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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 3
1946 18
1947 13
1948 14
1949 10
1950 17
1951 14
1952 21
1953 19
1954 24
1955 16
1956 15
1957 20
1958 26
1959 20
1960 17
1961 27
1962 77
1963 289
1964 481
1965 411
1966 325
1967 398
1968 488
1969 595
1970 613
1971 743
1972 716
1973 761
1974 779
1975 718
1976 666
1977 702
1978 724
1979 669
1980 599
1981 615
1982 658
1983 741
1984 693
1985 712
1986 725
1987 711
1988 623
1989 684
1990 766
1991 735
1992 697
1993 620
1994 597
1995 580
1996 483
1997 526
1998 605
1999 511
2000 511
2001 525
2002 587
2003 622
2004 622
2005 628
2006 640
2007 677
2008 666
2009 803
2010 844
2011 890
2012 1002
2013 1109
2014 1119
2015 1128
2016 1114
2017 1174
2018 892
2019 431
2020 6
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37,242 results
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Page 1
Prolonging healthy aging: Longevity vitamins and proteins.
Ames BN. Proc Natl Acad Sci U S A 2018 - Review. PMID 30322941 Free PMC article.
It is proposed that proteins/enzymes be classified into two classes according to their essentiality for immediate survival/reproduction and their function in long-term health: that is, survival proteins versus longevity proteins. As proposed by the triage theory, a modest deficiency of one of the nutrients/cofactors triggers a built-in rationing mechanism that favors the proteins needed for immediate survival and reproduction (survival proteins) while sacrificing those needed to protect against future damage (longevity proteins). ...
It is proposed that proteins/enzymes be classified into two classes according to their essentiality for immediate survival/rep …
Plant-Based Diets: Considerations for Environmental Impact, Protein Quality, and Exercise Performance.
Lynch H, et al. Nutrients 2018 - Review. PMID 30513704 Free PMC article.
Plant-based diets provide well-established physical and environmental health benefits. These benefits stem in part from the degree of restriction of animal-derived foods. ...However, plant-based diets typically reduce the risk of developing numerous chronic diseases over the lifespan and require fewer natural resources for production compared to meat-containing diets. ...
Plant-based diets provide well-established physical and environmental health benefits. These benefits stem in part from the degree of …
The gut microbiota at the intersection of diet and human health
Gentile CL and Weir TL. Science 2018 - Review. PMID 30442802
Dietary nutrients are essential not only for human health but also for the health and survival of the trillions of microbes that reside within the human intestines. Diet is a key component of the relationship between humans and their microbial residents; gut microbes use ingested nutrients for fundamental biological processes, and the metabolic outputs of those processes may have important impacts on human physiology. ...
Dietary nutrients are essential not only for human health but also for the health and survival of the trillions of microbes that resi
Is There a Postworkout Anabolic Window of Opportunity for Nutrient Consumption? Clearing up Controversies
Schoenfeld BJ and Aragon AA. J Orthop Sports Phys Ther 2018 - Review. PMID 30702982
From the standpoint of muscle hypertrophy, the concept of a "postworkout anabolic window of opportunity" has been proposed, whereby a limited time exists after training to optimize accretion of muscle proteins. ...Thus, the purpose of this paper is to review the current literature as to the relevance of the anabolic window of opportunity, and draw evidence-based conclusions for application into practice. ...
From the standpoint of muscle hypertrophy, the concept of a "postworkout anabolic window of opportunity" has been proposed, whereby a …
Dietary proteins and protein sources and risk of death: the Kuopio Ischaemic Heart Disease Risk Factor Study.
Virtanen HEK, et al. Am J Clin Nutr 2019. PMID 30968137
BACKGROUND: Previous studies investigating protein intake in relation to mortality have provided conflicting results. OBJECTIVE: We investigated the associations of dietary protein and protein sources with risk of disease death in the prospective, population-based Kuopio Ischaemic Heart Disease Risk Factor Study. ...We estimated protein intakes with 4-d dietary records at baseline and collected data on disease deaths from the national Causes of Death Register. ...
BACKGROUND: Previous studies investigating protein intake in relation to mortality have provided conflicting results. O …
Regulatory Immune Mechanisms in Tolerance to Food Allergy
Satitsuksanoa P, et al. Front Immunol 2018 - Review. PMID 30619299 Free PMC article.
Interestingly, some of these ingested food proteins can cause allergic immune responses, which can lead to food allergy. So far it has not been completely elucidated how these proteins become immunogenic and cause food allergies. In contrast, oral tolerance helps to prevent the pathologic reactions against different types of food antigens from animal or plant origin. ...
Interestingly, some of these ingested food proteins can cause allergic immune responses, which can lead to food allergy. So far it ha …
Food-Derived Bioactive Peptides in Human Health: Challenges and Opportunities
Chakrabarti S, et al. Nutrients 2018 - Review. PMID 30424533 Free PMC article.
These physiological functions are primarily regulated by some peptides that are encrypted in the native protein sequences. These bioactive peptides can exert health beneficial properties and thus are considered as a lead compound for the development of nutraceuticals or functional foods. ...However, the commercial application of these bioactive peptides has been delayed because of the absence of appropriate and scalable production methods, proper exploration of the mechanisms of action, high gastro-intestinal digestibility, variable absorption rate, and the lack of well-designed clinical trials to provide the substantial evidence for potential health claims. ...
These physiological functions are primarily regulated by some peptides that are encrypted in the native protein sequences. The …
Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis
Wu H, et al. J Am Soc Nephrol 2019. PMID 30510133 Free PMC article.
Our snRNA-seq protocol yielded 20-fold more podocytes compared with published scRNA-seq datasets (2.4% versus 0.12%, respectively). ...For validation, analysis of frozen day 14 UUO kidney revealed rare juxtaglomerular cells, novel activated proximal tubule and fibroblast cell states, and previously unidentified tubulointerstitial signaling pathways. ...
Our snRNA-seq protocol yielded 20-fold more podocytes compared with published scRNA-seq datasets (2.4% versus 0.12%, respectively). . …
Dietary Factors Associated with Frailty in Old Adults: A Review of Nutritional Interventions to Prevent Frailty Development.
Hernández Morante JJ, et al. Nutrients 2019 - Review. PMID 30621313 Free PMC article.
The few studies performed to date seem to indicate that there is a protective role of protein supplementation against frailty syndrome. In this regard, it is tempting to suggest daily 30 g protein supplements to prevent frailty. However, it is well established that excess protein can also be harmful; therefore, specific individual characteristics should be considered before prescribing these supplements. ...
The few studies performed to date seem to indicate that there is a protective role of protein supplementation against frailty …
The Role of the Anabolic Properties of Plant- versus Animal-Based Protein Sources in Supporting Muscle Mass Maintenance: A Critical Review.
Berrazaga I, et al. Nutrients 2019 - Review. PMID 31394788 Free PMC article.
We evaluated and discussed four nutritional strategies for improving the amino acid composition of plant-based proteins: fortifying plant-based proteins with specific essential amino acids, selective breeding, blending several plant protein sources, and blending plant with animal-based protein sources. These nutritional approaches need to be profoundly examined in older individuals in order to optimize protein intake for this population who require a high-quality food protein intake to mitigate age-related muscle loss....
We evaluated and discussed four nutritional strategies for improving the amino acid composition of plant-based proteins: fortifying p …
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