"Epilepsia Open"[Journal] - Search Results

Year	Number of Results
2016	25
2017	60
2018	89
2019	76
2020	67
2021	113
2022	122
2023	203
2024	260
2025	256
2026	118

1

Transcriptional signatures of cortical morphometric variability in temporal lobe epilepsy.

Dong Y, Wang S, Luo J, Meng J, Liu Y, Zhang S. Dong Y, et al. Epilepsia Open. 2026 Jul 9. doi: 10.1002/epi4.70306. Online ahead of print. Epilepsia Open. 2026. PMID: 42423494 Free article.

2

Rest-activity patterns across development in two mouse models of autism and epilepsy.

Dash I, Fredlund F, Wickham J, Andersson M, Ekdahl CT. Dash I, et al. Epilepsia Open. 2026 Jul 4. doi: 10.1002/epi4.70250. Online ahead of print. Epilepsia Open. 2026. PMID: 42400446 Free article.

3

Utility of repeat stereotactic EEG in pediatric patients with tuberous sclerosis.

Uchitel J, Fariyike O, Steeman S, Rockwood S, Kim LH, Choi J, Hengartner AC, Fel AH, Teeyagura P, Grant G, Buch V, Mahaney KB, Prolo LM, Hyslop Segeren A, Phillips HW. Uchitel J, et al. Epilepsia Open. 2026 Jul 4. doi: 10.1002/epi4.70293. Online ahead of print. Epilepsia Open. 2026. PMID: 42400368 Free article.

4

Expanding the electroclinical spectrum of TANC2-related disorders: Lennox-Gastaut syndrome and related developmental epileptic phenotypes.

Perilli L, Stipa C, Villano G, Licchetta L, Strothmann L, Jauss RT, Kluger GJ, Minardi R; NETRE consortium; Gobbi G, Grosso S, Bisulli F, Striano P. Perilli L, et al. Epilepsia Open. 2026 Jul 3. doi: 10.1002/epi4.70303. Online ahead of print. Epilepsia Open. 2026. PMID: 42397682 Free article.

5

Real-world use of Cenobamate in pediatric drug-resistant epilepsy: A European multicenter retrospective study.

Makridis KL, Bast T, Auvin S, Krsek P, Ebel M, Breuer E, Beckhaus M, Bašovský M, Danhofer P, Horák O, Orsini A, Ramos Rivera GA, Medřická H, Syrbe S, Kaindl AM. Makridis KL, et al. Epilepsia Open. 2026 Jul 3. doi: 10.1002/epi4.70301. Online ahead of print. Epilepsia Open. 2026. PMID: 42397117 Free article.

6

Polypharmacy burden and incident epilepsy among older adults in the United States.

Shearn-Nance G, Vu L, Fein HL, Bensken WP, Rieke JG, Sajatovic M, Ghearing G, Warner DF, Koroukian SM, Schiltz NK. Shearn-Nance G, et al. Epilepsia Open. 2026 Jul 2. doi: 10.1002/epi4.70300. Online ahead of print. Epilepsia Open. 2026. PMID: 42390713 Free article.

7

Relative entropy as a biomarker for vagus nerve stimulation response in epilepsy: Insights from intracerebral electroencephalography.

Erben Š, Cimbálník J, Zatloukalová E, Búřilová P, Vinklárek J, Sklenárová B, Chrastina J, Brichtová E, Kočvarová J, Strýček O, Pail M, Brázdil M, Doležalová I. Erben Š, et al. Epilepsia Open. 2026 Jun 30. doi: 10.1002/epi4.70297. Online ahead of print. Epilepsia Open. 2026. PMID: 42378010 Free article.

8

Characteristics and long-term outcomes of children with confirmed focal cortical dysplasia type 1 after epilepsy surgery: A population-based study.

Zheng V, Koroknay-Pál P, Lehtinen H, Gaily E, Karppinen A, Paetau A, Tynninen O, Leinonen H, Laakso A, Metsähonkala EL. Zheng V, et al. Epilepsia Open. 2026 Jun 20. doi: 10.1002/epi4.70296. Online ahead of print. Epilepsia Open. 2026. PMID: 42322240 Free article.

9

Real-world effectiveness of cenobamate in drug-resistant and ultra-refractory epilepsy: A multicenter study.

Strýček O, Amlerová J, Pail M, Kočvarová J, Slonková J, Šimčík M, Stanzelová K, Šibalová M, Marusič P, Brázdil M. Strýček O, et al. Epilepsia Open. 2026 Jun 18. doi: 10.1002/epi4.70298. Online ahead of print. Epilepsia Open. 2026. PMID: 42313398 Free article.

10

A first in disease trial of the safety, tolerability, and anti-seizure effects of ES-481 in drug-resistant epilepsy.

Foster EC, Millist L, Germaine J, Chamorro S, Roberts C, Nicolo JP, Hosking S, Perucca P, Mullen S, Robinson H, Wharrie R, Walsh B, Reutens D, Irwin K, Zeng H, Niecestro R, O'Brien TJ. Foster EC, et al. Epilepsia Open. 2026 Jun 18. doi: 10.1002/epi4.70294. Online ahead of print. Epilepsia Open. 2026. PMID: 42312676 Free article.

11

Pulse-based photoplethysmography quality assessment improves wearable seizure detection performance.

Shahbakhti M, Bosch AT, Long X, van Dijk JP, Thijs RD. Shahbakhti M, et al. Epilepsia Open. 2026 Jun 17. doi: 10.1002/epi4.70242. Online ahead of print. Epilepsia Open. 2026. PMID: 42305102 Free article.

12

Lipid-based Nano-delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges.

Varshini PK, Divya A, Sowndharya K, Jeevitha P, Manoj S, Rahman A, Ahamed A, Abirahul R, Subash P, Khute S. Varshini PK, et al. Epilepsia Open. 2026 Jun 16. doi: 10.1002/epi4.13137. Online ahead of print. Epilepsia Open. 2026. PMID: 42303582 Free article. Review.

13

Smartphone videos for infantile epileptic spasms triaging and assessment (VISTA study): Impact of education and standardized clinical history on diagnostic accuracy.

Shrock CL, Savage MC, Sham L, Cortina C, Gray KP, Lee IH, Triki CC, French J, Cross JH, Devinsky O, Wilmshurst JM, Patel AA. Shrock CL, et al. Epilepsia Open. 2026 Jun 12. doi: 10.1002/epi4.70292. Online ahead of print. Epilepsia Open. 2026. PMID: 42283429 Free article.

