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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1952 3
1953 5
1954 3
1955 7
1956 9
1957 7
1958 9
1959 5
1961 3
1962 4
1963 5
1964 10
1965 5
1978 1
1979 2
1980 8
1981 34
1982 41
1983 33
1984 45
1985 47
1986 54
1987 55
1988 56
1989 55
1990 61
1991 76
1992 74
1993 61
1994 68
1995 54
1996 65
1997 67
1998 72
1999 53
2000 76
2001 70
2002 83
2003 83
2004 97
2005 118
2006 122
2007 159
2008 185
2009 200
2010 229
2011 280
2012 256
2013 325
2014 319
2015 388
2016 417
2017 427
2018 467
2019 242
2020 3
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5,155 results
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Page 1
Dextran Sulfate Sodium (DSS)-Induced Acute Colitis in the Rat.
Martin JC, et al. Methods Mol Biol 2016. PMID 26530802
Among the different animal models developed to help in understanding IBDs pathophysiological mechanisms as well as to achieve pharmacological preclinical studies, the dextran sulfate sodium (DSS)-induced colitis model is the most widely used because of its simplicity, cost-effectiveness, and similarity with human IBDs. ...
Among the different animal models developed to help in understanding IBDs pathophysiological mechanisms as well as to achieve pharmacologica …
Determination of residual dextran sulfate in protein products by SEC-HPLC.
Tazi LM and Jayawickreme S. J Chromatogr B Analyt Technol Biomed Life Sci 2016 - Review. PMID 26773880
Dextran sulfate is a polyanionic derivative of dextran, produced by esterification of dextran with chlorosulphonic acid. Dextran sulfate with an average molecular weight of 8000Da can be added to the cell culture to inhibit binding of proteins to cells, increasing cellular growth and productivity. ...The quantitation limit (LOQ) was determined to be 1.5μg/mL dextran sulfate in high concentration protein samples....
Dextran sulfate is a polyanionic derivative of dextran, produced by esterification of dextran with chlorosulphon
Chemically induced mouse models of acute and chronic intestinal inflammation
Wirtz S, et al. Nat Protoc 2017. PMID 28569761
Here we present an updated version of a protocol we published in 2007 for key models of acute and chronic forms of colitis induced by 2,4,6-trinitro-benzene sulfonic acid (TNBS), oxazolone and dextran sulfate sodium (DSS). ...
Here we present an updated version of a protocol we published in 2007 for key models of acute and chronic forms of colitis induced by 2,4,6- …
Removal of Soluble Fms-Like Tyrosine Kinase-1 by Dextran Sulfate Apheresis in Preeclampsia.
Thadhani R, et al. J Am Soc Nephrol 2016. PMID 26405111 Free PMC article.
We conducted an open pilot study to evaluate the safety and potential efficacy of therapeutic apheresis with a plasma-specific dextran sulfate column to remove circulating sFlt-1 in 11 pregnant women (20-38 years of age) with very preterm preeclampsia (23-32 weeks of gestation, systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, new onset protein/creatinine ratio >0.30 g/g, and sFlt-1/placental growth factor ratio >85). ...
We conducted an open pilot study to evaluate the safety and potential efficacy of therapeutic apheresis with a plasma-specific dextran
Dextran sodium sulfate (DSS) induces necrotizing enterocolitis-like lesions in neonatal mice.
Ginzel M, et al. PLoS One 2017. PMID 28817583 Free PMC article.
In adult mice, feeding dextran sodium sulfate (DSS) represents a well-established model for experimental inflammatory bowel disease. ...
In adult mice, feeding dextran sodium sulfate (DSS) represents a well-established model for experimental inflammatory bowel di …
Dextran sulfate inhibits acute Toxoplama gondii infection in pigs.
Kato K, et al. Parasit Vectors 2016. PMID 26956033 Free PMC article.
We previously showed that dextran sulfate (DS), especially DS10 (dextran sulfate MW 10 kDa), is effective against T. gondii infection both in vitro and in mice. ...
We previously showed that dextran sulfate (DS), especially DS10 (dextran sulfate MW 10 kDa), is effective agains …
Chitosan-dextran sulfate hydrogels as a potential carrier for probiotics.
Yucel Falco C, et al. Carbohydr Polym 2017. PMID 28606523
Physical and chemical (crosslinked with genipin) hydrogels based on chitosan and dextran sulfate were developed and characterized as novel bio-materials suitable for probiotic encapsulation. ...
Physical and chemical (crosslinked with genipin) hydrogels based on chitosan and dextran sulfate were developed and characteri …
How Dextran Sulfate Affects C1-inhibitor Activity: A Model for Polysaccharide Potentiation.
Dijk M, et al. Structure 2016. PMID 27818099 Free article.
Here we present the crystal structures of the serine protease inhibitor (serpin) domain of active C1-inhibitor by itself and in complex with dextran sulfate. Unlike previously described interactions of serpins with polysaccharides, the structures and isothermal titration calorimetry experiments together reveal that dextran sulfate binds to C1-inhibitor's F1 helix with low affinity and does not invoke an allosteric change. ...
Here we present the crystal structures of the serine protease inhibitor (serpin) domain of active C1-inhibitor by itself and in complex with …
Dextran sodium sulfate (DSS) induces colitis in mice by forming nano-lipocomplexes with medium-chain-length fatty acids in the colon.
Laroui H, et al. PLoS One 2012. PMID 22427817 Free PMC article.
Research on IBD has often used the dextran sodium sulfate (DSS)-induced colitis mouse model. DSS induces in vivo but not in vitro intestinal inflammation. In addition, no DSS-associated molecule (free glucose, sodium sulfate solution, free dextran) induces in vitro or in vivo intestinal inflammation. ...
Research on IBD has often used the dextran sodium sulfate (DSS)-induced colitis mouse model. DSS induces in vivo but not in vi …
Preparation and characterization of SDF-1α-chitosan-dextran sulfate nanoparticles.
Bader AR, et al. J Vis Exp 2015. PMID 25650558 Free PMC article.
Chitosan (CS) and dextran sulfate (DS) are charged polysaccharides (glycans), which form polyelectrolyte complex-based nanoparticles when mixed under appropriate conditions. ...In the protocol described below, SDF-1α (Stromal cell-derived factor-1α), a stem cell homing factor, is first mixed and incubated with dextran sulfate. ...
Chitosan (CS) and dextran sulfate (DS) are charged polysaccharides (glycans), which form polyelectrolyte complex-based nanopar …
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