Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1994 1
1996 1
1998 1
1999 1
2000 6
2001 86
2002 207
2003 244
2004 273
2005 352
2006 464
2007 555
2008 568
2009 588
2010 606
2011 695
2012 804
2013 786
2014 867
2015 934
2016 958
2017 1100
2018 1114
2019 537
2020 2
Text availability
Article attribute
Article type
Publication date

Search Results

10,403 results
Results by year
Filters applied: . Clear all
Page 1
Mechanisms of Antibiotic Resistance.
Munita JM and Arias CA. Microbiol Spectr 2016 - Review. PMID 27227291 Free PMC article.
Emergence of resistance among the most important bacterial pathogens is recognized as a major public health threat affecting humans worldwide. ...In this chapter, we will describe in detail the major mechanisms of antibiotic resistance encountered in clinical practice, providing specific examples in relevant bacterial pathogens....
Emergence of resistance among the most important bacterial pathogens is recognized as a major public health threat affecting h …
Genetic Mechanisms of Antibiotic Resistance and the Role of Antibiotic Adjuvants.
Pontes DS, et al. Curr Top Med Chem 2018 - Review. PMID 29412107
Both the environment, and genetic settings contribute to alterations in phenotypic resistance (natural bacterial evolution), and make it difficult to control the emergence and impacts of antibiotic resistance. ...In this review, we present and discuss both general information and examples of common genetic and molecular mechanisms related to antibiotic resistance, as well as how the expression and interactions of ARGs are important to drug resistance. ...
Both the environment, and genetic settings contribute to alterations in phenotypic resistance (natural bacterial evolution), a …
Metal Resistance and Its Association With Antibiotic Resistance.
Pal C, et al. Adv Microb Physiol 2017 - Review. PMID 28528649
This may occur when resistance genes to both antibiotics and metals/biocides are co-located together in the same cell (co-resistance), or a single resistance mechanism (e.g. an efflux pump) confers resistance to both antibiotics and biocides/metals (cross-resistance), leading to co-selection of bacterial strains, or mobile genetic elements that they carry. Here, we review antimicrobial metal resistance in the context of the antibiotic resistance problem, discuss co-selection, and highlight critical knowledge gaps in our understanding....
This may occur when resistance genes to both antibiotics and metals/biocides are co-located together in the same cell (co-resistan
Antibiotics-Peptide Conjugates Against Multidrug-resistant Bacterial Pathogens.
David AA, et al. Curr Top Med Chem 2018 - Review. PMID 30499392
The menace of multi-drug resistance by bacterial pathogens that are responsible for infectious diseases in humans and animals cannot be over-emphasized. ...In this review, we overview APCs which are used, as a strategy to combat the menace of multi-drug resistance of bacterial pathogens. ...
The menace of multi-drug resistance by bacterial pathogens that are responsible for infectious diseases in humans and a …
Antibiotic tolerance facilitates the evolution of resistance.
Levin-Reisman I, et al. Science 2017. PMID 28183996
We found that in all cases, tolerance preceded resistance. A mathematical population-genetics model showed how tolerance boosts the chances for resistance mutations to spread in the population. Thus, tolerance mutations pave the way for the rapid subsequent evolution of resistance. Preventing the evolution of tolerance may offer a new strategy for delaying the emergence of resistance....
We found that in all cases, tolerance preceded resistance. A mathematical population-genetics model showed how tolerance boosts the c …
Bacterial quorum sensing inhibitors: attractive alternatives for control of infectious pathogens showing multiple drug resistance.
Bhardwaj AK, et al. Recent Pat Antiinfect Drug Discov 2013 - Review. PMID 23394143
Quorum sensing (QS) is a bacterial communication process that depends on the bacterial population density. It involves small diffusible signaling molecules which activate the expression of myriad genes that control diverse array of functions like bioluminescence, virulence, biofilm formation, sporulation, to name a few. ...While antibiotics kill or slow down the growth of bacteria, quorum sensing inhibitors (QSIs) or quorum quenchers (QQs) attenuate bacterial virulence. ...
Quorum sensing (QS) is a bacterial communication process that depends on the bacterial population density. It involves small d …
Vancomycin-Resistant Enterococci: A Review of Antimicrobial Resistance Mechanisms and Perspectives of Human and Animal Health.
Ahmed MO and Baptiste KE. Microb Drug Resist 2018 - Review. PMID 29058560
The VRE gene operons show distinct genetic variability and apparently continued evolution leading to a variety of antimicrobial resistance phenotypes and various environmental and livestock reservoirs for the most common van genes. ...Enterococci resistance to glycopeptides and multidrug resistance warrants attention and continuous monitoring....
The VRE gene operons show distinct genetic variability and apparently continued evolution leading to a variety of antimicrobial resistanc
Antibiotic Adjuvants: Rescuing Antibiotics from Resistance.
Wright GD. Trends Microbiol 2016 - Review. PMID 27430191
Rooted in the mechanism of action of antibiotics and subject to bacterial evolution, antibiotic resistance is difficult and perhaps impossible to overcome. Nevertheless, strategies can be used to minimize the emergence and impact of resistance. Antibiotic adjuvants offer one such approach. ...
Rooted in the mechanism of action of antibiotics and subject to bacterial evolution, antibiotic resistance is difficult and pe …
Targeting Antibiotic Resistance.
Chellat MF, et al. Angew Chem Int Ed Engl 2016 - Review. PMID 27000559 Free PMC article.
The past decades have seen a dramatic worldwide increase in human-pathogenic bacteria that are resistant to one or multiple antibiotics. ...A recent world health day by the World Health Organization titled "Combat drug resistance: no action today means no cure tomorrow" triggered an increase in research activity, and several promising strategies have been developed to restore treatment options against infections by resistant bacterial pathogens....
The past decades have seen a dramatic worldwide increase in human-pathogenic bacteria that are resistant to one or multiple antibioti …
10,403 results
Jump to page
Feedback