14

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3^+/D120N mouse model of Lennox-Gastaut syndrome.

Harman T, Sharman LA, Yip KL, Bedoya-Pérez M, Janve V, Arnold JC. Harman T, et al. Epilepsia Open. 2026 Jun 11. doi: 10.1002/epi4.70289. Online ahead of print. Epilepsia Open. 2026. PMID: 42274296 Free article.

15

Occurrence and clinical correlates of depressive symptoms in adults with epilepsy: A study in Georgia.

Silagadze K, Burkadze E, Areshidze M, Silagadze T, Kasradze S, Sander JW. Silagadze K, et al. Epilepsia Open. 2026 Jun 8. doi: 10.1002/epi4.70291. Online ahead of print. Epilepsia Open. 2026. PMID: 42257684 Free article.

16

Hypersensitivity reaction risk when restarting cenobamate after discontinuation: Insights from a prolonged hospitalized cohort.

Feldman M, Alexopoulos A, Bulacio J, Nair D, Punia V. Feldman M, et al. Epilepsia Open. 2026 Jun 5. doi: 10.1002/epi4.70288. Online ahead of print. Epilepsia Open. 2026. PMID: 42246692 Free article.

17

Beyond seizures: A multidimensional approach to non-seizure issues in Lennox-Gastaut syndrome. Insights from Italian experts.

Di Gennaro G, Battaglia DI, Bonanni P, Duma GM, Coppola A, Ferlazzo E, Pruna D, Di Bonaventura C. Di Gennaro G, et al. Epilepsia Open. 2026 Jun 4. doi: 10.1002/epi4.70290. Online ahead of print. Epilepsia Open. 2026. PMID: 42237860 Free article. Review.

18

Perampanel as add-on in high-grade glioma-related epilepsy: Seizure control and QoL in a prospective, multicenter, real-world 6-month follow-up study.

Impellizzeri M, Paone P, Pauletto G, Nilo A, Beretta S, Salmaggi A, Consoli S, Quadri S. Impellizzeri M, et al. Epilepsia Open. 2026 Jun 4. doi: 10.1002/epi4.70274. Online ahead of print. Epilepsia Open. 2026. PMID: 42237784 Free article.

19

On-site exposure to clinical epilepsy practice for experimental scientists engaged in epilepsy research: A pilot study by the ILAE commission on neurobiology.

de Curtis M, Battaglia G, Aguado-Carrillo G, Aronica E, Asukile M, Balestrini S, Barba C, Baumgartner T, Becker AJ, Bisulli F, Braga P, Carcak N, Cavalheiro E, Delanty N, Ferri L, Friedman A, Friedman D, Galovic M, Gelinas JN, Giagante B, Henriquez-Ch R, Kander V, Kochen S, Krysl D, Kudr M, Ikeda A, Legnani M, Lin Y, Martinez-Juarez I, Muccioli L, Mwendaweli N, Oddo S, Özkara Ç, Peixoto-Santos JE, Perucca P, Potschka H, Rocha L, Scharfman H, Scheffer IE, Surges R, Triki CC, Uribe-San-Martin R, Valente K, van Vliet EA, Wang Y, Whatley B, Wilmshurst JM, Yacubian EM, De Rossi A, de Curtis S, Jiruska P, Henshall DC. de Curtis M, et al. Epilepsia Open. 2026 Jun 1. doi: 10.1002/epi4.70282. Online ahead of print. Epilepsia Open. 2026. PMID: 42220231 Free article.

20

Real-world-data for phenotypes and genotypes of rare monogenic genetic epilepsies and genes of uncertain significance for epilepsy.

Morris H, Mathew E, Bahl S, Villa-Lopez M, Mercimek-Andrews S. Morris H, et al. Epilepsia Open. 2026 Jun 1. doi: 10.1002/epi4.70269. Online ahead of print. Epilepsia Open. 2026. PMID: 42220229 Free article.

21

Postmortem MRI reveals distinct structural features in sudden unexpected death in epilepsy.

Hill A, Xiao F, Thom M, Maudgil D, Bergman H, Duncan JS, Arthurs OJ, Sander JW, Diehl B, Koepp MJ. Hill A, et al. Epilepsia Open. 2026 Jun;11(3):1054-1060. doi: 10.1002/epi4.70276. Epub 2026 May 8. Epilepsia Open. 2026. PMID: 42101226 Free PMC article.

22

Artificial intelligence in the assessment of epilepsy-related genetic mutations: Learned from GABA_A receptors and GABA transporter 1.

Wang J, Kang JQ. Wang J, et al. Epilepsia Open. 2026 Jun;11(3):740-751. doi: 10.1002/epi4.70259. Epub 2026 May 8. Epilepsia Open. 2026. PMID: 42101103 Free PMC article. Review.

23

KCNQ2 neonatal epilepsy: Impact of prompt diagnosis and treatment, and early predictors of outcome severity.

Jadhav T, Bouffler SE, Innes E, Fahey M, Hunter M, Kothur K, Lunke S, Lynch M, Macdonald-Laurs E, Palmer EE, Patel C, Pinner J, Riney K, Sachdev R, Sandaradura SA, Scheffer IE, Stark Z, Howell KB. Jadhav T, et al. Epilepsia Open. 2026 Jun;11(3):949-961. doi: 10.1002/epi4.70266. Epub 2026 May 4. Epilepsia Open. 2026. PMID: 42081271 Free PMC article.

24

Neuroanatomical correlates of neuropsychological dysfunction in pediatric pharmacoresistant epilepsy due to focal cortical dysplasia type II.

Arenivas A, Morris S, Lapin B, Li Y, Ferguson L, Jones SE, Blümcke I, Najm I, Busch RM, Wang ZI. Arenivas A, et al. Epilepsia Open. 2026 Jun;11(3):1003-1016. doi: 10.1002/epi4.70268. Epub 2026 Apr 30. Epilepsia Open. 2026. PMID: 42057689 Free PMC article.

25

Trends in antiseizure medication monotherapy for pediatric epilepsy in the United States.

Ostendorf AP, Eisner M, Abdel-Rasoul M, Ahrens SM, Twanow JD, Goodkin HP, Beatty CW. Ostendorf AP, et al. Epilepsia Open. 2026 Jun;11(3):1028-1035. doi: 10.1002/epi4.70273. Epub 2026 Apr 29. Epilepsia Open. 2026. PMID: 42052958 Free PMC article.

