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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1951 1
1953 2
1954 1
1955 4
1956 5
1957 1
1959 4
1960 9
1961 10
1962 26
1963 5
1964 7
1965 7
1966 2
1967 6
1968 6
1969 2
1970 17
1971 46
1972 130
1973 623
1974 1778
1975 2103
1976 2428
1977 2422
1978 2359
1979 1893
1980 1050
1981 1044
1982 1145
1983 1374
1984 1564
1985 1661
1986 1773
1987 1708
1988 1952
1989 2152
1990 2164
1991 1727
1992 1303
1993 634
1994 438
1995 378
1996 373
1997 406
1998 383
1999 322
2000 293
2001 266
2002 388
2003 361
2004 340
2005 371
2006 325
2007 326
2008 291
2009 236
2010 190
2011 255
2012 220
2013 176
2014 181
2015 144
2016 110
2017 86
2018 98
2019 46
2020 1
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41,842 results
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Page 1
Economic evaluation in collaborative hospital drug evaluation reports.
Ortega A, et al. Farm Hosp 2015. PMID 26546941 Free article.
OBJECTIVE: economic evaluation is a fundamental criterion when deciding a drug's place in therapy. The MADRE method (Method for Assistance in making Decisions and Writing Drug Evaluation Reports) is widely used for drug evaluation. ...METHOD: economic evaluation sections in collaboratively conducted drug evaluation reports (as the scientific society, SEFH) with the MADRE method were reviewed retrospectively. ...
OBJECTIVE: economic evaluation is a fundamental criterion when deciding a drug's place in therapy. The MADRE method (Method fo …
A Refined Developability Classification System
Rosenberger J, et al. J Pharm Sci 2018. PMID 29665381
The DCS was designed to close the gap between the biopharmaceutics classification system, which is aimed at guiding regulatory decisions about well-characterized drugs, and the need for early evaluation of drug candidates with respect to their suitability for oral delivery. ...In addition, the rDCS offers facile visualization of the results, enabling pragmatic comparison of drug candidates and formulation approaches....
The DCS was designed to close the gap between the biopharmaceutics classification system, which is aimed at guiding regulatory decisions abo …
Optimal two-stage designs for phase II clinical trials
Simon R. Control Clin Trials 1989. PMID 2702835
The primary objective of a phase II clinical trial of a new drug or regimen is to determine whether it has sufficient biological activity against the disease under study to warrant more extensive development. ...
The primary objective of a phase II clinical trial of a new drug or regimen is to determine whether it has sufficient biological acti …
Current opinion: safety evaluation of drug metabolites in development of pharmaceuticals.
Naito S, et al. J Toxicol Sci 2007 - Review. PMID 17965548 Free article.
Safety assessment of drug metabolites in the development of pharmaceuticals was discussed in January 2007 at the kick-off meeting of a "Drug Evaluation Forum", with reference to the views of clinicians and other academic representatives. Safety evaluation of metabolites cannot readily be based on a single theoretical framework, and basically a case-by-case approach is called for. ...
Safety assessment of drug metabolites in the development of pharmaceuticals was discussed in January 2007 at the kick-off meeting of …
Quinupristin/dalfopristin
Blondeau JM and Sanche SE. Expert Opin Pharmacother 2002 - Review. PMID 12186626
Plasmonic Au nanostar Raman probes coupling with highly ordered TiO(2)/Au nanotube arrays as the reliable SERS sensing platform for chronic myeloid leukemia drug evaluation.
Wen S, et al. Biosens Bioelectron 2018. PMID 29909197
The accurate therapeutic evaluation for chronic myeloid leukemia (CML) drug is of great importance to minimize side effects and enhance efficacy. ...The developed method possesses fascinating advantages of cost-effectiveness, excellent reproducibility and high sensitivity, which endows it with promising potential in apoptosis monitoring and anticancer drug development....
The accurate therapeutic evaluation for chronic myeloid leukemia (CML) drug is of great importance to minimize side effects an …
41,842 results
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