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1999 2
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170 results

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Page 1
A gut Eggerthella lenta-derived metabolite impairs neutrophil function to aggravate bacterial lung infection.
Wang LL, Shen X, Xie Y, Ge A, Lu H, Gu S, Kong L, Narayana JK, Mattner J, Chotirmall SH, Xu JF. Wang LL, et al. Sci Transl Med. 2025 Feb 26;17(787):eadq4409. doi: 10.1126/scitranslmed.adq4409. Epub 2025 Feb 26. Sci Transl Med. 2025. PMID: 40009694
However, the responsible microbes and mechanisms in the "gut-lung" axis in bronchiectasis remain unknown. Here, we report that Eggerthella lenta was enriched in the gut, and taurine ursodeoxycholic acid (TUDCA) was enriched in both the guts and sera of patients with …
However, the responsible microbes and mechanisms in the "gut-lung" axis in bronchiectasis remain unknown. Here, we report that Eggerthell
Eggerthella lenta augments preclinical autoantibody production and metabolic shift mimicking senescence in arthritis.
Balakrishnan B, Luckey D, Wright K, Davis JM, Chen J, Taneja V. Balakrishnan B, et al. Sci Adv. 2023 Sep;9(35):eadg1129. doi: 10.1126/sciadv.adg1129. Epub 2023 Sep 1. Sci Adv. 2023. PMID: 37656793 Free PMC article.
Although the etiology of rheumatoid arthritis (RA) is unknown, a strong genetic predisposition and the presence of preclinical antibodies before the onset of symptoms is documented. An expansion of Eggerthella lenta is associated with severe disease in RA. Here, usi …
Although the etiology of rheumatoid arthritis (RA) is unknown, a strong genetic predisposition and the presence of preclinical antibodies be …
Eggerthella lenta bacteremia successfully treated with ceftizoxime: case report and review of the literature.
Jiang S, E J, Wang D, Zou Y, Liu X, Xiao H, Wen Y, Chen Z. Jiang S, et al. Eur J Med Res. 2021 Sep 20;26(1):111. doi: 10.1186/s40001-021-00582-y. Eur J Med Res. 2021. PMID: 34544476 Free PMC article. Review.
Eggerthella lenta is a normal human microflora that is anaerobic, non-sporulating, and Gram positive. ...
Eggerthella lenta is a normal human microflora that is anaerobic, non-sporulating, and Gram positive. ...
Cigarette smoke promotes colorectal cancer through modulation of gut microbiota and related metabolites.
Bai X, Wei H, Liu W, Coker OO, Gou H, Liu C, Zhao L, Li C, Zhou Y, Wang G, Kang W, Ng EK, Yu J. Bai X, et al. Gut. 2022 Dec;71(12):2439-2450. doi: 10.1136/gutjnl-2021-325021. Epub 2022 Apr 6. Gut. 2022. PMID: 35387878 Free PMC article.
Gut microbial dysbiosis was observed in smoke-exposed mice with significant differential abundance of bacterial species including the enrichment of Eggerthella lenta and depletion of Parabacteroides distasonis and Lactobacillus spp. Metabolomic analysis showed incre …
Gut microbial dysbiosis was observed in smoke-exposed mice with significant differential abundance of bacterial species including the enrich …
Eggerthella lenta DSM 2243 Alleviates Bile Acid Stress Response in Clostridium ramosum and Anaerostipes caccae by Transformation of Bile Acids.
Pedersen KJ, Haange SB, Žížalová K, Viehof A, Clavel T, Leniček M, Engelmann B, Wick LY, Schaap FG, Jehmlich N, Rolle-Kampczyk U, von Bergen M. Pedersen KJ, et al. Microorganisms. 2022 Oct 13;10(10):2025. doi: 10.3390/microorganisms10102025. Microorganisms. 2022. PMID: 36296301 Free PMC article.
Co-culturing with Eggerthella lenta decreased both CA and DCA by the formation of oxidized and epimerized bile acids. Eggerthella lenta also produces microbial bile salt conjugates in a co-cultured species-specific manner. ...
