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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1963 1
1966 1
1971 3
1972 32
1973 72
1974 137
1975 150
1976 215
1977 252
1978 351
1979 392
1980 526
1981 510
1982 631
1983 574
1984 661
1985 732
1986 714
1987 777
1988 819
1989 926
1990 982
1991 932
1992 1073
1993 1055
1994 1217
1995 1239
1996 1243
1997 1244
1998 1369
1999 1390
2000 1548
2001 1568
2002 1680
2003 1786
2004 2060
2005 2337
2006 2703
2007 2922
2008 3228
2009 3700
2010 4322
2011 4962
2012 5198
2013 5480
2014 5801
2015 6010
2016 6043
2017 5905
2018 5738
2019 3267
2020 50
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86,894 results
Results by year
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Page 1
Drug Carriers: Not an Innocent Delivery Man.
Yeo Y and Kim BK. AAPS J 2015 - Review. PMID 26017163 Free PMC article.
Biomaterials used as drug carriers are often considered inactive and assumed to have no other roles than modifying pharmacokinetics and biodistribution of a drug. ...This review highlights several examples where biomaterials used as drug carriers bring biological effects, known or newly discovered, and discusses their implications in development of new drug delivery systems....
Biomaterials used as drug carriers are often considered inactive and assumed to have no other roles than modifying pharmacokin …
Nanoparticles as carriers for drug delivery in cancer.
Dadwal A, et al. Artif Cells Nanomed Biotechnol 2018 - Review. PMID 30043651
Cancer nanotherapeutics are swiftly progressing and are being applied to solve several limitations of conventional drug delivery systems such as non-specific biodistribution and targeting, lack of water solubility and poor oral bioavailability. ...By selectively using the unique pathophysiology of tumours, such as their enhanced permeability and retention effect nanotherapeutics are able to carry loaded active drug to cancer cells. ...
Cancer nanotherapeutics are swiftly progressing and are being applied to solve several limitations of conventional drug delivery syst …
Nano-sized drug carriers: Extravasation, intratumoral distribution, and their modeling.
Nichols JW, et al. J Control Release 2017 - Review. PMID 28807683
Such a long list imposes significant requirements on nano-sized carriers. Unfortunately, other capabilities are eclipsed by the distribution requirements. A drug can do no good until it reaches its target. Numerous strategies to improve drug distribution have been developed, taking account of various unique characteristics of solid tumors, including some mechanisms that are still not fully understood. ...
Such a long list imposes significant requirements on nano-sized carriers. Unfortunately, other capabilities are eclipsed by the distr …
Emerging Frontiers in Drug Delivery.
Tibbitt MW, et al. J Am Chem Soc 2016 - Review. PMID 26741786
Drug delivery can affect drug pharmacokinetics, absorption, distribution, metabolism, duration of therapeutic effect, excretion, and toxicity. ...In this Perspective, we provide an historical overview of drug delivery and controlled release followed by highlights of four emerging areas in the field of drug delivery: systemic RNA delivery, drug delivery for localized therapy, oral drug delivery systems, and biologic drug delivery systems. ...
Drug delivery can affect drug pharmacokinetics, absorption, distribution, metabolism, duration of therapeutic effect, excretio
Synthetic Lipoproteins as Carriers for Drug Delivery.
Huang G, et al. Curr Med Chem 2016 - Review. PMID 27781947
Synthetic lipoprotein is an effective carrier of targeted delivery for drugs. It has the very small size, good biocompatibility, suitable half-life, and specific lipoprotein receptorbinding capacity. ...Herein, the advantages, development, applications, and prospect of synthetic lipoproteins as drug carriers were summarized....
Synthetic lipoprotein is an effective carrier of targeted delivery for drugs. It has the very small size, good biocompatibility, suit …
Unintended effects of drug carriers: Big issues of small particles.
Parhiz H, et al. Adv Drug Deliv Rev 2018 - Review. PMID 30149885 Free PMC article.
These policing forces recognize engineered sub-micron drug delivery systems (DDS) as such a threat, and react accordingly. This leads to impediment of the therapeutic action, extensively studied and discussed in the literature. ...We argue that for nanomedicine to reach its clinical potential, the field must redouble its efforts in understanding the interaction between drug delivery systems and the host defenses, so that we can engineer safer interventions with the greatest potential for clinical success....
These policing forces recognize engineered sub-micron drug delivery systems (DDS) as such a threat, and react accordingly. This leads …
Stimuli-responsive nanocarriers for drug delivery.
Mura S, et al. Nat Mater 2013 - Review. PMID 24150417
Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive devices that deliver a drug in spatial-, temporal- and dosage-controlled fashions have become possible. ...In this Review, we discuss recent advances in the design of nanoscale stimuli-responsive systems that are able to control drug biodistribution in response to specific stimuli, either exogenous (variations in temperature, magnetic field, ultrasound intensity, light or electric pulses) or endogenous (changes in pH, enzyme concentration or redox gradients)....
Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive devices that deliver a drug in spatial …
Drug-conjugated polymers as gene carriers for synergistic therapeutic effect.
Pofali PA, et al. J Biomed Mater Res B Appl Biomater 2016 - Review. PMID 26471335
While chemical interaction of drug-polymer overcomes the aforementioned obstacle, several problems such as steric hindrance, solubility, and biodegradability hinder it to develop as gene carrier. Considering these benefits and pitfalls, the objective of this review is to discuss the possible extent of drug-conjugated polymers as safe and efficient gene delivery carriers for achieving synergistic effect to combat various genetic disorders....
While chemical interaction of drug-polymer overcomes the aforementioned obstacle, several problems such as steric hindrance, solubili …
Quantitative self-assembly prediction yields targeted nanomedicines
Shamay Y, et al. Nat Mater 2018. PMID 29403054 Free PMC article.
Development of targeted nanoparticle drug carriers often requires complex synthetic schemes involving both supramolecular self-assembly and chemical modification. ...This finding enables the computational design of nanomedicines based on quantitative models for drug payload selection....
Development of targeted nanoparticle drug carriers often requires complex synthetic schemes involving both supramolecular self …
Application of DPD in the design of polymeric nano-micelles as drug carriers.
Ramezani M and Shamsara J. J Mol Graph Model 2016 - Review. PMID 26990730
Developing new drug carrier systems are of a great importance in the treatment approach for a wide range of diseases. The simulation techniques can be valuable for decreasing the time and cost of developing novel drug carriers. ...Here, we reviewed the results of the studies employing DPD for the simulation of drug loading and release in different polymeric micelles carriers. ...
Developing new drug carrier systems are of a great importance in the treatment approach for a wide range of diseases. The simu …
86,894 results
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