26

Energy metabolism, adenosine, and glutamate signaling reprogramming by decanoic acid in Glut1 disorder syndrome.

Pain E, Kapatel Y, Singh PK, Jones KL, Selvakumaran J, Malerba A, Lucchesi W, Rutherford T, Gurnett CA, Walker MC, Williams RSB. Pain E, et al. Epilepsia Open. 2026 Jun;11(3):1036-1045. doi: 10.1002/epi4.70263. Epub 2026 Apr 28. Epilepsia Open. 2026. PMID: 42047543 Free PMC article.

27

Widening participation in the International League Against Epilepsy: Looking to the future.

Cross JH, Coleman L, Oritz S, Ivaniuk A, Nome CG, Roza E, Shafer PO, von Gaudecker J, Ryan C, Brinkmann BH, Neuray C, Welty T, Wiebe S, Guekht A. Cross JH, et al. Epilepsia Open. 2026 Jun;11(3):719-726. doi: 10.1002/epi4.70272. Epub 2026 Apr 28. Epilepsia Open. 2026. PMID: 42047531 Free PMC article.

28

MiR-30a-5p mediates epileptogenesis in epilepsy models by targeting SOX4 to regulate the Wnt/β-catenin pathway.

Yang Z, Zhang X, Guo J, Wei Y, Li J. Yang Z, et al. Epilepsia Open. 2026 Jun;11(3):983-1002. doi: 10.1002/epi4.70270. Epub 2026 Apr 24. Epilepsia Open. 2026. PMID: 42029101 Free PMC article.

29

Chronic sleep deprivation promotes drug-resistant epilepsy via the BMAL1-mTOR-P-gp axis.

Wang X, Li R, Zhang Y, Hu Y, Chen J, Tian S, Zhou D, Chi X. Wang X, et al. Epilepsia Open. 2026 Jun;11(3):1017-1027. doi: 10.1002/epi4.70271. Epub 2026 Apr 20. Epilepsia Open. 2026. PMID: 42011054 Free PMC article.

30

Real-world effectiveness of highly purified cannabidiol in epilepsy associated with 15q11.2-q13.1 duplication and deletion syndromes: A multicenter study.

Cerulli Irelli E, Mazzeo A, Perulli M, Ramantani G, Battaglia D, Bagnasco I, Cognolato E, Striano P, Negrin S, Danieli A, Bonanni P, Operto FF, Di Bonaventura C, Coppola A, Orsini A. Cerulli Irelli E, et al. Epilepsia Open. 2026 Jun;11(3):1046-1053. doi: 10.1002/epi4.70241. Epub 2026 Apr 16. Epilepsia Open. 2026. PMID: 41992447 Free PMC article.

31

The Global Epilepsy Needs Study (GENS): A mixed-methods, multi-country exploration of the unmet psychosocial and everyday needs of people with epilepsy.

Baker GA, Bagga SK, Walsh D, Nolan C, Sharma S, Hooker C, Gonzalez Parrao P, Sofia F, Cross JH, Bertone MM, García I, Janneh AJ, Kukla A, Montero EV, Ding D, Friedrich L, Pinto LF, Singh G, Triki CC, Raj L, Reese A; GENS Collaborators. Baker GA, et al. Epilepsia Open. 2026 Jun;11(3):814-832. doi: 10.1002/epi4.70237. Epub 2026 Apr 15. Epilepsia Open. 2026. PMID: 41984448 Free PMC article.

32

ILAE-YES global webinar series: Integrating clinical and basic science in epilepsy research.

Nome CG, Ravat P, Bartolomei F, de Curtis M, Di Sapia R, Galovic M, Gogou M, Imbach L, Jacobs J, Kobow K, Lam AD, Lisgaras CP, Micalizzi E, Nikalexi E, Noebels JL, Paz JT, Roopra AS, Shaaban S, Sheybani L, Sivathamboo S, Marti AS, Williamson A, Kuroda N. Nome CG, et al. Epilepsia Open. 2026 Jun;11(3):710-718. doi: 10.1002/epi4.70267. Epub 2026 Apr 14. Epilepsia Open. 2026. PMID: 41980698 Free PMC article.

33

The future of epilepsy care in the United Kingdom: A roadmap for technology-enabled transformation.

Terry JR, Shankar R. Terry JR, et al. Epilepsia Open. 2026 Jun;11(3):727-739. doi: 10.1002/epi4.70262. Epub 2026 Apr 11. Epilepsia Open. 2026. PMID: 41964582 Free PMC article. Review.

34

Incidence and outcomes of childhood status epilepticus in Kano, northern Nigeria.

Sabo UA, Kabir H, Abdullahi AT, Adamu H, Salihu AS, Abdullahi AM, Wada A, Iliyasu Z, Zakari J, Gambo S, Jibir BW, Aliyu MH, Wudil UJ, Ingles DJ, Prigmore HL, Shepherd BE, Paolucci AR, Trevathan E. Sabo UA, et al. Epilepsia Open. 2026 Jun;11(3):973-982. doi: 10.1002/epi4.70265. Epub 2026 Apr 9. Epilepsia Open. 2026. PMID: 41955019 Free PMC article.

35

A multicenter, video-EEG-based validation of a multimodal wearable device for focal seizure detection in adults: The SeizeIT2 study.

Swinnen L, Bhagubai M, Chatzichristos C, Weber Y, Wolking S, Ermis U, Schriewer E, Schulze-Bonhage A, Dümpelmann M, Zabler N, Epitashvilli N, Mahler B, Sen A, Symmonds M, Richardson MP, Biondi A, Sales F, Sulaiman A 1st, De Vos M, Van Paesschen W. Swinnen L, et al. Epilepsia Open. 2026 Jun;11(3):883-894. doi: 10.1002/epi4.70260. Epub 2026 Apr 8. Epilepsia Open. 2026. PMID: 41949013 Free PMC article. Clinical Trial.

36

Global disparities in the recognition, diagnosis, and management of seizures or epilepsy of autoimmune etiology.

Guarasci E, Whitney R, Budhram A, Nabavi Nouri M. Guarasci E, et al. Epilepsia Open. 2026 Jun;11(3):922-934. doi: 10.1002/epi4.70256. Epub 2026 Apr 2. Epilepsia Open. 2026. PMID: 41924966 Free PMC article.

37

Effectiveness of adjunctive low-dose clobazam in adults with focal drug-resistant epilepsy and incomplete response to cenobamate: A real-world study.

