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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 18
1946 87
1947 102
1948 112
1949 122
1950 84
1951 299
1952 593
1953 610
1954 620
1955 726
1956 711
1957 696
1958 706
1959 894
1960 987
1961 1011
1962 1129
1963 2184
1964 2584
1965 1894
1966 1870
1967 1741
1968 1790
1969 1755
1970 1545
1971 1611
1972 1616
1973 1573
1974 1664
1975 1969
1976 2095
1977 1932
1978 2326
1979 2473
1980 2624
1981 2606
1982 2678
1983 2742
1984 2836
1985 2627
1986 3092
1987 3127
1988 3177
1989 3192
1990 3108
1991 3096
1992 3091
1993 2723
1994 2781
1995 2696
1996 2697
1997 2662
1998 2767
1999 2921
2000 2876
2001 2876
2002 2958
2003 3348
2004 3424
2005 3967
2006 4152
2007 4400
2008 4587
2009 4926
2010 5461
2011 5836
2012 6322
2013 6266
2014 6179
2015 6055
2016 6000
2017 5402
2018 5394
2019 2414
2020 43
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181,840 results
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Page 1
Animal models of multiple sclerosis: From rodents to zebrafish.
Burrows DJ, et al. Mult Scler 2019 - Review. PMID 30319015
Multiple sclerosis (MS) is a chronic, immune-mediated demyelinating disease of the central nervous system. Animal models of MS have been critical for elucidating MS pathological mechanisms and how they may be targeted for therapeutic intervention. Here we review the most commonly used animal models of MS. Although these animal models cannot fully replicate the MS disease course, a number of models have been developed to recapitulate certain stages. ...
Multiple sclerosis (MS) is a chronic, immune-mediated demyelinating disease of the central nervous system. Animal models
Animal models of diabetes mellitus.
Rees DA and Alcolado JC. Diabet Med 2005 - Review. PMID 15787657
Selective inbreeding has produced several strains of animal that are considered reasonable models of Type 1 diabetes, Type 2 diabetes and related phenotypes such as obesity and insulin resistance. ...In recent years, molecular biological techniques have produced a large number of new animal models for the study of diabetes, including knock-in, generalized knock-out and tissue-specific knockout mice....
Selective inbreeding has produced several strains of animal that are considered reasonable models of Type 1 diabetes, Type 2 d …
Animal models of human pathology 2013.
Fedele M, et al. Biomed Res Int 2014. PMID 24701586 Free PMC article.
Animal models of disease.
McCabe PM, et al. Physiol Behav 2000 - Review. PMID 10713290
INTRODUCTION: Immune Relevant Animal Models: Opportunities and Challenges.
Jungersen G and Piedrahita J. ILAR J 2018. PMID 31553432
Valid interpretation of preclinical animal models in immunology-related clinical challenges is important to solve outstanding clinical needs. Given the overall complexity of the immune system and both species- and tissue-specific immune peculiarities, the selection and design of appropriate immune-relevant animal models is, however, not following a straightforward path. ...
Valid interpretation of preclinical animal models in immunology-related clinical challenges is important to solve outstanding …
Animal models of sepsis.
Zanotti-Cavazzoni SL and Goldfarb RD. Crit Care Clin 2009 - Review. PMID 19892248
In this review, we start with a general discussion of relevant factors that can determine the validity of a sepsis animal model. We briefly review some of the currently used animal models of sepsis (small animal models and large animal models). We discuss the clinical relevance of animal models in sepsis research today and address potential reasons for the apparent underperformance of animal models in predicting therapeutic success of novel drugs in clinical trials....
In this review, we start with a general discussion of relevant factors that can determine the validity of a sepsis animal model. We b …
Animal Models of Human Pathology 2016.
Fedele M, et al. Biomed Res Int 2016. PMID 28101508 Free PMC article.
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