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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1781 37
1782 18
1783 22
1784 27
1785 43
1786 60
1787 43
1788 33
1789 32
1790 44
1791 19
1792 33
1793 17
1794 18
1795 13
1796 14
1797 59
1798 15
1799 291
1800 377
1801 360
1802 285
1803 269
1804 289
1805 314
1806 282
1807 295
1808 289
1809 265
1810 267
1811 322
1812 238
1813 265
1814 285
1815 222
1816 315
1817 288
1818 303
1819 225
1820 213
1821 270
1822 247
1823 291
1824 269
1825 262
1826 385
1827 326
1828 409
1829 568
1830 510
1831 579
1832 284
1833 221
1834 209
1835 222
1836 220
1837 281
1838 265
1839 289
1840 395
1841 829
1842 971
1843 813
1844 609
1845 681
1846 746
1847 774
1848 799
1849 744
1850 756
1851 773
1852 765
1853 901
1854 827
1855 1090
1856 1283
1857 1275
1858 1339
1859 1319
1860 1210
1861 945
1862 904
1863 823
1864 937
1865 936
1866 1239
1867 1434
1868 1510
1869 1535
1870 1477
1871 1855
1872 1922
1873 1986
1874 2118
1875 2094
1876 1893
1877 1968
1878 2202
1879 2138
1880 2407
1881 2578
1882 2103
1883 2571
1884 2601
1885 2822
1886 2952
1887 3415
1888 3357
1889 3749
1890 3609
1891 3220
1892 3715
1893 3961
1894 3429
1895 3684
1896 3860
1897 4124
1898 4079
1899 3567
1900 3397
1901 3500
1902 3538
1903 3532
1904 3727
1905 3742
1906 3618
1907 4107
1908 4305
1909 4527
1910 4638
1911 4857
1912 4781
1913 5070
1914 5075
1915 4557
1916 4367
1917 4122
1918 4093
1919 4440
1920 5037
1921 4703
1922 4192
1923 4519
1924 4945
1925 5058
1926 5397
1927 5945
1928 5537
1929 5798
1930 5694
1931 5572
1932 5629
1933 5695
1934 5577
1935 5736
1936 5448
1937 5378
1938 5829
1939 5615
1940 5024
1941 4865
1942 4800
1943 4544
1944 4764
1945 20489
1946 53908
1947 65016
1948 70701
1949 62795
1950 85769
1951 103730
1952 108064
1953 108904
1954 105915
1955 108545
1956 107007
1957 111522
1958 109458
1959 109963
1960 112139
1961 120104
1962 125637
1963 141521
1964 162087
1965 176645
1966 179745
1967 191500
1968 207849
1969 215035
1970 218962
1971 222897
1972 227483
1973 230614
1974 234502
1975 248192
1976 250240
1977 249620
1978 257891
1979 265175
1980 266835
1981 271207
1982 282737
1983 294367
1984 302282
1985 318474
1986 330914
1987 346893
1988 363233
1989 377173
1990 382199
1991 380034
1992 381624
1993 389467
1994 401051
1995 410303
1996 420449
1997 418158
1998 435688
1999 452882
2000 489403
2001 502355
2002 519973
2003 547571
2004 590380
2005 648860
2006 693788
2007 731215
2008 777919
2009 816697
2010 878929
2011 953042
2012 1019057
2013 1070042
2014 1121934
2015 1162132
2016 1193443
2017 1213329
2018 1255633
2019 1311038
2020 1490998
2021 1624613
2022 1610626
2023 195701
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Search Results

32,966,988 results
Results by year
Filters applied: . Clear all Quoted phrases not found in phrase index: "Zinc Powder Addition", "Solution And Solubility"
Page 1
Hydroxypropyl methylcellulose: Physicochemical properties and ocular drug delivery formulations.
Tundisi LL, Mostaço GB, Carricondo PC, Petri DFS. Tundisi LL, et al. Eur J Pharm Sci. 2021 Apr 1;159:105736. doi: 10.1016/j.ejps.2021.105736. Epub 2021 Jan 28. Eur J Pharm Sci. 2021. PMID: 33516807 Review.
Hydroxypropyl methylcellulose (HPMC) is a cellulose ether widely used in drug formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior. ...The different therapeutic approaches are necessary due to the complex …
Hydroxypropyl methylcellulose (HPMC) is a cellulose ether widely used in drug formulations due to its biocompatibility, uncharged nat …
In vitro solubility assays in drug discovery.
Kerns EH, Di L, Carter GT. Kerns EH, et al. Curr Drug Metab. 2008 Nov;9(9):879-85. doi: 10.2174/138920008786485100. Curr Drug Metab. 2008. PMID: 18991584 Review.
The solubility of a compound depends on its structure and solution conditions. Structure determines the lipophilicity, hydrogen bonding, molecular volume, crystal energy and ionizability, which determine solubility. ...
