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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 5
1946 6
1947 15
1948 30
1949 15
1950 9
1951 23
1952 17
1953 28
1954 15
1955 13
1956 4
1957 10
1958 10
1959 16
1960 20
1961 11
1962 19
1963 43
1964 84
1965 106
1966 138
1967 227
1968 259
1969 286
1970 336
1971 317
1972 303
1973 357
1974 400
1975 268
1976 243
1977 265
1978 223
1979 288
1980 227
1981 228
1982 338
1983 270
1984 300
1985 366
1986 352
1987 319
1988 425
1989 434
1990 420
1991 514
1992 579
1993 517
1994 646
1995 663
1996 650
1997 729
1998 770
1999 833
2000 1013
2001 1573
2002 2586
2003 3086
2004 3279
2005 3888
2006 4260
2007 4567
2008 4499
2009 3885
2010 4023
2011 4532
2012 4896
2013 4854
2014 5191
2015 5129
2016 5338
2017 5518
2018 5720
2019 2872
2020 37
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86,742 results
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Page 1
Resistance of Bacteria to Biocides.
Maillard JY. Microbiol Spectr 2018 - Review. PMID 29676244
One concern is that such intense usage of biocides could lead to increased bacterial resistance to a product and cross-resistance to unrelated antimicrobials including chemotherapeutic antibiotics. ...The sections provide evidence of the occurrence of bacterial resistance and its mechanisms of action and debate how to measure bacterial resistance to biocides. ...
One concern is that such intense usage of biocides could lead to increased bacterial resistance to a product and cross-resi
Antibiotic Resistance.
Yelin I and Kishony R. Cell 2018. PMID 29474914 Free article.
Bacterial mechanisms of drug resistance operate at sequential lines of defense tackling drug at entry, accumulation, target binding, or downstream toxicity. ...A many-to-many relationship prevails between resistance mechanisms and the spectrum of genetic changes encoding them....
Bacterial mechanisms of drug resistance operate at sequential lines of defense tackling drug at entry, accumulat
Antimicrobial Resistance in Nontyphoidal Salmonella.
McDermott PF, et al. Microbiol Spectr 2018 - Review. PMID 30027887
Non-typhoidal Salmonella is the most common foodborne bacterial pathogen in most countries. It is widely present in food animal species, and therefore blocking its transmission through the food supply is a prominent focus of food safety activities worldwide. Antibiotic resistance in non-typhoidal Salmonella arises in large part because of antibiotic use in animal husbandry. Tracking resistance in Salmonella is required to design targeted interventions to contain or diminish resistance and refine use practices in production. ...
Non-typhoidal Salmonella is the most common foodborne bacterial pathogen in most countries. It is widely present in food animal speci …
Antibiotic resistance in Enterobacteriaceae: mechanisms and clinical implications.
Iredell J, et al. BMJ 2016 - Review. PMID 26858245
Resistance of the Enterobacteriaceae to antibiotics, especially of the β lactam type, is increasingly dominated by the mobilization of continuously expressed single genes that encode efficient drug modifying enzymes. Strong and ubiquitous selection pressure has seemingly been accompanied by a shift from "natural" resistance, such as inducible chromosomal enzymes, membrane impermeability, and drug efflux, to the modern paradigm of mobile gene pools that largely determine the epidemiology of modern antibiotic resistance. ...
Resistance of the Enterobacteriaceae to antibiotics, especially of the β lactam type, is increasingly dominated by the mobilization o
Antimicrobial Resistance in Campylobacter spp.
Shen Z, et al. Microbiol Spectr 2018 - Review. PMID 29623873
To cope with the selection pressure from antimicrobial use in both veterinary and human medicine, Campylobacter has developed multiple mechanisms for antibiotic resistance, including modification or mutation of antimicrobial targets, modification or inactivation of antibiotics, and reduced drug accumulation by drug efflux pumps. Some of these mechanisms confer resistance to a specific class of antimicrobials, while others give rise to multidrug resistance. ...
To cope with the selection pressure from antimicrobial use in both veterinary and human medicine, Campylobacter has developed multiple mecha …
MycoResistance: a curated resource of drug resistance molecules in Mycobacteria.
Dai E, et al. Database (Oxford) 2019. PMID 31290951 Free PMC article.
The emergence and spread of drug-resistant Mycobacterium tuberculosis is of global concern. To improve the understanding of drug resistance in Mycobacteria, numerous studies have been performed to discover diagnostic markers and genetic determinants associated with resistance to anti-tuberculosis drug. ...In addition, multidrug resistance and extensively drug resistance molecules were also extracted to interpret the molecular mechanisms that are responsible for cross resistance among anti-tuberculosis drugs. ...
The emergence and spread of drug-resistant Mycobacterium tuberculosis is of global concern. To improve the understanding of drug
Role of pharmacists in antimicrobial stewardship programmes
Garau J and Bassetti M. Int J Clin Pharm 2018 - Review. PMID 30242589
Antimicrobial resistance is a growing public health problem of global concern and, unless action is taken, the burden of death could reach 10 million per year by 2050. Resistance has been associated with increasing mortality, treatment failure and healthcare costs. In order to help combat this, antimicrobial stewardship programmes, have been implemented in many countries. ...
Antimicrobial resistance is a growing public health problem of global concern and, unless action is taken, the burden of death could …
Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions
Schwechheimer C and Kuehn MJ. Nat Rev Microbiol 2015 - Review. PMID 26373371 Free PMC article.
The production of OMVs allows bacteria to interact with their environment, and OMVs have been found to mediate diverse functions, including promoting pathogenesis, enabling bacterial survival during stress conditions and regulating microbial interactions within bacterial communities. ...
The production of OMVs allows bacteria to interact with their environment, and OMVs have been found to mediate diverse functions, including …
Tackling antibiotic resistance: the environmental framework.
Berendonk TU, et al. Nat Rev Microbiol 2015 - Review. PMID 25817583
Antibiotic resistance is a threat to human and animal health worldwide, and key measures are required to reduce the risks posed by antibiotic resistance genes that occur in the environment. ...In this Opinion article, we discuss the main knowledge gaps, the future research needs and the policy and management options that should be prioritized to tackle antibiotic resistance in the environment....
Antibiotic resistance is a threat to human and animal health worldwide, and key measures are required to reduce the risks posed by an …
Molecular Methods for Detection of Antimicrobial Resistance.
Anjum MF, et al. Microbiol Spectr 2017 - Review. PMID 29219107
The increase in bacteria harboring antimicrobial resistance (AMR) is a global problem because there is a paucity of antibiotics available to treat multidrug-resistant bacterial infections in humans and animals. ...
The increase in bacteria harboring antimicrobial resistance (AMR) is a global problem because there is a paucity of antibiotics avail …
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