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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1991 5
1992 16
1993 26
1994 29
1995 29
1996 43
1997 34
1998 27
1999 36
2000 38
2001 40
2002 52
2003 58
2004 67
2005 60
2006 53
2007 61
2008 91
2009 80
2010 64
2011 72
2012 75
2013 80
2014 102
2015 88
2016 84
2017 53
2018 63
2019 24
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1,428 results
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Page 1
Premenopausal abnormal uterine bleeding and risk of endometrial cancer.
Pennant ME, et al. BJOG 2017 - Review. PMID 27766759 Free PMC article.
BACKGROUND: Endometrial biopsies are undertaken in premenopausal women with abnormal uterine bleeding but the risk of endometrial cancer or atypical hyperplasia is unclear. ...Risk of endometrial cancer was 0.33% (95% CI 0.23-0.48%, n = 29 059; 97 cases) and risk of endometrial cancer or atypical hyperplasia was 1.31% (95% CI 0.96-1.80, n = 15 772; 207 cases). ...
BACKGROUND: Endometrial biopsies are undertaken in premenopausal women with abnormal uterine bleeding but the risk of endometrial cancer or atypical hyperplasia is unclear. ...Risk of endometrial cancer was 0.33% (95% CI 0.23-0.48%, n = 29 059; 97 cases) and risk of endometri
Addressing the Role of Obesity in Endometrial Cancer Risk, Prevention, and Treatment.
Onstad MA, et al. J Clin Oncol 2016 - Review. PMID 27903150 Free PMC article.
More than half of endometrial cancers are currently attributable to obesity, which is recognized as an independent risk factor for this disease. In this review, we identify the molecular mechanisms by which obesity and adipose tissue contribute to the pathogenesis of endometrial cancer. ...
More than half of endometrial cancers are currently attributable to obesity, which is recognized as an independent risk factor for this disease. In this review, we identify the molecular mechanisms by which obesity and adipose tissue contribute to the pathogenesis of endometrial cancer …
The accuracy of endometrial sampling in women with postmenopausal bleeding: a systematic review and meta-analysis.
van Hanegem N, et al. Eur J Obstet Gynecol Reprod Biol 2016 - Review. PMID 26748390
In this systematic review, we studied the accuracy of endometrial sampling for the diagnoses of endometrial cancer, atypical hyperplasia and endometrial disease (endometrial pathology, including benign polyps). ...For each included study, we calculated the fraction of women in whom endometrial sampling failed. Furthermore, we extracted numbers of cases of endometrial cancer, atypical hyperplasia and endometrial disease that were identified or missed by endometrial sampling. ...
In this systematic review, we studied the accuracy of endometrial sampling for the diagnoses of endometrial cancer, atypical hyperplasia and endometrial disease (endometrial pathology, including benign polyps). ...For each included study, we calculated the fraction of wom …
Obesity and gynaecological and obstetric conditions: umbrella review of the literature
Kalliala I, et al. BMJ 2017 - Review. PMID 29074629 Free PMC article.
Of the 144 meta-analyses that included cohort studies, only 11 (8%) had strong evidence for eight outcomes: adiposity was associated with a higher risk of endometrial cancer, ovarian cancer, antenatal depression, total and emergency caesarean section, pre-eclampsia, fetal macrosomia, and low Apgar score. The summary effect estimates ranged from 1.21 (95% confidence interval 1.13 to 1.29) for an association between a 0.1 unit increase in waist to hip ratio and risk endometrial cancer up to 4.14 (3.61 to 4.75) for risk of pre-eclampsia for BMI >35 compared with <25. ...
Of the 144 meta-analyses that included cohort studies, only 11 (8%) had strong evidence for eight outcomes: adiposity was associated with a higher risk of endometrial cancer, ovarian cancer, antenatal depression, total and emergency caesarean section, pre-eclampsia, fetal macrosomia, and low …
Sentinel Lymph Node Biopsy in Endometrial Cancer: a New Standard of Care?
