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4,101 results

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Quoted phrase not found in phrase index: "Deficiency of bile secretion"
Page 1
Function of mast cell and bile-cholangiocarcinoma interplay in cholangiocarcinoma microenvironment.
Shi A, Liu Z, Fan Z, Li K, Liu X, Tang Y, Hu J, Li X, Shu L, Zhao L, Huang L, Zhang Z, Lv G, Zhang Z, Xu Y. Shi A, et al. Gut. 2024 Jul 11;73(8):1350-1363. doi: 10.1136/gutjnl-2023-331715. Gut. 2024. PMID: 38458750
OBJECTIVE: The correlation between cholangiocarcinoma (CCA) progression and bile is rarely studied. Here, we aimed to identify differential metabolites in benign and malignant bile ducts and elucidate the generation, function and degradation of bile metabolit …
OBJECTIVE: The correlation between cholangiocarcinoma (CCA) progression and bile is rarely studied. Here, we aimed to identify differ …
Influences of Taurine Deficiency on Bile Acids of the Bile in the Cat Model.
Miyazaki T, Sasaki SI, Toyoda A, Shirai M, Ikegami T, Matsuzaki Y, Honda A. Miyazaki T, et al. Adv Exp Med Biol. 2019;1155:35-44. doi: 10.1007/978-981-13-8023-5_4. Adv Exp Med Biol. 2019. PMID: 31468384
Present study purposed to evaluate the influence of taurine deficiency on bile acids in the cats fed taurine-lacking diet. Adult cats were fed the soybean protein-based diet with 0.15% taurine or without taurine for 30 weeks. Taurine concentration in serum and liver …
Present study purposed to evaluate the influence of taurine deficiency on bile acids in the cats fed taurine-lacking diet. Adu …
Hepatobiliary transport.
Kullak-Ublick GA, Beuers U, Paumgartner G. Kullak-Ublick GA, et al. J Hepatol. 2000;32(1 Suppl):3-18. doi: 10.1016/s0168-8278(00)80411-0. J Hepatol. 2000. PMID: 10728790 Review.
In addition, lack of specific components of bile caused by a defective transporter, as in the case of mdr2/MDR3 deficiency, unmasks the toxic potential of other components. ...Whereas the downregulation of the unidirectional sinusoidal uptake system NTCP protects th …
In addition, lack of specific components of bile caused by a defective transporter, as in the case of mdr2/MDR3 deficiency, un …
Kidney ischemia/reperfusion injury causes cholangiocytes primary cilia disruption and abnormal bile secretion.
Han YK, Lim HJ, Jang G, Jang SY, Park KM. Han YK, et al. Biochim Biophys Acta Mol Basis Dis. 2024 Aug;1870(6):167225. doi: 10.1016/j.bbadis.2024.167225. Epub 2024 May 15. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38749218 Free article.
RESULTS: KIR damaged hepatocytes and cholagiocytes, disrupted cholangiocytes primary cilia, released the disrupted ciliary fragments into the bile, and caused abnormal bile secretion. Glutathione (GSH) and H(2)S levels in the livers were significantly reduced …
RESULTS: KIR damaged hepatocytes and cholagiocytes, disrupted cholangiocytes primary cilia, released the disrupted ciliary fragments into th …
Hepatocyte aquaporin 8-mediated water transport facilitates bile dilution and prevents gallstone formation in mice.
Huo X, Yu Z, Zhao F, Chen Y, Chen P, Xing L, Qiao Y, Peng Y, Tian M, Zhou M, Wu F, Wang Y, Wang C, Tian X, Lv D, Zhang B, Shi L, Ma X, Ma T. Huo X, et al. J Hepatol. 2025 Mar;82(3):464-479. doi: 10.1016/j.jhep.2024.09.023. Epub 2024 Sep 24. J Hepatol. 2025. PMID: 39326676
BACKGROUND & AIMS: Although water channel aquaporin-8 (AQP8) has been implicated in hepatic bile formation and liver diseases associated with abnormal bile flow in human and animal studies, direct evidence of its involvement in bile secretion is st …
BACKGROUND & AIMS: Although water channel aquaporin-8 (AQP8) has been implicated in hepatic bile formation and liver diseases ass …
Effects of essential fatty acid deficiency on enterohepatic circulation of bile salts in mice.
Lukovac S, Los EL, Stellaard F, Rings EH, Verkade HJ. Lukovac S, et al. Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G520-31. doi: 10.1152/ajpgi.00091.2009. Epub 2009 Jul 16. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19608735 Free article.

EFA deficiency-enhanced bile flow and biliary bile salt secretion were associated with elevated bile salt pool size and synthesis rate (+146 and +42%, respectively, P < 0.05), despite increased ileal bile salt reabsorption (+228%, P &l

…
EFA deficiency-enhanced bile flow and biliary bile salt secretion were associated with elevated bile salt …
Enhancement of bile acid-induced biliary lipid secretion by streptozotocin in rats: role of insulin deficiency.
Villanueva GR, Herreros M, Perez-Barriocanal F, Bolaños JP, Bravo P, Marin JJ. Villanueva GR, et al. J Lab Clin Med. 1990 Apr;115(4):441-8. J Lab Clin Med. 1990. PMID: 2139093
However, the presence of supersaturated bile in diabetes is still controversial. To gain information on this point, we studied the effect of insulin deficiency on biliary secretion of bile acid, phospholipid, and cholesterol in anesthetized rats. ...Th …
However, the presence of supersaturated bile in diabetes is still controversial. To gain information on this point, we studied the ef …
Metabolism of 1,25-dihydroxyvitamin D3.
Kumar R. Kumar R. Physiol Rev. 1984 Apr;64(2):478-504. doi: 10.1152/physrev.1984.64.2.478. Physiol Rev. 1984. PMID: 6324253 Review.
In general terms the vitamin D-endocrine system tends to correct abnormalities in calcium and phosphorus homeostasis. The further metabolism of 1,25(OH)2D3 to other metabolites appears to be mainly a degradative or excretory process. ...Therefore these processes, which acc …
In general terms the vitamin D-endocrine system tends to correct abnormalities in calcium and phosphorus homeostasis. The further metabol …
Bile from the hemojuvelin-deficient mouse model of iron excess is enriched in iron and ferritin.
Prajapati M, Chiu L, Zhang JZ, Chong GS, DaSilva NA, Bartnikas TB. Prajapati M, et al. Metallomics. 2024 Oct 4;16(10):mfae043. doi: 10.1093/mtomcs/mfae043. Metallomics. 2024. PMID: 39313333 Free PMC article.
We employed mice deficient in hemojuvelin, a protein essential for hepcidin expression. Mutant mice developed bile iron and ferritin excess. ...Bile proteomes differed between female and male mice for wild-type and hemojuvelin-deficient mice, suggestin …
We employed mice deficient in hemojuvelin, a protein essential for hepcidin expression. Mutant mice developed bile iron and fe …
Dilated bile canaliculi and attenuated decrease of nerve-dependent bile secretion in connexin32-deficient mouse liver.
Temme A, Stümpel F, Söhl G, Rieber EP, Jungermann K, Willecke K, Ott T. Temme A, et al. Pflugers Arch. 2001 Sep;442(6):961-6. doi: 10.1007/s004240100623. Pflugers Arch. 2001. PMID: 11680630
Gap junctional intercellular communication in the mouse liver enhances the effects of hormonal or sympathetic stimulation of glucose release from glycogen stores. To determine whether contraction of bile canaliculi and bile secretion are dependent on the func …
Gap junctional intercellular communication in the mouse liver enhances the effects of hormonal or sympathetic stimulation of glucose release …
4,101 results