Ciullo I, D'Aniello A, Panzini C, Salamone EM, Quarato PP, Grammaldo LG, Dal Pozzo M, Abeni D, Di Gennaro G. Ciullo I, et al. Epilepsia Open. 2026 Jun;11(3):962-972. doi: 10.1002/epi4.70261. Epub 2026 Apr 1. Epilepsia Open. 2026. PMID: 41919359 Free PMC article.

38

Expanding the scope of pediatric epilepsy surgery: Access, indications, and outcomes in a modern cohort.

McLaren JR, Muñoz W, Kwon H, Geffrey AL, Nanda P, Thibert R, Grossmann L, Stufflebeam S, Jaimes C, Emerton BC, Kahle KT, Richardson RM, Chu CJ. McLaren JR, et al. Epilepsia Open. 2026 Jun;11(3):935-948. doi: 10.1002/epi4.70257. Epub 2026 Mar 31. Epilepsia Open. 2026. PMID: 41915477 Free PMC article.

39

An iEEG investigation on sex-specific differences in seizure duration.

Albert I Gracenea P, Muss A, Seethaler M, Rémi J, Kaufmann E. Albert I Gracenea P, et al. Epilepsia Open. 2026 Jun;11(3):912-921. doi: 10.1002/epi4.70258. Epub 2026 Mar 30. Epilepsia Open. 2026. PMID: 41907014 Free PMC article.

40

Perspectives on the burden of drug-resistant epilepsy and treatment priorities: Findings from a multistakeholder survey.

Lattanzi S, Schmitz B, Canas N, Leach JP, Benoist C, Pierucci D, Álvarez-Barón E. Lattanzi S, et al. Epilepsia Open. 2026 Jun;11(3):787-800. doi: 10.1002/epi4.70226. Epub 2026 Mar 27. Epilepsia Open. 2026. PMID: 41891222 Free PMC article.

41

Integrative genomic and spatial transcriptomic analysis elucidates the oligodendrocyte-mediated etiology of epileptic cortical thinning.

Zhang D, Zhang Q, Li G, Yu L, Ma Y, Hong X, Kui Y, Cai S, Sun J, Zhu Z. Zhang D, et al. Epilepsia Open. 2026 Jun;11(3):895-911. doi: 10.1002/epi4.70251. Epub 2026 Mar 26. Epilepsia Open. 2026. PMID: 41885647 Free PMC article.

42

Evaluating the task-specificity model of verbal memory: Regional volumetric analyses in temporal lobe epilepsy with hippocampal sclerosis.

Sitoh A, Weintrob D, Anderson JFI, Pardoe HR, O'Shea MF, Jackson GD, Perucca P, Tailby C. Sitoh A, et al. Epilepsia Open. 2026 Jun;11(3):764-776. doi: 10.1002/epi4.70195. Epub 2026 Mar 26. Epilepsia Open. 2026. PMID: 41884995 Free PMC article.

43

Microelectrode array scaled for human hippocampal slices.

Pelkonen A, Lezhneva V, Ryynänen T, Kreutzer J, Sitnikova V, Gómez-Budia M, Della Pietra A, Dougalis A, Kyyriäinen J, Torkamani-Azar M, Eronen H, Rauramaa T, Immonen A, Leinonen V, Sierra A, Kälviäinen R, Malm T. Pelkonen A, et al. Epilepsia Open. 2026 Jun;11(3):777-786. doi: 10.1002/epi4.70204. Epub 2026 Mar 25. Epilepsia Open. 2026. PMID: 41879560 Free PMC article.

44

Does having bad epilepsy make you a good surgical candidate? A number needed to treat analysis.

Baxendale S, Heaney D, Walker MC. Baxendale S, et al. Epilepsia Open. 2026 Jun;11(3):692-701. doi: 10.1002/epi4.70212. Epub 2026 Mar 25. Epilepsia Open. 2026. PMID: 41879516 Free PMC article. Review.

45

ILAE dietary treatments task force special report: Maternal ketogenic diet exposure in epilepsy pregnancy registries-A call to action.

Kverneland M, De Giorgis V, Healy L, Faltersack K, McDonald TJW, Armeno M, Cervenka MC, Devlin A. Kverneland M, et al. Epilepsia Open. 2026 Jun;11(3):702-709. doi: 10.1002/epi4.70246. Epub 2026 Mar 25. Epilepsia Open. 2026. PMID: 41878801 Free PMC article.

46

Hypophosphatemia in the first seizure clinic: Data from a second UK center.

Atkinson T, Grundmann A, Thomas RH. Atkinson T, et al. Epilepsia Open. 2026 Jun;11(3):1063-1064. doi: 10.1002/epi4.70253. Epub 2026 Mar 23. Epilepsia Open. 2026. PMID: 41870008 Free PMC article. No abstract available.

47

Incorporation bias in clinical prediction models for epilepsy.

Kampman SL, Neijzen RL, Braun KPJ, van der Salm SMA, Otte WM. Kampman SL, et al. Epilepsia Open. 2026 Jun;11(3):1061-1062. doi: 10.1002/epi4.70252. Epub 2026 Mar 23. Epilepsia Open. 2026. PMID: 41867141 Free PMC article. No abstract available.

48

Practical consensus recommendations for polytherapy involving stiripentol in Dravet syndrome: A nominal group approach.

Cross JH, Nabbout R, Gidal B, Sullivan J, Wirrell E. Cross JH, et al. Epilepsia Open. 2026 Jun;11(3):833-846. doi: 10.1002/epi4.70245. Epub 2026 Mar 18. Epilepsia Open. 2026. PMID: 41848774 Free PMC article.

49

Trajectories of quality of life, anxiety and depressive symptomatology, and health-related work productivity after first seizure events.

Foster E, Chen Z, Conquest A, Vaughan DN, Tailby C, Carney PW, D'Souza W, Au Yong HM, Nicolo JP, Pellinen J, Liew D, O'Brien TJ, Kwan P, Ademi Z. Foster E, et al. Epilepsia Open. 2026 Jun;11(3):859-870. doi: 10.1002/epi4.70249. Epub 2026 Mar 14. Epilepsia Open. 2026. PMID: 41830635 Free PMC article.

50

Prediction of treatment response in infantile epileptic spasms syndrome using EEG phase-amplitude coupling.