Sullivan SA and Rossi EC. Curr Treat Options Oncol 2017 - Review. PMID 28921419
Lymph node status is one of the most important factors in determining prognosis and the need for adjuvant treatment in endometrial cancer (EMCA). ...The sensitivity of sentinel lymph node identification with robotic fluorescence imaging for detecting metastatic endometrial and cervical cancer (FIRES) trial published this year is the largest prospective, multi-institution trial investigating the accuracy of the SLN biopsy for endometrial and cervical cancer. ...
Lymph node status is one of the most important factors in determining prognosis and the need for adjuvant treatment in endometrial cancer (EMCA). ...The sensitivity of sentinel lymph node identification with robotic fluorescence imaging for detecting metastatic endometrial and cervical …
Association of Endometrial Cancer Risk With Postmenopausal Bleeding in Women: A Systematic Review and Meta-analysis.
Clarke MA, et al. JAMA Intern Med 2018. PMID 30083701 Free PMC article.
OBJECTIVE: To provide a reference of the prevalence of PMB in endometrial cancers and the risk of endometrial cancer in women with PMB. ...MAIN OUTCOMES AND MEASURES: The pooled prevalence of PMB in women with endometrial cancer and the risk of endometrial cancer in women with PMB. ...
OBJECTIVE: To provide a reference of the prevalence of PMB in endometrial cancers and the risk of endometrial cancer in women with PMB. ...MAIN OUTCOMES AND MEASURES: The pooled prevalence of PMB in women with endometrial cancer and the risk of endometrial cancer in women …
Hormone replacement therapy after treatment for a gynaecological malignancy
O'Donnell RL, et al. Curr Opin Obstet Gynecol 2016 - Review. PMID 26626038
RECENT FINDINGS: Available evidence for ovarian, vulval, cervical, and endometrial cancers demonstrates no excess risk of recurrence in patients taking HRT with the exception of some subtypes of cancer (uterine sarcomas, granulosa cell, and low-grade serous ovarian cancer). ...
RECENT FINDINGS: Available evidence for ovarian, vulval, cervical, and endometrial cancers demonstrates no excess risk of recurrence in patients taking HRT with the exception of some subtypes of cancer (uterine sarcomas, granulosa cell, and low-grade serous ovarian cancer). ...
Response
Arem H, et al. J Natl Cancer Inst 2014. PMID 24389423 Free PMC article.
Prediction of concurrent endometrial carcinoma in women with endometrial hyperplasia.
Matsuo K, et al. Gynecol Oncol 2015. PMID 26238457
The aim of our study was to identify predictive clinico-pathologic factors for concurrent endometrial carcinoma among patients with endometrial hyperplasia. METHODS: A case-control study was conducted to compare endometrial hyperplasia in both preoperative endometrial biopsy and hysterectomy specimens (n=168) and endometrial carcinoma in hysterectomy specimen but endometrial hyperplasia in preoperative endometrial biopsy (n=43). ...
The aim of our study was to identify predictive clinico-pathologic factors for concurrent endometrial carcinoma among patients with endometrial hyperplasia. METHODS: A case-control study was conducted to compare endometrial hyperplasia in both preoperative endometrial bio …
Investigation of women with postmenopausal uterine bleeding: clinical practice recommendations
Munro MG and Southern California Permanente Medical Group’s Abnormal Uterine Bleeding Working Group . Perm J 2014. PMID 24377427 Free PMC article.
The guideline development group determined that, for initial management of spontaneous postmenopausal bleeding, primary assessment may be with either endometrial sampling or transvaginal ultrasonography, allowing patients with an endometrial echo complex thickness of 4 mm or less to be managed expectantly. Guidelines are also provided for patients receiving selective estrogen receptor modulators or hormone replacement therapy, and for an endometrial echo complex with findings consistent with fluid in the endometrial cavity...
The guideline development group determined that, for initial management of spontaneous postmenopausal bleeding, primary assessment may be with either endometrial sampling or transvaginal ultrasonography, allowing patients with an endometrial echo complex thickness of 4 mm or less to be …
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