Co-culturing with Eggerthella lenta decreased both CA and DCA by the formation of oxidized and epimerized bile acids. Egger
Human gut bacterial metabolism drives Th17 activation and colitis.
Alexander M, Ang QY, Nayak RR, Bustion AE, Sandy M, Zhang B, Upadhyay V, Pollard KS, Lynch SV, Turnbaugh PJ. Alexander M, et al. Cell Host Microbe. 2022 Jan 12;30(1):17-30.e9. doi: 10.1016/j.chom.2021.11.001. Epub 2021 Nov 24. Cell Host Microbe. 2022. PMID: 34822777 Free PMC article.
We show that human gut Actinobacterium Eggerthella lenta induces intestinal Th17 activation by lifting inhibition of the Th17 transcription factor Rorgammat through cell- and antigen-independent mechanisms. ...
We show that human gut Actinobacterium Eggerthella lenta induces intestinal Th17 activation by lifting inhibition of the Th17 …
Identification and Antibiotic Susceptibility of Eggerthella lenta in Bloodstream Infections.
Li X, Xu E, Shi C, Qiao G, Chen S, Xu Y, Liu Y, Bao X. Li X, et al. Pol J Microbiol. 2022 Jun 19;71(2):257-261. doi: 10.33073/pjm-2022-024. Pol J Microbiol. 2022. PMID: 35716165 Free PMC article.
The identification and antibiotic susceptibility of two clinical isolates of Eggerthella lenta from bloodstream infections were determined. This microorganism is rarely pathogenic, and the findings are presented here to promote the detection and awareness of this in …
The identification and antibiotic susceptibility of two clinical isolates of Eggerthella lenta from bloodstream infections wer …
Morphological and Genetic Characterization of Eggerthella lenta Bacteriophage PMBT5.
Sprotte S, Rasmussen TS, Cho GS, Brinks E, Lametsch R, Neve H, Vogensen FK, Nielsen DS, Franz CMAP. Sprotte S, et al. Viruses. 2022 Jul 22;14(8):1598. doi: 10.3390/v14081598. Viruses. 2022. PMID: 35893664 Free PMC article.
Eggerthella lenta is a common member of the human gut microbiome. We here describe the isolation and characterization of a putative virulent bacteriophage having E. lenta as host. ...
Eggerthella lenta is a common member of the human gut microbiome. We here describe the isolation and characterization of a put
Gut bacteria convert glucocorticoids into progestins in the presence of hydrogen gas.
McCurry MD, D'Agostino GD, Walsh JT, Bisanz JE, Zalosnik I, Dong X, Morris DJ, Korzenik JR, Edlow AG, Balskus EP, Turnbaugh PJ, Huh JR, Devlin AS. McCurry MD, et al. Cell. 2024 Jun 6;187(12):2952-2968.e13. doi: 10.1016/j.cell.2024.05.005. Epub 2024 May 24. Cell. 2024. PMID: 38795705
Here, we show that the human gut bacteria Gordonibacter pamelaeae and Eggerthella lenta convert abundant biliary corticoids into progestins through 21-dehydroxylation, thereby transforming a class of immuno- and metabo-regulatory steroids into a class of sex hormone …
Here, we show that the human gut bacteria Gordonibacter pamelaeae and Eggerthella lenta convert abundant biliary corticoids in …
Selective Isolation of Eggerthella lenta from Human Faeces and Characterisation of the Species Prophage Diversity.
Buttimer C, Bottacini F, Shkoporov AN, Draper LA, Ross P, Hill C. Buttimer C, et al. Microorganisms. 2022 Jan 17;10(1):195. doi: 10.3390/microorganisms10010195. Microorganisms. 2022. PMID: 35056644 Free PMC article.
Eggerthella lenta is an anaerobic, high GC, Gram-positive bacillus commonly found in the human digestive tract that belongs to the class Coriobacteriia of the phylum Actinobacteria. ...
Eggerthella lenta is an anaerobic, high GC, Gram-positive bacillus commonly found in the human digestive tract that belongs to
170 results