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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1964 7
1965 19
1966 9
1967 15
1968 9
1969 12
1970 7
1971 12
1972 6
1973 9
1974 4
1975 11
1976 9
1977 12
1978 7
1979 34
1980 10
1981 1
1982 14
1983 13
1984 11
1985 16
1986 17
1987 26
1988 13
1989 34
1990 20
1991 20
1992 29
1993 20
1994 28
1995 38
1996 52
1997 54
1998 81
1999 46
2000 87
2001 83
2002 94
2003 98
2004 90
2005 119
2006 128
2007 78
2008 80
2009 84
2010 100
2011 132
2012 101
2013 92
2014 84
2015 79
2016 72
2017 68
2018 59
2019 45
2020 3
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2,319 results
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Page 1
DENTAL ENAMEL FORMATION AND IMPLICATIONS FOR ORAL HEALTH AND DISEASE.
Lacruz RS, et al. Physiol Rev 2017 - Review. PMID 28468833 Free PMC article.
Dental enamel is the hardest and most mineralized tissue in extinct and extant vertebrate species and provides maximum durability that allows teeth to function as weapons and/or tools as well as for food processing. ...In this review, we examine key aspects of dental enamel formation, from its developmental genesis to the ever-increasing wealth of data on the mechanisms mediating ionic transport, as well as the clinical outcomes resulting from abnormal ameloblast function....
Dental enamel is the hardest and most mineralized tissue in extinct and extant vertebrate species and provides maximum durabil
Proteomic Mapping of Dental Enamel Matrix from Inbred Mouse Strains: Unraveling Potential New Players in Enamel.
Lima Leite A, et al. Caries Res 2018. PMID 29248934
Excessive systemic exposure to fluoride can disrupt this process and lead to a condition known as dental fluorosis. The genetic background influences the responses of mineralized tissues to fluoride, such as dental fluorosis, observed in A/J and 129P3/J mice. ...Thus, the results provide a comprehensive view of the structure and function for putative uncharacterized proteins found in the enamel matrix that could help to elucidate the mechanisms involved in enamel biomineralization and genetic susceptibility to dental fluorosis....
Excessive systemic exposure to fluoride can disrupt this process and lead to a condition known as dental fluorosis. The genetic backg …
Identification of proteins from human permanent erupted enamel.
Castiblanco GA, et al. Eur J Oral Sci 2015. PMID 26432388
Proteins from the extracellular matrix of enamel are highly specific and necessary for proper enamel formation. Most proteins are removed from the matrix by enamel proteases before complete mineralization is achieved; however, some residual protein fragments persist in the mineralized matrix of erupted enamel. ...In this study, we hypothesize that other enamel-specific proteins are also found in human permanent enamel, by analysing human erupted third molars. ...
Proteins from the extracellular matrix of enamel are highly specific and necessary for proper enamel formation. Most proteins …
Twenty years of enamel matrix derivative: the past, the present and the future.
Miron RJ, et al. J Clin Periodontol 2016 - Review. PMID 26987551
BACGROUND: On June 5th, 2015 at Europerio 8, a group of leading experts were gathered to discuss what has now been 20 years of documented evidence supporting the clinical use of enamel matrix derivative (EMD). Original experiments led by Lars Hammarström demonstrated that enamel matrix proteins could serve as key regenerative proteins capable of promoting periodontal regeneration including new cementum, with functionally oriented inserting new periodontal ligament fibres, and new alveolar bone formation. ...
BACGROUND: On June 5th, 2015 at Europerio 8, a group of leading experts were gathered to discuss what has now been 20 years of documented ev …
Periodontal plastic surgery of gingival recessions at single and multiple teeth
Cairo F. Periodontol 2000 2017 - Review. PMID 28758301
The use of coronally advanced flap, laterally sliding flap, free gingival graft, the tunnel grafting technique, barrier membranes, enamel matrix derivative, collagen matrix and acellular dermal matrix are evaluated. ...
The use of coronally advanced flap, laterally sliding flap, free gingival graft, the tunnel grafting technique, barrier membranes, enamel
Enamel biomimetics-fiction or future of dentistry.
Pandya M and Diekwisch TGH. Int J Oral Sci 2019 - Review. PMID 30610185 Free PMC article.
In the present review, we discuss five pathways toward enamel tissue engineering, (i) enamel synthesis using physico-chemical means, (ii) protein matrix-guided enamel crystal growth, (iii) enamel surface remineralization, (iv) cell-based enamel engineering, and (v) biological enamel regeneration based on de novo induction of tooth morphogenesis. ...In the present review we have summarized the state of the art in enamel tissue engineering and provided novel insights into future opportunities to regenerate this arguably most fascinating of all dental tissues....
In the present review, we discuss five pathways toward enamel tissue engineering, (i) enamel synthesis using physico-chemical …
Enamel formation genes associated with dental erosive wear.
Søvik JB, et al. Caries Res 2015. PMID 25791822
Dental erosive wear is a multifactorial condition that is greatly affected by environmental factors. So far, no study has investigated how dental erosive wear is influenced by variations in enamel formation genes. The aim of the present study was to investigate polymorphisms in genes involved in enamel formation and their influence on enamel susceptibility to dental erosion. ...
Dental erosive wear is a multifactorial condition that is greatly affected by environmental factors. So far, no study has investigate
Enamel organ proteins as targets for antibodies in celiac disease: implications for oral health.
Sóñora C, et al. Eur J Oral Sci 2016. PMID 26712243
However, the etiology of these specific enamel defects remains unknown. Based on previously reported cross-reactivity of antibodies to gliadin with the enamel proteins, amelogenin and ameloblastin, we analyzed (using immunohistochemistry) the ability of anti-gliadin IgG, produced during untreated disease, to recognize enamel organ structures. ...Strong staining of the enamel matrix and of the layer of ameloblasts was observed with serum samples from women with celiac disease; high IgG reactivity was found against both gliadin peptides and enamel matrix protein extract, but there was no IgG reactivity against tissue antigens. ...
However, the etiology of these specific enamel defects remains unknown. Based on previously reported cross-reactivity of antibodies t …
Examination of rare genetic variants in dental enamel genes: The potential role of next-generation sequencing in primary dental care.
Farrow E, et al. Orthod Craniofac Res 2019. PMID 31074140
OBJECTIVES: To examine the potential role of next-generation sequencing (NGS) and genetic testing to guide preventive care in dental enamel disorders using publicly available databases to access the frequency of deleterious alleles in AMTN, AMLEX and ENAM, associated with amelogenesis imperfecta (AI). ...A genotypic-driven diagnosis of a disorder of enamel development could impact dental care, especially in young children, including early and more frequent monitoring to prevent complications. ...
OBJECTIVES: To examine the potential role of next-generation sequencing (NGS) and genetic testing to guide preventive care in dental
[Knockdown of MSX2 gene inhibits the expression of enamel matrix proteins and the enamel mineralization in mouse ameloblasts].
Liu H, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2018. PMID 29773104 Chinese.
Objective To study the effect of muscle segment homeodomain homeobox 2 (MSX2) on the expression of enamel matrix protein and the formation of enamel. ...The knockdown of MSX2 can inhibit the expression of enamel matrix proteins and the enamel mineralization....
Objective To study the effect of muscle segment homeodomain homeobox 2 (MSX2) on the expression of enamel matrix protein and the form …
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