Mostaghimi S, Pinto-Orellana MA, Green N, Shrey DW, Miyakoshi M, Hussain SA, Lopour BA. Mostaghimi S, et al. Epilepsia Open. 2026 Jun;11(3):801-813. doi: 10.1002/epi4.70230. Epub 2026 Mar 14. Epilepsia Open. 2026. PMID: 41830626 Free PMC article.

51

"Not always the magic bullet"-Insufficient seizure control by ketogenic dietary therapies in Glut1 Deficiency Syndrome.

Klepper J, Runkel E, Kiesel L. Klepper J, et al. Epilepsia Open. 2026 Jun;11(3):847-858. doi: 10.1002/epi4.70243. Epub 2026 Mar 14. Epilepsia Open. 2026. PMID: 41830506 Free PMC article.

52

Relationship between hTERT levels and oxidative stress in epilepsy patients.

Üremiş MM, Tuncel Berktaş D, Üremiş N, İnanç Tolun F. Üremiş MM, et al. Epilepsia Open. 2026 Jun;11(3):752-763. doi: 10.1002/epi4.70165. Epub 2026 Mar 12. Epilepsia Open. 2026. PMID: 41818627 Free PMC article.

53

Diagnostic reassessment in patients previously diagnosed with childhood-onset epilepsy during the transition to adult care: A retrospective cohort study in a tertiary epilepsy center.

Fukuyama T, Nasuno M, Yabe M, Nishioka M, Hoshino Y, Natsume T, Kanaya K, Takano K, Kaneko T, Inoue Y. Fukuyama T, et al. Epilepsia Open. 2026 Jun;11(3):871-882. doi: 10.1002/epi4.70248. Epub 2026 Mar 10. Epilepsia Open. 2026. PMID: 41804683 Free PMC article.

54

A price check on the ketogenic diet for adults with epilepsy in Australia.

King L, Maccarrone J, Kaur A, Chen S, Kwan P, O'Brien TJ, Kaul N. King L, et al. Epilepsia Open. 2026 May 25. doi: 10.1002/epi4.70285. Online ahead of print. Epilepsia Open. 2026. PMID: 42184139 Free article.

55

Unveiling sleep disturbances in KCNB1-related disorders: Insights from a cohort of 78 individuals.

Scorrano G, Breuillard D, Thimon A, Chemaly N, Nabbout R. Scorrano G, et al. Epilepsia Open. 2026 May 21. doi: 10.1002/epi4.70247. Online ahead of print. Epilepsia Open. 2026. PMID: 42166541 Free article.

56

Progressive myoclonus epilepsy in Down syndrome with Alzheimer's disease: An 11-year longitudinal study and proposed diagnostic red flags.

d'Orsi G, Calò E, Di Claudio MT, Ferro CP, Costantino U, Perrone E, Latino RR. d'Orsi G, et al. Epilepsia Open. 2026 May 21. doi: 10.1002/epi4.70277. Online ahead of print. Epilepsia Open. 2026. PMID: 42166529 Free article.

57

Real-world outcomes of responsive neurostimulation in patients with Lennox-Gastaut syndrome: A multicenter retrospective study.

Swartwood SM, Bollo RJ, Chu CJ, Geffrey AL, Richardson RM, Nariai H, Fallah A, Ahn S, Ghatan S, Chenevert L, La Vega-Talbott M, Espinoza AC. Swartwood SM, et al. Epilepsia Open. 2026 May 15. doi: 10.1002/epi4.70283. Online ahead of print. Epilepsia Open. 2026. PMID: 42138251 Free article.

58

Ketogenic diet therapy for children with super-refractory status epilepticus in intensive care: International clinical practice recommendations.

Blackford R, Whiteley VJ, Hardy I, Armeno M, Bollard T, Cross JH, Eltze C, George S, Howard C, Nijstad AL, Talzzia E, Paget C, Ray S, Simpson Z, Song-Pozderac E, Szmurlo A, Tan-Smith C, Vanatta L, van der Louw E, Schoeler NE; Ketogenic Dietitians Research Network. Blackford R, et al. Epilepsia Open. 2026 May 14. doi: 10.1002/epi4.70284. Online ahead of print. Epilepsia Open. 2026. PMID: 42132666 Free article.

59

Impact of cenobamate on cortical responses to transcranial magnetic stimulation in people with drug-resistant focal epilepsy.

Gefferie SR, Jiménez-Jiménez D, Visser GH, Helling RM, van den Maagdenberg AMJM, Sander JW, Balestrini S, Thijs RD. Gefferie SR, et al. Epilepsia Open. 2026 May 14. doi: 10.1002/epi4.70255. Online ahead of print. Epilepsia Open. 2026. PMID: 42132132 Free article.

60

Fast sleep spindles as a potential prognostic marker of developmental outcome in infantile epileptic spasms syndrome.

Ohta K, Reuben T, Okanishi T, Yoshino G, Hosoda T, Okada K, Maegaki Y. Ohta K, et al. Epilepsia Open. 2026 May 12. doi: 10.1002/epi4.70278. Online ahead of print. Epilepsia Open. 2026. PMID: 42118062 Free article.

61

Effectiveness and safety of implantable vagus nerve stimulation in people with primary generalized tonic-clonic seizures.

Eggleston K, Curley J, Verner R, Dibue M, Gordon C, Giannicola G, Nichol K. Eggleston K, et al. Epilepsia Open. 2026 May 12. doi: 10.1002/epi4.70281. Online ahead of print. Epilepsia Open. 2026. PMID: 42117371 Free article.

62

Genetic landscape of patients with atypical absence status epilepticus: A systematic review.

Cioclu MC, Giovannini G, Meletti S. Cioclu MC, et al. Epilepsia Open. 2026 May 11. doi: 10.1002/epi4.70275. Online ahead of print. Epilepsia Open. 2026. PMID: 42112912 Free article. Review.

63

Characterizing electroencephalogram dynamics during sedation withdrawal: Insights into cortical recovery following status epilepticus.

Dhoisne M, Derambure P, Delval A, Nseir S, Betrouni N, Tortuyaux R. Dhoisne M, et al. Epilepsia Open. 2026 Apr;11(2):605-618. doi: 10.1002/epi4.70239. Epub 2026 Mar 8. Epilepsia Open. 2026. PMID: 41795786 Free PMC article.

64

Microstructure imaging in patients undergoing evaluation for epilepsy surgery or low-grade glioma: Clinical utility of a novel diffusion MRI method.

