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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1982 1
1984 1
1985 1
1987 1
1991 1
1992 2
1993 12
1994 15
1995 55
1996 37
1997 79
1998 87
1999 74
2000 117
2001 120
2002 154
2003 161
2004 190
2005 286
2006 287
2007 349
2008 395
2009 370
2010 329
2011 322
2012 416
2013 404
2014 393
2015 410
2016 435
2017 353
2018 349
2019 128
2020 0
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5,565 results
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Page 1
Circulating Endocannabinoids: From Whence Do They Come and Where are They Going?
Hillard CJ. Neuropsychopharmacology 2018 - Review. PMID 28653665 Free PMC article.
The roles of endocannabinoids in the regulation of energy intake and storage have been well studied and the data obtained consistently support the hypothesis that endocannabinoid signaling is associated with increased consumption and storage of energy. ...Other conditions under which circulating endocannabinoids are altered include inflammation and pain. A second important role for endocannabinoid signaling is to restore homeostasis following stress. ...
The roles of endocannabinoids in the regulation of energy intake and storage have been well studied and the data obtained consistentl …
Endocannabinoids, exercise, pain, and a path to health with aging.
Watkins BA. Mol Aspects Med 2018 - Review. PMID 30290200
The endocannabinoid system (ECS) has emerged as a focal point to ascertain the mechanisms for how exercise benefits the body and how it reduces or controls pain. ...Future research on the ECS must include mechanistic approaches to endocannabinoid signaling and explain the role of dietary PUFA in altering signaling of the receptors that affects pain. ...
The endocannabinoid system (ECS) has emerged as a focal point to ascertain the mechanisms for how exercise benefits the body and how …
Polyunsaturated fatty acids and endocannabinoids in health and disease.
Freitas HR, et al. Nutr Neurosci 2018 - Review. PMID 28686542
Polyunsaturated fatty acids (PUFAs) are lipid derivatives of omega-3 (docosahexaenoic acid, DHA, and eicosapentaenoic acid, EPA) or of omega-6 (arachidonic acid, ARA) synthesized from membrane phospholipids and used as a precursor for endocannabinoids (ECs). ...Cloning of cannabinoid receptors in the 90s and the identification of the endogenous mediators arachidonylethanolamide (anandamide, AEA) and 2-arachidonyglycerol (2-AG), led to the characterization of the endocannabinoid system (ECS), together with their metabolizing enzymes and membrane transporters. ...
Polyunsaturated fatty acids (PUFAs) are lipid derivatives of omega-3 (docosahexaenoic acid, DHA, and eicosapentaenoic acid, EPA) or of omega …
Medical Use of Cannabinoids
Fraguas-Sánchez AI and Torres-Suárez AI. Drugs 2018 - Review. PMID 30374797
Cannabinoid receptors, endocannabinoids and the enzymes responsible for their biosynthesis and degradation constitute the endocannabinoid system. ...The expression of the endocannabinoid system in the eye suggests that it could be a potential therapeutic target for eye diseases. ...
Cannabinoid receptors, endocannabinoids and the enzymes responsible for their biosynthesis and degradation constitute the endocann
Cannabis for the Treatment of Epilepsy: an Update
Gaston TE and Szaflarski JP. Curr Neurol Neurosci Rep 2018 - Review. PMID 30194563
RECENT FINDINGS: While the anticonvulsant mechanism of action of CBD has not been entirely elucidated, we discuss the most recent data available including its low affinity for the endocannabinoid receptors and possible indirect modulation of these receptors via blocking the breakdown of anandamide. ...
RECENT FINDINGS: While the anticonvulsant mechanism of action of CBD has not been entirely elucidated, we discuss the most recent data avail …
Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System.
Zou S and Kumar U. Int J Mol Sci 2018 - Review. PMID 29533978 Free PMC article.
In this review, we briefly summarized our knowledge of cannabinoids and the endocannabinoid system, focusing on the CB1R and the CNS, with emphasis on recent breakthroughs in the field. ...
In this review, we briefly summarized our knowledge of cannabinoids and the endocannabinoid system, focusing on the CB1R and the CNS, …
Marijuana Use in Pregnancy and While Breastfeeding
Metz TD and Borgelt LM. Obstet Gynecol 2018 - Review. PMID 30234728 Free PMC article.
The harms are biologically plausible given the role of the endocannabinoid system in pregnancy implantation, placentation, and fetal neurologic development. ...
The harms are biologically plausible given the role of the endocannabinoid system in pregnancy implantation, placentation, and fetal …
The cannabinoid system and pain
Woodhams SG, et al. Neuropharmacology 2017 - Review. PMID 28625720 Free PMC article.
In this article, we review the role of an important endogenous pain control system, the endocannabinoid (EC) system, in the sensory, emotional, and cognitive aspects of pain. ...Pharmacological enhancement of endocannabinoid activity (via blockade of EC metabolism or allosteric modulation of CB(1)receptors); 2. ...
In this article, we review the role of an important endogenous pain control system, the endocannabinoid (EC) system, in the sensory, …
Cannabinoids in depressive disorders
Poleszak E, et al. Life Sci 2018 - Review. PMID 30290188
It seems that the endocannabinoid system is also involved in the pathogenesis and treatment of depression, though its role in this mental disease has not been fully understood yet. Both the pro- and antidepressant activity have been reported after cannabis consumption and a number of pre-clinical studies have demonstrated that both agonist and antagonist of the endocannabinoid receptors act similarly to antidepressants. ...
It seems that the endocannabinoid system is also involved in the pathogenesis and treatment of depression, though its role in this me …
Endocannabinoids in arthritis: current views and perspective.
Barrie N, et al. Int J Rheum Dis 2017 - Review. PMID 28736968
This synopsis reviews the various components of the endocannabinoid system in health and disease and their potential as therapeutic targets....
This synopsis reviews the various components of the endocannabinoid system in health and disease and their potential as therapeutic t …
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