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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1966 1
1967 1
1968 1
1976 1
1980 1
1981 2
1983 2
1985 1
1986 1
1987 137
1988 423
1989 598
1990 675
1991 739
1992 892
1993 992
1994 1021
1995 1196
1996 1185
1997 1316
1998 1334
1999 1403
2000 1608
2001 1746
2002 1932
2003 1956
2004 1488
2005 1314
2006 1278
2007 1186
2008 1225
2009 1241
2010 1264
2011 1262
2012 1214
2013 1228
2014 1067
2015 1055
2016 868
2017 809
2018 713
2019 305
2020 2
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34,313 results
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Page 1
Emerging Roles of Vascular Endothelium in Metabolic Homeostasis.
Pi X, et al. Circ Res 2018 - Review. PMID 30355249 Free PMC article.
The close anatomic relationship between vascular endothelium and highly vascularized metabolic organs/tissues suggests that the crosstalk between ECs and these organs is vital for both vascular and metabolic homeostasis. ...Emerging data suggest that the vascular endothelium plays an unexpected role in the regulation of metabolic homeostasis and that endothelial dysregulation directly contributes to the development of metabolic disorders. ...
The close anatomic relationship between vascular endothelium and highly vascularized metabolic organs/tissues suggests that th …
Effects of shear stress on endothelial cells: go with the flow
Chistiakov DA, et al. Acta Physiol (Oxf) 2017 - Review. PMID 27246807
Haemodynamic forces influence the functional properties of vascular endothelium. Endothelial cells (ECs) have a variety of receptors, which sense flow and transmit mechanical signals through mechanosensitive signalling pathways to recipient molecules that lead to phenotypic and functional changes. ...Indeed, various flow patterns contribute to phenotypic and functional heterogeneity of arterial endothelium whose response to proatherogenic stimuli is differentiated. ...
Haemodynamic forces influence the functional properties of vascular endothelium. Endothelial cells (ECs) have a variety of rec …
Endothelial Glycocalyx and Cardiopulmonary Bypass
Myers GJ and Wegner J. J Extra Corpor Technol 2017 - Review. PMID 28979041 Free PMC article.
Studies of an intact endothelial glycocalyx layer (EGL) have revealed a number of critical functions that relate the importance of this protective layer to vascular integrity and permeability. These functions include the following: stabilization and maintenance of the vascular endothelium, an active reservoir of essential plasma proteins (i.e., albumin, antithrombin, heparan sulfate, and antioxidants), a buffer zone between the blood (formed elements) and the surface of the endothelium, and a mechanotransducer to detect changes in shear stress that facilitate vascular tone. ...
Studies of an intact endothelial glycocalyx layer (EGL) have revealed a number of critical functions that relate the importance of this prot …
Nanomechanics of vascular endothelium.
Fels J, et al. Cell Tissue Res 2014 - Review. PMID 24643677 Free PMC article.
There is accumulating evidence that endothelial nanomechanics of these individual compartments control vascular physiology. Depending on protein composition, filament formation and interaction with cross-linker proteins, these four compartments determine endothelial stiffness. ...This review will focus on endothelial nanomechanics and its impact on vascular function....
There is accumulating evidence that endothelial nanomechanics of these individual compartments control vascular physiology. Depending …
Endothelial cell functions
Michiels C. J Cell Physiol 2003 - Review. PMID 12891700
Hence, it participates to all aspects of the vascular homeostasis but also to physiological or pathological processes like thrombosis, inflammation, or vascular wall remodeling. Some of the most important endothelial functions will be described in the following review and more specifically, their role in blood vessel formation, in coagulation and fibribolysis, in the regulation of vascular tone as well as their participation in inflammatory reactions and in tumor neoangiogenesis....
Hence, it participates to all aspects of the vascular homeostasis but also to physiological or pathological processes like thrombosis …
Posttranscriptional adaptations of the vascular endothelium to hypoxia.
Ho JJ and Marsden PA. Curr Opin Hematol 2015 - Review. PMID 25767954
RECENT FINDINGS: Recent studies have revealed two emerging themes that are critical to endothelial/vascular biology and function. ...SUMMARY: Taken together, these findings bear significant diagnostic and therapeutic implications for vascular disease....
RECENT FINDINGS: Recent studies have revealed two emerging themes that are critical to endothelial/vascular biology and function. ... …
EDH: endothelium-dependent hyperpolarization and microvascular signalling.
Garland CJ and Dora KA. Acta Physiol (Oxf) 2017 - Review. PMID 26752699
Endothelium-dependent hyperpolarizing factor (EDHF) is a powerful vasodilator influence in small resistance arteries and thus an important modulator of blood pressure and flow. ...However, this idea has evolved with the recognition that a factor can operate alongside the spread of hyperpolarizing current from the endothelium to the vascular smooth muscle (VSM). ...
Endothelium-dependent hyperpolarizing factor (EDHF) is a powerful vasodilator influence in small resistance arteries and thus an impo
Cross-Talk Between Adipose Tissue Health, Myocardial Metabolism and Vascular Function: The Adipose-Myocardial and Adipose-Vascular Axes.
Iozzo P and Guzzardi MA. Curr Pharm Des 2016 - Review. PMID 26548309
Adipose tissue plays a fundamental role in the modulation and selection of nutrients reaching the myocardium, and adipocytes secrete adipokines and other molecules affecting myocardial metabolism and regulating vascular function. ...This review addresses the reciprocal interaction linking adipose tissue to myocardial metabolism and vascular function. We summarize evidence of factors released by adipose tissue that affect cardiac metabolism and vice versa. ...
Adipose tissue plays a fundamental role in the modulation and selection of nutrients reaching the myocardium, and adipocytes secrete adipoki …
Context-dependent function of ROS in the vascular endothelium: The role of the Notch pathway and shear stress.
Vieceli Dalla Sega F, et al. Biofactors 2017 - Review. PMID 28419584
The maintenance of a healthy endothelium depends on many factors and on their reciprocal interactions; in this framework, the Notch pathway and shear stress (SS) play two lead roles. ...
The maintenance of a healthy endothelium depends on many factors and on their reciprocal interactions; in this framework, the Notch p …
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