Grubor I, Serednicka K, Säll C, Strandberg MC, Nilsson M, Bengzon J. Grubor I, et al. Epilepsia Open. 2026 Apr;11(2):592-604. doi: 10.1002/epi4.70244. Epub 2026 Mar 6. Epilepsia Open. 2026. PMID: 41790434 Free PMC article.

65

What does it mean to live with epilepsy? Burden of illness from the patient perspective.

Wagner JM, Oak B, Smith B, Athavale A, Skaar JR, Ong A, Harden C. Wagner JM, et al. Epilepsia Open. 2026 Apr;11(2):452-465. doi: 10.1002/epi4.70222. Epub 2026 Mar 2. Epilepsia Open. 2026. PMID: 41770623 Free PMC article.

66

Fenfluramine in SCN1A-related GEFS+: A multicenter observational study on efficacy, EEG improvement, and tolerability.

Dell'Isola GB, Muda A, Giordano L, Guerrini R, Boncristiano A, Pietrafusa N, Polselli M, Bisulli F, Ragona F, Riva A, Striano P, Battaglia DI, Vigevano F. Dell'Isola GB, et al. Epilepsia Open. 2026 Apr;11(2):619-626. doi: 10.1002/epi4.70187. Epub 2026 Feb 25. Epilepsia Open. 2026. PMID: 41739881 Free PMC article.

67

Loss of cyclin-dependent kinase-like 5 results in susceptibility to audiogenic seizures in mice.

Higgins J, Egan S, El-Mansoury B, Henshall DC, Mamad O. Higgins J, et al. Epilepsia Open. 2026 Apr;11(2):670-678. doi: 10.1002/epi4.70240. Epub 2026 Feb 20. Epilepsia Open. 2026. PMID: 41718488 Free PMC article.

68

Safety of postimplantation MRI with Dixi microdeep electrodes in situ: An in vitro evaluation of MRI-related heating at 1.5T.

Tuura RO, Luechinger R, Heule R, Kottke R, Rona S, Krayenbühl N, Ramantani G. Tuura RO, et al. Epilepsia Open. 2026 Apr;11(2):553-563. doi: 10.1002/epi4.70238. Epub 2026 Feb 20. Epilepsia Open. 2026. PMID: 41718466 Free PMC article.

69

Structural brain imaging biomarkers for predicting seizure recurrence after a first unprovoked seizure.

Ooi S, Tailby C, Pardoe HR, Carney PW, Sethi M, Haderlein J, Jackson GD, Vaughan DN. Ooi S, et al. Epilepsia Open. 2026 Apr;11(2):538-552. doi: 10.1002/epi4.70236. Epub 2026 Feb 17. Epilepsia Open. 2026. PMID: 41701158 Free PMC article.

70

Out of the lab, into real life: Evaluating at-home EEG self-monitoring.

Cousyn L, Biondi A, Winston JS, McWilliam M, Viana PF, Schreuder M, Laiou P, Richardson MP. Cousyn L, et al. Epilepsia Open. 2026 Apr;11(2):663-669. doi: 10.1002/epi4.70235. Epub 2026 Feb 17. Epilepsia Open. 2026. PMID: 41701004 Free PMC article.

71

Automated analysis of postictal generalized electroencephalogram suppression for SUDEP risk stratification.

Reddy SD, Balasubramanian S, Ramakrishnan S, Reddy DS. Reddy SD, et al. Epilepsia Open. 2026 Apr;11(2):652-662. doi: 10.1002/epi4.70229. Epub 2026 Feb 17. Epilepsia Open. 2026. PMID: 41700807 Free PMC article.

72

Efficacy of neurosurgical interventions for epilepsy in polymicrogyria: A systematic review.

Rinella S, Lo Bianco M, Polizzi A, Ruggieri M, O'Callaghan FJK. Rinella S, et al. Epilepsia Open. 2026 Apr;11(2):390-408. doi: 10.1002/epi4.70217. Epub 2026 Feb 14. Epilepsia Open. 2026. PMID: 41689720 Free PMC article. Review.

73

Isolated absence epilepsy associated with a de novo FBXW7 missense variant in the F-box domain.

Muhammad A, Nosrati MSS, Dostmohammadi A, Madia F, Mancardi MM, Fornarino S, Bosisio L, Tavassol ZH, Omrani MD, Zara F, Scala M. Muhammad A, et al. Epilepsia Open. 2026 Apr;11(2):643-651. doi: 10.1002/epi4.70227. Epub 2026 Feb 13. Epilepsia Open. 2026. PMID: 41685408 Free PMC article.

74

Neuropsychological correlations with fornix and hippocampus in temporal lobe epilepsy demonstrated with diffusion tensor imaging.

Adel SAA, Urlacher J, Beaulieu C, Gross DW. Adel SAA, et al. Epilepsia Open. 2026 Apr;11(2):635-642. doi: 10.1002/epi4.70223. Epub 2026 Feb 12. Epilepsia Open. 2026. PMID: 41678144 Free PMC article.

75

Highly purified cannabidiol (CBD) in CDKL5 deficiency disorder (CDD): Open-label prospective study.

Perulli M, De Gioia A, Ruggiero F, Ascione F, Porto C, Musto E, Massaroni V, Picilli M, Gambardella ML, Quintiliani M, Contaldo I, Veredice C, Battaglia DI. Perulli M, et al. Epilepsia Open. 2026 Apr;11(2):466-474. doi: 10.1002/epi4.70213. Epub 2026 Feb 12. Epilepsia Open. 2026. PMID: 41677102 Free PMC article.

76

Sialidosis type I: How to alleviate disabling myoclonic seizures?-A multicenter analysis of eight cases and review of the literature.

Gburek-Augustat J, Lee IC, Rubino M, Topçu V, Chavez-Castillo M, Tu SC, Shinawi M, Alfradique-Dunham I, Valtcheva M, Adarmes-Gómez A, Macias-Garcia D, Laura Muñoz-Delgado L, Jesús S, Mir P, Merkenschlager A, Coppola A. Gburek-Augustat J, et al. Epilepsia Open. 2026 Apr;11(2):577-591. doi: 10.1002/epi4.70233. Epub 2026 Feb 10. Epilepsia Open. 2026. PMID: 41665440 Free PMC article. Review.

77

Scalp fast oscillations detected by high-density EEG as a noninvasive predictor of surgical outcome in temporal lobe epilepsy with hippocampal sclerosis.

