Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 3
1947 5
1948 4
1949 3
1950 4
1951 6
1952 5
1953 3
1954 4
1956 1
1957 2
1958 1
1959 3
1961 2
1962 3
1963 3
1964 1
1967 1
1970 2
1974 5
1975 60
1976 94
1977 116
1978 110
1979 129
1980 91
1981 118
1982 110
1983 134
1984 157
1985 126
1986 147
1987 141
1988 143
1989 174
1990 182
1991 169
1992 239
1993 203
1994 226
1995 255
1996 216
1997 217
1998 224
1999 198
2000 223
2001 244
2002 277
2003 300
2004 260
2005 309
2006 299
2007 269
2008 218
2009 215
2010 234
2011 223
2012 292
2013 349
2014 364
2015 393
2016 410
2017 379
2018 308
2019 154
2020 3
Text availability
Article attribute
Article type
Publication date

Search Results

9,086 results
Results by year
Filters applied: . Clear all
Page 1
[Implants for drug substance delivery].
Blanchemain N, et al. Med Sci (Paris) 2017 - Review. PMID 28120753 French. Free article.
Implants for controlled drug delivery can be very helpful to improve the therapeutic efficacy of a medical treatment, and at the same time reduce the risk of toxic side effects. ...But this is only a restricted selection, and numerous other approaches and applications based on implants releasing a drug (or a combination of drugs) exist. ...
Implants for controlled drug delivery can be very helpful to improve the therapeutic efficacy of a medical treatment, and at t
Drug loading of polymer implants by supercritical CO2 assisted impregnation: A review.
Champeau M, et al. J Control Release 2015 - Review. PMID 25953410
Drug loaded implants also called drug-eluting implants have proven their benefits over simple implants. Among the developed manufacturing processes, the supercritical CO2 (scCO2) assisted impregnation has attracted growing attention to load Active Pharmaceutical Ingredients into polymer implants since it enables to recover a final implant free of any solvent residue and to operate under mild temperature which is suitable for processing with thermosensitive drugs. This paper is a review of the state-of-the-art and the application of the scCO2 assisted impregnation process to prepare drug-eluting implants. ...
Drug loaded implants also called drug-eluting implants have proven their benefits over simple implants. A
Mediating bone regeneration by means of drug eluting implants: From passive to smart strategies.
Bagherifard S. Mater Sci Eng C Mater Biol Appl 2017 - Review. PMID 27987680
Herein, recent advancements in fabrication of synthetic load bearing implants equipped with various drug delivery systems are reviewed. ...The future trend of implants with bone drug delivery mechanisms and the most common challenges hindering commercialization and the bench to bedside progress of the developed technologies are covered....
Herein, recent advancements in fabrication of synthetic load bearing implants equipped with various drug delivery systems are …
Recent Advances in Polymeric Implants.
Ahmed KK, et al. AAPS PharmSciTech 2019 - Review. PMID 31482251
Implantable drug delivery systems, such as drug pumps and polymeric drug depots, have emerged as means of providing predetermined drug release profiles at the desired site of action. While initial implants aimed at providing an enduring drug supply, developments in polymer chemistry and pharmaceutical technology and the growing need for refined drug delivery patterns have prompted the design of sophisticated drug delivery implants such as on-demand drug-eluting implants and personalized 3D printed implants. ...
Implantable drug delivery systems, such as drug pumps and polymeric drug depots, have emerged as means of provid
Assessing the potential of mathematical modelling in designing drug-releasing orthopaedic implants.
King D and McGinty S. J Control Release 2016 - Review. PMID 27521893 Free article.
Orthopaedic implants have been the subject of intense research in recent years, with academics, clinicians and industrialists seeking to broaden our understanding of their function and potential consequences within the human body. ...For instance, a mathematical model can help identify key drug release mechanisms and uncover the rate limiting processes; allow for the estimation of values of the parameters controlling the system; quantify the effect of the interaction with the biological environment; and aid with the design of optimisation strategies for controlled drug release. ...
Orthopaedic implants have been the subject of intense research in recent years, with academics, clinicians and industrialists seeking …
Hormonal Contraceptives and Acne: A Retrospective Analysis of 2147 Patients
Lortscher D, et al. J Drugs Dermatol 2016. PMID 27272072
<BR /> RESULTS: Depot injections, subdermal implants, and hormonal intrauterine devices worsened acne on average, and were inferior to the vaginal ring and combined oral contraceptives (COCs; <em>P</em> &le; .001 for all pairwise comparisons), which improved acne on average. ...

RESULTS: Depot injections, subdermal implants, and hormonal intrauterine devices worsened acne on average, and were infe …
Etoposide-Loaded Poly(Lactic-co-Glycolic Acid) Intravitreal Implants: In Vitro and In Vivo Evaluation.
Solano AGR, et al. AAPS PharmSciTech 2018. PMID 29516291
In vitro drug release was investigated and the implant degradation was monitored by the percent of mass loss. Implants were inserted into the vitreous cavity of rabbits' eye and the in vivo etoposide release profile was determined. ...In vitro, implants promoted sustained release of the drug and approximately 57% of the etoposide was released in 50 days. In vivo, devices released approximately 63% of the loaded drug in 42 days. ...
In vitro drug release was investigated and the implant degradation was monitored by the percent of mass loss. Implants
Microparticle entrapment for drug release from porous-surfaced bone implants.
Wang D, et al. J Microencapsul 2015. PMID 26057256
Metallic bone implants face interfacial concerns, such as infection and insufficient bone formation. Combination of drug-loaded microparticles with the implant surface is a promising approach to reducing the concerns. ...These suggest that the microparticle entrapment-based method is a promising method for reducing some of the bone-implant interfacial concerns....
Metallic bone implants face interfacial concerns, such as infection and insufficient bone formation. Combination of drug-loade …
Characterization of silicone pressure-sensitive adhesive episcleral implant for drug delivery.
Wen H and Li SK. Drug Dev Ind Pharm 2016. PMID 25923417
The silicone PSA episcleral implants in the present study had an average diameter of 3.5 mm and a thickness of 0.8 mm. Drug release from the silicone PSA implants was influenced by drug solubility, implant polymer content, and implant coating. ...Increasing polymer content in the implants led to a significant decrease in the drug release rate. Coated implants reduced the initial burst effect and provided lower release rates than the uncoated implants. ...
The silicone PSA episcleral implants in the present study had an average diameter of 3.5 mm and a thickness of 0.8 mm. Drug re …
9,086 results
Jump to page
Feedback