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Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo.
Biswas S, Dodwadkar NS, Deshpande PP, Torchilin VP. Biswas S, et al. Among authors: dodwadkar ns. J Control Release. 2012 May 10;159(3):393-402. doi: 10.1016/j.jconrel.2012.01.009. Epub 2012 Jan 20. J Control Release. 2012. PMID: 22286008 Free PMC article.