Kongsakorn P, Jirasakuldej S, Treesuthacheep P, Surawattanawong T, Limotai C. Kongsakorn P, et al. Epilepsia Open. 2026 Apr;11(2):564-576. doi: 10.1002/epi4.70232. Epub 2026 Feb 6. Epilepsia Open. 2026. PMID: 41652646 Free PMC article.

78

Stigma, attitude, and knowledge of epilepsy in Italy: A survey on 1159 subjects.

Romozzi M, Tosto F, Turano R, Sbrenna L, Chiffi D, Bianchi F, Trigila V, Vollono C, Assenza G, Tombini M, Calabresi P, Di Tella S, Iannone LF. Romozzi M, et al. Epilepsia Open. 2026 Apr;11(2):527-537. doi: 10.1002/epi4.70225. Epub 2026 Feb 5. Epilepsia Open. 2026. PMID: 41641678 Free PMC article.

79

Cognitive safety under epicranial cortex stimulation of the epileptic focus.

Wagner K, Gorny I, Kustermann J, Losacker JP, Metternich B, Berg J, Sajonz BEA, Coenen VA, Kaufmann E, Knake S, Schulze-Bonhage A. Wagner K, et al. Epilepsia Open. 2026 Apr;11(2):627-634. doi: 10.1002/epi4.70216. Epub 2026 Jan 31. Epilepsia Open. 2026. PMID: 41618965 Free PMC article.

80

Telemedicine in epilepsy care: A Nationwide survey by the Italian Chapter of the International League Against Epilepsy (LICE) on adoption, barriers, and perceived value.

Brigo F, Assenza G, Dono F, Duca M, Lanzone J, Lattanzi S, Licchetta L, Lo Barco T, Spagnoli C, Tassi L, Trivisano M, Mecarelli O. Brigo F, et al. Epilepsia Open. 2026 Apr;11(2):516-526. doi: 10.1002/epi4.70220. Epub 2026 Jan 31. Epilepsia Open. 2026. PMID: 41618811 Free PMC article.

81

Neuropsychological profile and social cognition in children and adolescents with temporal lobe epilepsy.

Accolla C, Preti M, Cappelletto P, De Masi S, Barba C, Guerrini R. Accolla C, et al. Epilepsia Open. 2026 Apr;11(2):504-515. doi: 10.1002/epi4.70224. Epub 2026 Jan 30. Epilepsia Open. 2026. PMID: 41615297 Free PMC article.

82

Fast ripple-delta coupling as an early biomarker for post-traumatic epileptogenesis in repetitive brain injury.

Shandra O, Mahmutovic D, Maharathi B, Arman MA, Benko MJ, Leitzel O, Saha PK, Robel S. Shandra O, et al. Epilepsia Open. 2026 Apr;11(2):409-421. doi: 10.1002/epi4.70211. Epub 2026 Jan 28. Epilepsia Open. 2026. PMID: 41603153 Free PMC article.

83

Semiology in spontaneous versus cortical stimulation-induced seizures during SEEG: A within-patient comparison study.

Mahizhnan M, Dufau S, Phamnguyen J, Kahrom A, Craig D, McGonigal A. Mahizhnan M, et al. Epilepsia Open. 2026 Apr;11(2):488-503. doi: 10.1002/epi4.70221. Epub 2026 Jan 28. Epilepsia Open. 2026. PMID: 41603150 Free PMC article.

84

Clinical outcomes and learning curve of MRgLITT system for drug-resistant epilepsy in China: A single-center retrospective study.

Chen S, Dai Y, Fan X, Wang Y, Wei P, Shan Y, Zhao G. Chen S, et al. Epilepsia Open. 2026 Apr;11(2):475-487. doi: 10.1002/epi4.70218. Epub 2026 Jan 24. Epilepsia Open. 2026. PMID: 41578865 Free PMC article.

85

Sleep enhances gamma oscillations in the seizure onset zone and broadband activity in the irritative zone of focal cortical dysplasia.

Khazali MF, Schwoon N, Brandt A, Dümpelmann M, Li Hegner Y, Roehri N, Altenmüller DM, San Antonio-Arce V, Reinacher PC, Nakagawa JM, Doostkam S, Demerath T, Urbach H, Schulze-Bonhage A, Heers M. Khazali MF, et al. Epilepsia Open. 2026 Apr;11(2):435-451. doi: 10.1002/epi4.70215. Epub 2026 Jan 20. Epilepsia Open. 2026. PMID: 41557258 Free PMC article.

86

Sudden unexpected death in epilepsy (SUDEP): Risk management of pediatric patients with epilepsy.

Lutz L, Becker LL, Koch A, Kaindl AM. Lutz L, et al. Epilepsia Open. 2026 Apr;11(2):422-434. doi: 10.1002/epi4.70214. Epub 2026 Jan 20. Epilepsia Open. 2026. PMID: 41557206 Free PMC article.

87

Abnormal functional connectivity patterns in temporal lobe epilepsy-An international ENIGMA-epilepsy study.

Ives-Deliperi V, Ipser J, Butler JT, Pardoe H, Soltanian-Zadeh H, Rummel C, Wiest R, Keller SS, Kreilkamp BAK, Vaudano AE, Ballerini A, Meletti S, Hall G, Taylor P, Concha L, Fajardo-Valdez A, Casseb RF, Cendes F, Yasuda CL, Lemieux L, Duncan JS, Davoodi-Bodj E, Devinsky O, Thomopoulos SI, Stein DJ, Thompson PM, Sisodiya SM, Gholipour T, McDonald CR. Ives-Deliperi V, et al. Epilepsia Open. 2026 Mar 25. doi: 10.1002/epi4.70209. Online ahead of print. Epilepsia Open. 2026. PMID: 41880651 Free article.

88

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Thompson KW, Suchomelova L, Wasterlain CG. Thompson KW, et al. Epilepsia Open. 2026 Feb 18. doi: 10.1002/epi4.70231. Online ahead of print. Epilepsia Open. 2026. PMID: 41705794 Free article. Review.

89

Predictors of etiology and drug resistance in children with new-onset focal seizures.

Lee BC, Dale RC, Barnes EH, Mohammad SS, Gupta S, Wong C, Gill D, Kothur K. Lee BC, et al. Epilepsia Open. 2026 Feb;11(1):123-135. doi: 10.1002/epi4.70179. Epub 2026 Jan 16. Epilepsia Open. 2026. PMID: 41542891 Free PMC article.

90

Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE.

