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Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody.

Geiger M, Stubenrauch KG, Sam J, Richter WF, Jordan G, Eckmann J, Hage C, Nicolini V, Freimoser-Grundschober A, Ritter M, Lauer ME, Stahlberg H, Ringler P, Patel J, Sullivan E, Grau-Richards S, Endres S, Kobold S, Umaña P, Brünker P, Klein C. Geiger M, et al. Among authors: eckmann j. Nat Commun. 2020 Jun 24;11(1):3196. doi: 10.1038/s41467-020-16838-w. Nat Commun. 2020. PMID: 32581215 Free PMC article.

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Olesoxime improves cerebral mitochondrial dysfunction and enhances Aβ levels in preclinical models of Alzheimer's disease.

Eckert GP, Eckert SH, Eckmann J, Hagl S, Muller WE, Friedland K. Eckert GP, et al. Among authors: eckmann j. Exp Neurol. 2020 Jul;329:113286. doi: 10.1016/j.expneurol.2020.113286. Epub 2020 Mar 18. Exp Neurol. 2020. PMID: 32199815 Review.

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Mitochondrial dysfunction--a pharmacological target in Alzheimer's disease.

Eckert GP, Renner K, Eckert SH, Eckmann J, Hagl S, Abdel-Kader RM, Kurz C, Leuner K, Muller WE. Eckert GP, et al. Among authors: eckmann j. Mol Neurobiol. 2012 Aug;46(1):136-50. doi: 10.1007/s12035-012-8271-z. Epub 2012 May 3. Mol Neurobiol. 2012. PMID: 22552779 Review.

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The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models.

Maser IP, Hoves S, Bayer C, Heidkamp G, Nimmerjahn F, Eckmann J, Ries CH. Maser IP, et al. Among authors: eckmann j. Front Immunol. 2020 Sep 8;11:2082. doi: 10.3389/fimmu.2020.02082. eCollection 2020. Front Immunol. 2020. PMID: 33013879 Free PMC article.

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Mitochondria: mitochondrial membranes in brain ageing and neurodegeneration.

Eckmann J, Eckert SH, Leuner K, Muller WE, Eckert GP. Eckmann J, et al. Int J Biochem Cell Biol. 2013 Jan;45(1):76-80. doi: 10.1016/j.biocel.2012.06.009. Epub 2012 Jun 26. Int J Biochem Cell Biol. 2013. PMID: 22743330

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Dimebon ameliorates amyloid-β induced impairments of mitochondrial form and function.

Eckert SH, Eckmann J, Renner K, Eckert GP, Leuner K, Muller WE. Eckert SH, et al. Among authors: eckmann j. J Alzheimers Dis. 2012;31(1):21-32. doi: 10.3233/JAD-2012-120310. J Alzheimers Dis. 2012. PMID: 22475801

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CD25-T_reg-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity.

Solomon I, Amann M, Goubier A, Vargas FA, Zervas D, Qing C, Henry JY, Ghorani E, Akarca AU, Marafioti T, Śledzińska A, Sunderland MW, Demane DF, Clancy JR, Georgiou A, Salimu J, Merchiers P, Brown MA, Flury R, Eckmann J, Murgia C, Sam J, Jacobsen B, Marrer-Berger E, Boetsch C, Belli S, Leibrock L, Benz J, Koll H, Sutmuller R, Peggs KS, Quezada SA. Solomon I, et al. Among authors: eckmann j. Nat Cancer. 2020 Dec;1(12):1153-1166. doi: 10.1038/s43018-020-00133-0. Epub 2020 Nov 9. Nat Cancer. 2020. PMID: 33644766 Free PMC article.

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Liposome-incorporated DHA increases neuronal survival by enhancing non-amyloidogenic APP processing.

Eckert GP, Chang S, Eckmann J, Copanaki E, Hagl S, Hener U, Müller WE, Kögel D. Eckert GP, et al. Among authors: eckmann j. Biochim Biophys Acta. 2011 Jan;1808(1):236-43. doi: 10.1016/j.bbamem.2010.10.014. Epub 2010 Oct 29. Biochim Biophys Acta. 2011. PMID: 21036142 Free article.

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Mitochondrial membrane fluidity is consistently increased in different models of Huntington disease: restorative effects of olesoxime.

Eckmann J, Clemens LE, Eckert SH, Hagl S, Yu-Taeger L, Bordet T, Pruss RM, Muller WE, Leuner K, Nguyen HP, Eckert GP. Eckmann J, et al. Mol Neurobiol. 2014 Aug;50(1):107-18. doi: 10.1007/s12035-014-8663-3. Epub 2014 Mar 18. Mol Neurobiol. 2014. PMID: 24633813

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Homeland security and HIM.

Arellano AJ, Baxter C, Beezley DC, Boester CM, Coleman J, Eckmann J, Frazeur M, Gorton ER, Houston MM, Johnson W, Parks LI, Quinsey CA, Sender JP, Smith S, Spott MA, Stevens C, Taguchi S. Arellano AJ, et al. Among authors: eckmann j. J AHIMA. 2004 Jun;75(6):56A-56D. J AHIMA. 2004. PMID: 15216711 No abstract available.

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