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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 13
1988 16
1989 38
1990 44
1991 33
1992 69
1993 78
1994 81
1995 116
1996 101
1997 135
1998 144
1999 111
2000 136
2001 141
2002 141
2003 159
2004 108
2005 78
2006 90
2007 68
2008 67
2009 62
2010 47
2011 37
2012 48
2013 40
2014 31
2015 25
2016 23
2017 17
2018 12
2019 3
2020 0
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2,228 results
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Page 1
MST kinases in development and disease
Thompson BJ and Sahai E. J Cell Biol 2015 - Review. PMID 26370497 Free PMC article.
The multifunctional role and therapeutic potential of HO-1 in the vascular endothelium.
Calay D and Mason JC. Antioxid Redox Signal 2014 - Review. PMID 24131232
In the vasculature, particular interest has focused on antioxidant and anti-inflammatory properties of the inducible HO-1 isoform in the vascular endothelium. ...RECENT ADVANCES: The understanding of the molecular basis for the regulation and functions of HO-1 has led to the identification of a variety of drugs that increase HO-1 activity in the vascular endothelium. ...
In the vasculature, particular interest has focused on antioxidant and anti-inflammatory properties of the inducible HO-1 isoform in the …
Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide.
Shibuya N, et al. J Biochem 2009. PMID 19605461
Both 3MST and CAT were localized to endothelium. Lysates of vascular endothelial cells produced H(2)S from cysteine and alpha-ketoglutarate. The present study provides a new insight into the production and release of H(2)S as a smooth muscle relaxant from vascular endothelium....
Both 3MST and CAT were localized to endothelium. Lysates of vascular endothelial cells produced H(2)S from cysteine and alpha- …
Endothelial p110γPI3K Mediates Endothelial Regeneration and Vascular Repair After Inflammatory Vascular Injury.
Huang X, et al. Circulation 2016. PMID 26839042 Free PMC article.
BACKGROUND: The integrity of endothelial monolayer is a sine qua non for vascular homeostasis and maintenance of tissue-fluid balance. However, little is known about the signaling pathways regulating regeneration of the endothelial barrier after inflammatory vascular injury. ...
BACKGROUND: The integrity of endothelial monolayer is a sine qua non for vascular homeostasis and maintenance of tissue-fluid balance …
The endothelial cyclooxygenase pathway: Insights from mouse arteries
Luo W, et al. Eur J Pharmacol 2016 - Review. PMID 27020548
However, results from our studies and those of others using similar mouse models suggest that COX-1 is the major functional isoform in vascular endothelium. ...Therefore, evidence that supports a role for COX-1 as the major mediator of PGI2 synthesis in mouse vascular endothelium, reasons for the inconsistency, and results that elucidate underlying mechanisms for divergent vasomotor reactions to endothelial COX activation will be discussed in this review. ...
However, results from our studies and those of others using similar mouse models suggest that COX-1 is the major functional isoform in va
Homocysteine catabolism: levels of 3 enzymes in cultured human vascular endothelium and their relevance to vascular disease.
Wang J, et al. Atherosclerosis 1992. PMID 1445498
They suggest that persons who are deficient in cystathionine beta-synthase or 5-methyltetrahydrofolate:homocysteine methyltransferase activity may not only develop homocysteinemia, but also have vascular endothelium which is more susceptible to damage by homocysteine than persons with normal enzyme levels....
They suggest that persons who are deficient in cystathionine beta-synthase or 5-methyltetrahydrofolate:homocysteine methyltransferase activi …
[Nitric oxide in vascular endothelium: control of production and mechanisms of action].
Gaynullina DK, et al. Usp Fiziol Nauk 2013 - Review. PMID 25438564 Russian.
The physiological mechanisms activating NO-synthase in endothelial cells and key targets of NO-pathway in vascular smoth muscle cells are reviewed as well....
The physiological mechanisms activating NO-synthase in endothelial cells and key targets of NO-pathway in vascular smoth muscle cells …
Arginase and vascular aging.
Santhanam L, et al. J Appl Physiol (1985) 2008 - Review. PMID 18719233 Free PMC article.
Vascular and associated ventricular stiffness is one of the hallmarks of the aging cardiovascular system. Both an increase in reactive oxygen species production and a decrease in nitric oxide (NO) bioavailability contribute to the endothelial dysfunction that underlies this vascular stiffness, independent of other age-related vascular pathologies such as atherosclerosis. ...The S-nitrosylation is mediated by the induction of NOS2 in the endothelium. Furthermore, arginase activation contributes to aging-related vascular changes by mechanisms that are not directly related to changes in NO signaling, including polyamine-dependent vascular smooth muscle proliferation and collagen synthesis. ...
Vascular and associated ventricular stiffness is one of the hallmarks of the aging cardiovascular system. Both an increase in reactiv
Regulation of pulmonary endothelial barrier function by kinases
Barabutis N, et al. Am J Physiol Lung Cell Mol Physiol 2016 - Review. PMID 27663990 Free PMC article.
The pulmonary endothelium is the target of continuous physiological and pathological stimuli that affect its crucial barrier function. ...
The pulmonary endothelium is the target of continuous physiological and pathological stimuli that affect its crucial barrier function …
Roles of the epoxygenase CYP2J2 in the endothelium.
Askari A, et al. Prostaglandins Other Lipid Mediat 2013 - Review. PMID 23474289 Free PMC article.
CYP2J2 is highly expressed in cardiovascular tissue including the heart and vascular endothelial cells. CYP2J2 and the EETs it produces have been shown to have a diverse range of effects on the vasculature, including the regulation of inflammation, vascular tone, cellular proliferation, angiogenesis, and metabolism. This review will examine these established and emerging roles of CYP2J2 in the biology of vascular endothelial cells....
CYP2J2 is highly expressed in cardiovascular tissue including the heart and vascular endothelial cells. CYP2J2 and the EETs it produc …
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