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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 2
1946 12
1947 5
1948 16
1949 12
1950 9
1951 10
1952 13
1953 19
1954 11
1955 16
1956 8
1957 16
1958 23
1959 16
1960 17
1961 28
1962 23
1963 111
1964 244
1965 180
1966 202
1967 251
1968 262
1969 367
1970 360
1971 423
1972 443
1973 458
1974 483
1975 456
1976 372
1977 397
1978 355
1979 422
1980 354
1981 372
1982 396
1983 444
1984 488
1985 461
1986 468
1987 442
1988 386
1989 424
1990 415
1991 442
1992 392
1993 411
1994 397
1995 433
1996 362
1997 391
1998 412
1999 406
2000 396
2001 419
2002 468
2003 550
2004 582
2005 567
2006 582
2007 607
2008 641
2009 681
2010 726
2011 693
2012 766
2013 836
2014 826
2015 838
2016 800
2017 792
2018 658
2019 311
2020 2
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25,552 results
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Page 1
Dietary carbohydrates: role of quality and quantity in chronic disease.
Ludwig DS, et al. BMJ 2018 - Review. PMID 29898880 Free PMC article.
David S Ludwig and colleagues examine the links between different types of carbohydrates and health...
David S Ludwig and colleagues examine the links between different types of carbohydrates and health...
Dietary fat: From foe to friend?
Ludwig DS, et al. Science 2018 - Review. PMID 30442800
For decades, dietary advice was based on the premise that high intakes of fat cause obesity, diabetes, heart disease, and possibly cancer. ...However, some argue that the relative quantity of dietary fat and carbohydrate has little relevance to health and that focus should instead be placed on which particular fat or carbohydrate sources are consumed. ...
For decades, dietary advice was based on the premise that high intakes of fat cause obesity, diabetes, heart disease, and possibly ca …
The gut microbiota at the intersection of diet and human health
Gentile CL and Weir TL. Science 2018 - Review. PMID 30442802
Dietary nutrients are essential not only for human health but also for the health and survival of the trillions of microbes that reside within the human intestines. ...
Dietary nutrients are essential not only for human health but also for the health and survival of the trillions of microbes that resi
Carbotoxicity-Noxious Effects of Carbohydrates.
Kroemer G, et al. Cell 2018 - Review. PMID 30340032 Free PMC article.
Epidemiological and experimental evidence combined with clinical intervention trials underscore the negative impact of excessive carbohydrate uptake, as well as the beneficial effects of reducing carbs in the diet. We discuss the molecular, cellular, and neuroendocrine mechanisms that link exaggerated carbohydrate intake to disease and accelerated aging as we outline dietary and pharmacologic strategies to combat carbotoxicity....
Epidemiological and experimental evidence combined with clinical intervention trials underscore the negative impact of excessive carbohyd
The Carbohydrate-Insulin Model of Obesity: Beyond "Calories In, Calories Out".
Ludwig DS and Ebbeling CB. JAMA Intern Med 2018 - Review. PMID 29971406 Free PMC article.
According to the carbohydrate-insulin model (CIM) of obesity, recent increases in the consumption of processed, high-glycemic-load carbohydrates produce hormonal changes that promote calorie deposition in adipose tissue, exacerbate hunger, and lower energy expenditure. ...Beyond the type and amount of carbohydrate consumed, the CIM provides a conceptual framework for understanding how many dietary and nondietary exposures might alter hormones, metabolism, and adipocyte biology in ways that could predispose to obesity. ...
According to the carbohydrate-insulin model (CIM) of obesity, recent increases in the consumption of processed, high-glycemic-load …
Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis.
Seidelmann SB, et al. Lancet Public Health 2018. PMID 30122560 Free PMC article.
However, the long-term effect of carbohydrate restriction on mortality is controversial and could depend on whether dietary carbohydrate is replaced by plant-based or animal-based fat and protein. ...Low carbohydrate dietary patterns favouring animal-derived protein and fat sources, from sources such as lamb, beef, pork, and chicken, were associated with higher mortality, whereas those that favoured plant-derived protein and fat intake, from sources such as vegetables, nuts, peanut butter, and whole-grain breads, were associated with lower mortality, suggesting that the source of food notably modifies the association between carbohydrate intake and mortality. ...
However, the long-term effect of carbohydrate restriction on mortality is controversial and could depend on whether dietary
Effects of Ketone Bodies on Endurance Exercise
Sansone M, et al. Curr Sports Med Rep 2018 - Review. PMID 30531462
For this reason, using ketone esters and/or salts have been proposed to obtain nutritional ketosis without limiting carbohydrate intake. Exogenous ketones should not only represent an alternative metabolic fuel source, sparing carbohydrates, but they also may increase postexercise glycogen replenishment, decrease proteolysis, and act as metabolic modulators and signaling metabolites. ...
For this reason, using ketone esters and/or salts have been proposed to obtain nutritional ketosis without limiting carbohydrate inta …
Are excess carbohydrates the main link to diabetes & its complications in Asians?
Mohan V, et al. Indian J Med Res 2018 - Review. PMID 30666980 Free PMC article.
Dietary carbohydrates form the major source of energy in Asian diets. The carbohydrate quantity and quality play a vital function in the prevention and management of diabetes. ...This article reviews the evidence associating dietary carbohydrates to the prevalence and incidence of T2D and metabolic syndrome (MS) in control of diabetes and their role in the complications of diabetes. ...
Dietary carbohydrates form the major source of energy in Asian diets. The carbohydrate quantity and quality play a vita
Carbohydrate quality and human health: a series of systematic reviews and meta-analyses.
Reynolds A, et al. Lancet 2019. PMID 30638909
BACKGROUND: Previous systematic reviews and meta-analyses explaining the relationship between carbohydrate quality and health have usually examined a single marker and a limited number of clinical outcomes. ...The certainty of evidence for relationships between carbohydrate quality and critical outcomes was graded as moderate for dietary fibre, low to moderate for whole grains, and low to very low for dietary glycaemic index and glycaemic load. ...
BACKGROUND: Previous systematic reviews and meta-analyses explaining the relationship between carbohydrate quality and health have us …
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