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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1989 2
1990 1
1991 1
1992 2
1993 6
1994 7
1995 16
1996 24
1997 19
1998 35
1999 41
2000 39
2001 52
2002 45
2003 60
2004 45
2005 49
2006 40
2007 50
2008 59
2009 73
2010 57
2011 54
2012 58
2013 58
2014 58
2015 58
2016 64
2017 47
2018 54
2019 31
2020 1
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1,112 results
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Page 1
The Role of ClpP Protease in Bacterial Pathogenesis and Human Diseases.
Bhandari V, Wong KS, Zhou JL, Mabanglo MF, Batey RA, Houry WA. Bhandari V, et al. ACS Chem Biol. 2018 Jun 15;13(6):1413-1425. doi: 10.1021/acschembio.8b00124. Epub 2018 Jun 1. ACS Chem Biol. 2018. PMID: 29775273 Review.
Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.
Ishizawa J, Zarabi SF, Davis RE, Halgas O, Nii T, Jitkova Y, Zhao R, St-Germain J, Heese LE, Egan G, Ruvolo VR, Barghout SH, Nishida Y, Hurren R, Ma W, Gronda M, Link T, Wong K, Mabanglo M, Kojima K, Borthakur G, MacLean N, Ma MCJ, Leber AB, Minden MD, Houry W, Kantarjian H, Stogniew M, Raught B, Pai EF, Schimmer AD, Andreeff M. Ishizawa J, et al. Cancer Cell. 2019 May 13;35(5):721-737.e9. doi: 10.1016/j.ccell.2019.03.014. Epub 2019 May 2. Cancer Cell. 2019. PMID: 31056398
Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues.
Graves PR, Aponte-Collazo LJ, Fennell EMJ, Graves AC, Hale AE, Dicheva N, Herring LE, Gilbert TSK, East MP, McDonald IM, Lockett MR, Ashamalla H, Moorman NJ, Karanewsky DS, Iwanowicz EJ, Holmuhamedov E, Graves LM. Graves PR, et al. ACS Chem Biol. 2019 May 17;14(5):1020-1029. doi: 10.1021/acschembio.9b00222. Epub 2019 May 1. ACS Chem Biol. 2019. PMID: 31021596 Free PMC article.
Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death.
Wong KS, Mabanglo MF, Seraphim TV, Mollica A, Mao YQ, Rizzolo K, Leung E, Moutaoufik MT, Hoell L, Phanse S, Goodreid J, Barbosa LRS, Ramos CHI, Babu M, Mennella V, Batey RA, Schimmer AD, Houry WA. Wong KS, et al. Cell Chem Biol. 2018 Aug 16;25(8):1017-1030.e9. doi: 10.1016/j.chembiol.2018.05.014. Epub 2018 Jun 28. Cell Chem Biol. 2018. PMID: 30126533 Free article.
Arginine phosphorylation marks proteins for degradation by a Clp protease.
Trentini DB, Suskiewicz MJ, Heuck A, Kurzbauer R, Deszcz L, Mechtler K, Clausen T. Trentini DB, et al. Nature. 2016 Nov 3;539(7627):48-53. doi: 10.1038/nature20122. Epub 2016 Oct 6. Nature. 2016. PMID: 27749819 Free PMC article.
Cryo-EM structure of the ClpXP protein degradation machinery.
Gatsogiannis C, Balogh D, Merino F, Sieber SA, Raunser S. Gatsogiannis C, et al. Nat Struct Mol Biol. 2019 Oct;26(10):946-954. doi: 10.1038/s41594-019-0304-0. Epub 2019 Oct 3. Nat Struct Mol Biol. 2019. PMID: 31582852
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