The solubility of a compound depends on its structure and solution conditions. Structure determines the l …
Measuring Protein Solubility.
Asherie N. Asherie N. Methods Mol Biol. 2019;2039:51-57. doi: 10.1007/978-1-4939-9678-0_4. Methods Mol Biol. 2019. PMID: 31342418
Protein solubility determines the conditions under which the protein will remain in solution. ...This method can be used to measure the solubility of other proteins....
Protein solubility determines the conditions under which the protein will remain in solution. ...This method can be used to me …
Activity Coefficients and Solubilities of NaCl in Water-Methanol Solutions from Molecular Dynamics Simulations.
Saravi SH, Panagiotopoulos AZ. Saravi SH, et al. J Phys Chem B. 2022 Apr 21;126(15):2891-2898. doi: 10.1021/acs.jpcb.2c00813. Epub 2022 Apr 12. J Phys Chem B. 2022. PMID: 35411772
We obtain activity coefficients and solubilities of NaCl in water-methanol solutions at 298.15 K and 1 bar from molecular dynamics (MD) simulations with the Joung-Cheatham, SPC/E, and OPLS-AA force fields for NaCl, water, and methanol, respectiv …
We obtain activity coefficients and solubilities of NaCl in water-methanol solutions at 298.15 K and 1 bar from mole
Basics of Compounding with Dilutions and Concentrates.
Allen LV Jr. Allen LV Jr. Int J Pharm Compd. 2017 Jan-Feb;21(1):39-45. Int J Pharm Compd. 2017. PMID: 28346197 Review.
If the drug is not present at full strength, then adjustments may be necessary to obtain the required quantity of drug. Also, in many cases, it is necessary to use a dilution or a concentrate of a drug due to safety and quality reasons. Presented within this …
If the drug is not present at full strength, then adjustments may be necessary to obtain the required quantity of drug. Also, …
Analytical exclusion chromatography.
Winzor DJ. Winzor DJ. J Biochem Biophys Methods. 2003 Jun 30;56(1-3):15-52. doi: 10.1016/s0165-022x(03)00071-x. J Biochem Biophys Methods. 2003. PMID: 12834967 Review.
This review summarizes the development of exclusion chromatography, also termed gel filtration, molecular-sieve chromatography and gel permeation chromatography, for the quantitative characterization of solutes and solute interactions. As well as affording a …
This review summarizes the development of exclusion chromatography, also termed gel filtration, molecular-sieve chromatography and ge …
Advances in ophthalmic drug delivery.
Morrison PW, Khutoryanskiy VV. Morrison PW, et al. Ther Deliv. 2014 Dec;5(12):1297-315. doi: 10.4155/tde.14.75. Ther Deliv. 2014. PMID: 25531930 Free article. Review.
Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye. ...Futur …
Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; vi …
Molecular simulation of nonfacilitated membrane permeation.
Awoonor-Williams E, Rowley CN. Awoonor-Williams E, et al. Biochim Biophys Acta. 2016 Jul;1858(7 Pt B):1672-87. doi: 10.1016/j.bbamem.2015.12.014. Epub 2015 Dec 17. Biochim Biophys Acta. 2016. PMID: 26706099 Free article. Review.
Predicting the permeability coefficient of a solute is important in pharmaceutical chemistry and toxicology. Molecular simulation has proven to be a valuable tool for modeling permeation of solutes through a lipid bilayer. ...This article
Predicting the permeability coefficient of a solute is important in pharmaceutical chemistry and toxicology. Molecul
Chemistry of Hofmeister anions and osmolytes.
Zhang Y, Cremer PS. Zhang Y, et al. Annu Rev Phys Chem. 2010;61:63-83. doi: 10.1146/annurev.physchem.59.032607.093635. Annu Rev Phys Chem. 2010. PMID: 20055667 Review.
Such behavior depends both on the nature and concentration of the species in solution. Despite the generality of these effects, our understanding of the molecular-level details of ion and osmolyte specificity is still quite limited. Here, we review recent studies of …
Such behavior depends both on the nature and concentration of the species in solution. Despite the generality of these effects, our u …
Stability characterization, kinetics and mechanism of tacrolimus degradation in cyclodextrin solutions.
Prajapati M, Eiriksson FF, Loftsson T. Prajapati M, et al. Int J Pharm. 2020 Aug 30;586:119579. doi: 10.1016/j.ijpharm.2020.119579. Epub 2020 Jun 27. Int J Pharm. 2020. PMID: 32599134
Besides this, tacrolimus also undergoes dehydration and epimerization. Cyclodextrin (CD) complexation can increase the solubility and stability of hydrophobic drugs in aqueous solutions through the formation of drug/CD complexes. ...Mass spectrometry studies …
Besides this, tacrolimus also undergoes dehydration and epimerization. Cyclodextrin (CD) complexation can increase the solubility and …
32,966,988 results
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