA. In this model, …
Surface-Guided Chemical Processes on Self-Assembled DNA Nanostructures.
Wang ZG, et al. Langmuir 2018 - Review. PMID 29884022
In this review, we discuss the surface addressability, morphological features, and charged properties of DNA nanostructures as well as the recognition, catalytic, and dynamic properties of DNA molecules. We highlight the synergies between the surface properties of DNA nanostructures and the molecular features of DNA strands, which is a key to the synthesis of conductive polymer nanomaterials with well-defined shapes or electronic/optical properties. ...
In this review, we discuss the surface addressability, morphological features, and charged properties of DNA nanostructures as well a …
Advances in Synthesis and Measurement of Charge Transport in DNA-Based Derivatives.
Zhuravel R, et al. Adv Mater 2018 - Review. PMID 29984432
For molecular electronics, DNA derivatives are by far more promising than native DNA due to their improved charge-transport properties. ...The derivatives include double stranded poly(G)-poly(C) DNA molecules, four stranded G4-DNA, metal-DNA hybrid molecular wires, and other DNA molecules that are modified either at the bases or at the backbone. ...
For molecular electronics, DNA derivatives are by far more promising than native DNA due to their improved charge-transport pr …
Quantitative disclosure of DNA knot chirality by high-resolution 2D-gel electrophoresis.
Valdés A, et al. Nucleic Acids Res 2019. PMID 30649468 Free PMC article.
Since knotting, like supercoiling, makes DNA molecules more compact, DNA knot probability and knot complexity can be assessed by the electrophoretic velocity of nicked DNA circles. ...This development in DNA knot analysis may uncover valuable information toward disclosing the architecture of DNA ensembles....
Since knotting, like supercoiling, makes DNA molecules more compact, DNA knot probability and knot complexity can be assessed …
Vesicle Tubulation with Self-Assembling DNA Nanosprings.
Grome MW, et al. Angew Chem Int Ed Engl 2018. PMID 29575478 Free PMC article.
DNA-coated membrane tubules emerge from spherical vesicles when DNA-origami polymerization or high membrane-surface coverage occurs. ...The DNA-origami design and deformation conditions have substantial influence on the tubulation efficiency and tube morphology, underscoring the intricate interplay between lipid bilayers and vesicle-deforming DNA structures....
DNA-coated membrane tubules emerge from spherical vesicles when DNA-origami polymerization or high membrane-surface coverage o
DNA-templated silver nanoclusters: structural correlation and fluorescence modulation.
New SY, et al. Nanoscale 2016 - Review. PMID 27722695
Based on the up-to-date DNA-AgNCs, we aim to establish the correlation between the structure/sequence of DNA templates and emission behaviour of AgNCs. Herein, we systematically present a wide-range of DNA-AgNCs based on the structural complexity of the DNA templates, including single-stranded DNA (ssDNA), double-stranded DNA (dsDNA), triple-stranded DNA (tsDNA) and DNA nanostructures. ...
Based on the up-to-date DNA-AgNCs, we aim to establish the correlation between the structure/sequence of DNA templates and emi …
Design and Characterization of pH-Triggered DNA Nanoswitches and Nanodevices Based on DNA Triplex Structures.
Idili A and Ricci F. Methods Mol Biol 2018. PMID 29926447
Triplex DNA is becoming a very useful domain to design pH-triggered DNA nanoswitches and nanodevices. The high versatility and programmability of triplex DNA interactions allows the integration of pH-controllable modules into DNA-based reactions and self-assembly processes. Here, we describe the procedure to characterize DNA-based triplex nanoswitches and more in general pH-triggered structure-switching mechanisms. ...
Triplex DNA is becoming a very useful domain to design pH-triggered DNA nanoswitches and nanodevices. The high versatility and …
Chemistry and structural biology of DNA damage and biological consequences.
Stone MP, et al. Chem Biodivers 2011 - Review. PMID 21922653 Free PMC article.
The formation of adducts by the reaction of chemicals with DNA is a critical step for the initiation of carcinogenesis. The structural analysis of various DNA adducts reveals that conformational and chemical rearrangements and interconversions are a common theme. ...Equilibria between conformational states may modulate both DNA repair and error-prone replication past these adducts. Likewise, chemical rearrangements of initially formed DNA adducts are also modulated both by the nature of adducts and the base sequences neighboring the lesion sites. ...
The formation of adducts by the reaction of chemicals with DNA is a critical step for the initiation of carcinogenesis. The structura …
Synthetic DNA filaments: from design to applications.
Pfeifer W and Saccà B. Biol Chem 2018 - Review. PMID 29604202
In this review, we describe the progresses done in this field using DNA for the rational design of synthetic filamentous-like materials with tailored structural and physical characteristics. ...We then describe the theoretical models of polymer elasticity applied to calculate the bending strength of DNA filaments, expressed in terms of persistence length. ...
In this review, we describe the progresses done in this field using DNA for the rational design of synthetic filamentous-like materia …
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