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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 3
1964 1
1982 13
1983 44
1984 54
1985 58
1986 49
1987 46
1988 37
1989 42
1990 37
1991 20
1992 11
1993 11
1994 65
1995 131
1996 139
1997 192
1998 214
1999 216
2000 287
2001 315
2002 326
2003 388
2004 458
2005 438
2006 488
2007 533
2008 591
2009 589
2010 610
2011 668
2012 672
2013 687
2014 735
2015 754
2016 717
2017 654
2018 603
2019 261
2020 5
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11,132 results
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Page 1
ESCRT-dependent cargo sorting at multivesicular endosomes.
Frankel EB and Audhya A. Semin Cell Dev Biol 2018 - Review. PMID 28797838 Free PMC article.
The endosomal sorting complex required for transport (ESCRT) machinery is composed of five multi-subunit protein complexes, which act cooperatively at specialized endosomes to facilitate the movement of specific cargoes from the limiting membrane into vesicles that bud into the endosome lumen. ...Here, we discuss the potential roles that the ESCRT machinery plays during cargo sorting at multivesicular endosomes (MVEs)....
The endosomal sorting complex required for transport (ESCRT) machinery is composed of five multi-subunit protein complexes, which act cooper …
Rab GTPase Function in Endosome and Lysosome Biogenesis
Langemeyer L, et al. Trends Cell Biol 2018 - Review. PMID 30025982
In this review, we focus primarily on the role of the small Rab GTPases Rab5 and Rab7 as organelle markers and interactors of multiple effectors on endosomes and lysosomes and highlight their role in membrane dynamics, particularly fusion along the endolysosomal pathway....
In this review, we focus primarily on the role of the small Rab GTPases Rab5 and Rab7 as organelle markers and interactors of multiple effec …
Endosome maturation, transport and functions
Scott CC, et al. Semin Cell Dev Biol 2014 - Review. PMID 24709024
The early endosome receives all manner of incoming material from the plasma membrane, as well as from the Golgi, and serves as an initial sorting nexus routing molecules back to the cell surface through recycling endosomes, to the trans-Golgi network by retrograde transport, or on to the late endosome/lysosome. ...These multivesicular regions detach or mature from early endosomes and become free endocytic carrier vesicle/multivesicular body, which transports cargoes to late endosomes. ...
The early endosome receives all manner of incoming material from the plasma membrane, as well as from the Golgi, and serves as an initial so …
Recycling endosomes.
Goldenring JR. Curr Opin Cell Biol 2015 - Review. PMID 26022676 Free PMC article.
Endosomal receptor trafficking: Retromer and beyond
Wang J, et al. Traffic 2018 - Review. PMID 29667289 Free PMC article.
The mechanism by which SNX17 cargoes are recycled out of the endosomal system was demonstrated to involve a retromer-like complex termed the retriever, which is recruited to WASH positive endosomes through an interaction with the COMMD/CCDC22/CCDC93 (CCC) complex. ...
The mechanism by which SNX17 cargoes are recycled out of the endosomal system was demonstrated to involve a retromer-like complex termed the …
Endosomal Retrieval of Cargo: Retromer Is Not Alone
McNally KE and Cullen PJ. Trends Cell Biol 2018 - Review. PMID 30072228
Endosomes are major protein sorting stations in cells. Endosomally localised multi-protein complexes sort integral proteins, including signaling receptors, nutrient transporters, adhesion molecules, and lysosomal hydrolase receptors, for lysosomal degradation or conversely for retrieval and subsequent recycling to various membrane compartments. ...
Endosomes are major protein sorting stations in cells. Endosomally localised multi-protein complexes sort integral proteins, includin
Therapeutic Targeting of Endosomal G-Protein-Coupled Receptors
Thomsen ARB, et al. Trends Pharmacol Sci 2018 - Review. PMID 30180973 Free PMC article.
Emerging evidence indicates that GPCRs can continue to signal from endosomes by G-protein- and βARR-dependent processes. By regulating the duration and location of intracellular signaling events, GPCRs in endosomes control critically important processes, including gene transcription and ion channel activity. Thus, GPCRs in endosomes, in addition to at the cell surface, have emerged as important therapeutic targets....
Emerging evidence indicates that GPCRs can continue to signal from endosomes by G-protein- and βARR-dependent processes. By regulatin …
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