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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 2
2004 1
2005 1
2007 2
2008 5
2009 4
2010 1
2011 5
2012 4
2013 3
2014 4
2015 6
2016 7
2017 5
2018 5
2019 4
2020 5
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57 results
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Page 1
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism.
Turner N, Lim XY, Toop HD, Osborne B, Brandon AE, Taylor EN, Fiveash CE, Govindaraju H, Teo JD, McEwen HP, Couttas TA, Butler SM, Das A, Kowalski GM, Bruce CR, Hoehn KL, Fath T, Schmitz-Peiffer C, Cooney GJ, Montgomery MK, Morris JC, Don AS. Turner N, et al. Among authors: don as. Nat Commun. 2018 Aug 21;9(1):3165. doi: 10.1038/s41467-018-05613-7. Nat Commun. 2018. PMID: 30131496 Free PMC article.
Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy.
von Jonquieres G, Spencer ZHT, Rowlands BD, Klugmann CB, Bongers A, Harasta AE, Parley KE, Cederholm J, Teahan O, Pickford R, Delerue F, Ittner LM, Fröhlich D, McLean CA, Don AS, Schneider M, Housley GD, Rae CD, Klugmann M. von Jonquieres G, et al. Among authors: don as. Acta Neuropathol. 2018 Jan;135(1):95-113. doi: 10.1007/s00401-017-1784-9. Epub 2017 Nov 7. Acta Neuropathol. 2018. PMID: 29116375 Free PMC article.
Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease.
Lei M, Teo JD, Song H, McEwen HP, Yup Lee J, Couttas TA, Duncan T, Chesworth R, Bertz J, Przybyla M, Van Eersel J, Heng B, Guillemin GJ, Ittner LM, Fath T, Garner B, Ittner A, Karl T, Don AS. Lei M, et al. Among authors: don as. J Neurosci. 2019 Nov 27;39(48):9645-9659. doi: 10.1523/JNEUROSCI.0524-19.2019. Epub 2019 Oct 22. J Neurosci. 2019. PMID: 31641049 Free PMC article.
Targeting mTOR as a novel therapeutic strategy for traumatic CNS injuries.
Don AS, Tsang CK, Kazdoba TM, D'Arcangelo G, Young W, Zheng XF. Don AS, et al. Drug Discov Today. 2012 Aug;17(15-16):861-8. doi: 10.1016/j.drudis.2012.04.010. Epub 2012 Apr 27. Drug Discov Today. 2012. PMID: 22569182 Free PMC article. Review.
Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration.
Couttas TA, Kain N, Tran C, Chatterton Z, Kwok JB, Don AS. Couttas TA, et al. Among authors: don as. J Alzheimers Dis. 2018;63(2):503-514. doi: 10.3233/JAD-171054. J Alzheimers Dis. 2018. PMID: 29660940
Mitochondria as cancer drug targets.
Don AS, Hogg PJ. Don AS, et al. Trends Mol Med. 2004 Aug;10(8):372-8. doi: 10.1016/j.molmed.2004.06.005. Trends Mol Med. 2004. PMID: 15310457 Review.
Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice.
Tonkin RS, Bowles C, Perera CJ, Keating BA, Makker PGS, Duffy SS, Lees JG, Tran C, Don AS, Fath T, Liu L, O'Carroll SJ, Nicholson LFB, Green CR, Gorrie C, Moalem-Taylor G. Tonkin RS, et al. Among authors: don as. Exp Neurol. 2018 Feb;300:1-12. doi: 10.1016/j.expneurol.2017.10.016. Epub 2017 Oct 18. Exp Neurol. 2018. PMID: 29055716
High FA2H and UGT8 transcript levels predict hydroxylated hexosylceramide accumulation in lung adenocarcinoma.
Lemay AM, Courtemanche O, Couttas TA, Jamsari G, Gagné A, Bossé Y, Joubert P, Don AS, Marsolais D. Lemay AM, et al. Among authors: don as. J Lipid Res. 2019 Oct;60(10):1776-1786. doi: 10.1194/jlr.M093955. Epub 2019 Aug 13. J Lipid Res. 2019. PMID: 31409741
Re-configuration of sphingolipid metabolism by oncogenic transformation.
Don AS, Lim XY, Couttas TA. Don AS, et al. Biomolecules. 2014 Mar 14;4(1):315-53. doi: 10.3390/biom4010315. Biomolecules. 2014. PMID: 24970218 Free PMC article. Review.
Fluorescent Assays for Ceramide Synthase Activity.
Couttas TA, Don AS. Couttas TA, et al. Among authors: don as. Methods Mol Biol. 2016;1376:23-33. doi: 10.1007/978-1-4939-3170-5_3. Methods Mol Biol. 2016. PMID: 26552672
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