Tchaicha S, Auvin S, Beniczky S, Brunklaus A, Lagae L, Perucca E, Surges R, Adler S, Helmstaedter C, Jansen F, Rubboli G, Ryvlin P, Specchio N, Trinka E, Blümcke I, de Giorgis V, Kotulska K, Lesca G, Malenica M, McTague A, Nabbout R, Møller RS, Arrieta SS, Brambilla I, Kosla M, Braun K, Cross JH, Arzimanoglou A. Tchaicha S, et al. Epilepsia Open. 2026 Feb;11(1):291-321. doi: 10.1002/epi4.70210. Epub 2026 Jan 5. Epilepsia Open. 2026. PMID: 41489013 Free PMC article.

91

A two-sample Mendelian randomization study and mediation analysis exploring the link between cathepsins and epilepsy.

Sun H, Ma D, Zhang W, Hou S, Chen Z, Li X, Meng H, Zhang D. Sun H, et al. Epilepsia Open. 2026 Feb;11(1):78-88. doi: 10.1002/epi4.70056. Epub 2025 Dec 31. Epilepsia Open. 2026. PMID: 41476372 Free PMC article.

92

Comparison of the effectiveness, safety and tolerability of Perampanel and Levetiracetam as monotherapy in Chinese patients with focal-onset seizures: A single-center, ambispective, open-label, real-world observational study.

Ma H, Zhang R, Zhang Y, Xu H, Qu X, Yang Y, Li J, Yang L, Zhou Q, Zhu H. Ma H, et al. Epilepsia Open. 2026 Feb;11(1):89-100. doi: 10.1002/epi4.70147. Epub 2025 Dec 26. Epilepsia Open. 2026. PMID: 41452106 Free PMC article.

93

The diagnostic value of semiology, EEG and MRI in new-onset pediatric bilateral tonic-clonic seizures: A multimodal analysis.

Moussa B, Nasreddine W, Abboodi H, Beydoun A, Hmeimess G, Wazne J, Shatila AR, Beydoun A. Moussa B, et al. Epilepsia Open. 2026 Feb;11(1):259-269. doi: 10.1002/epi4.70203. Epub 2025 Dec 23. Epilepsia Open. 2026. PMID: 41431867 Free PMC article.

94

Objective outcome assessment in epilepsy surgery using ultralong-term subcutaneous EEG: A case report.

Lisy T, Koren JP, Duarte C, Lang C, Pirker S, Tomschik M, Rössler K, Baumgartner C. Lisy T, et al. Epilepsia Open. 2026 Feb;11(1):340-346. doi: 10.1002/epi4.70205. Epub 2025 Dec 22. Epilepsia Open. 2026. PMID: 41424144 Free PMC article.

95

Clock gene dysregulation in epilepsy: A systematic review.

Fernandes-Campos G, Sen A, Panin F, Sundararaman K. Fernandes-Campos G, et al. Epilepsia Open. 2026 Feb;11(1):53-77. doi: 10.1002/epi4.70206. Epub 2025 Dec 20. Epilepsia Open. 2026. PMID: 41420543 Free PMC article. Review.

96

Distinct medial temporal volumetric signatures in extra-medial temporal lobe lesional epilepsy.

Serlin Y, Patel B, Hayday E, Kilgore-Gomez A, Wu T, Rahman SA, Theodore WH, Inati SK. Serlin Y, et al. Epilepsia Open. 2026 Feb;11(1):230-239. doi: 10.1002/epi4.70201. Epub 2025 Dec 19. Epilepsia Open. 2026. PMID: 41418789 Free PMC article.

97

Effects of vagus nerve stimulation and epilepsy surgery on antiseizure medication usage in pediatric patients with drug-resistant epilepsy in the real world: A retrospective nationwide cohort study.

Lee J, Choi A, Kim S, Eom TH. Lee J, et al. Epilepsia Open. 2026 Feb;11(1):240-249. doi: 10.1002/epi4.70202. Epub 2025 Dec 19. Epilepsia Open. 2026. PMID: 41416994 Free PMC article.

98

A multi-feature method for real-time seizure detection in pediatric intensive care unit.

Sang T, Deng J, Zhao T, Zhang Q, Guan Q, Lei Y, Yan Y, Hong B, Wei N, Jiang Y, Wang Y. Sang T, et al. Epilepsia Open. 2026 Feb;11(1):112-122. doi: 10.1002/epi4.70171. Epub 2025 Dec 19. Epilepsia Open. 2026. PMID: 41416993 Free PMC article.

99

Distinctive genetic architecture of infantile epileptic spasms syndrome compared to self-limited infantile epilepsy by trios whole-exome sequencing.

Sun Y, Chen N, Chen C, Lu W, Wan Q, Li T, Cun Y. Sun Y, et al. Epilepsia Open. 2026 Feb;11(1):280-290. doi: 10.1002/epi4.70208. Epub 2025 Dec 19. Epilepsia Open. 2026. PMID: 41416966 Free PMC article.

100

Incidence and clinical predictors of epilepsy after febrile seizures in children: A prospective cohort study in Vietnam.

Bui AH, Le VKT, Tang HK. Bui AH, et al. Epilepsia Open. 2026 Feb;11(1):270-279. doi: 10.1002/epi4.70207. Epub 2025 Dec 17. Epilepsia Open. 2026. PMID: 41409019 Free PMC article.

101

Cost-effectiveness of fenfluramine as add-on treatment in the management of Dravet Syndrome: A real-world multicenter study.

Cortesi PA, Fornari C, Boncristiano A, Facchetti R, Balestrini S, Doccini V, Specchio N, Pietrafusa N, Trivisano M, Darra F, Cossu A, Battaglia DI, Quintiliani M, Gambardella ML, Mantovani LG, Guerrini R. Cortesi PA, et al. Epilepsia Open. 2026 Feb;11(1):250-258. doi: 10.1002/epi4.70200. Epub 2025 Dec 12. Epilepsia Open. 2026. PMID: 41388477 Free PMC article.

102

Ultra-refractory epilepsy: The newly described entity.

Vinklárek J, Búřilová P, Raouf Zadeh M, Zatloukalová E, Kočvarová J, Strýček O, Pail M, Štillová K, Chrastina J, Brichtová E, Pokorná A, Mazánková D, Brázdil M, Doležalová I. Vinklárek J, et al. Epilepsia Open. 2026 Feb;11(1):220-229. doi: 10.1002/epi4.70196. Epub 2025 Dec 9. Epilepsia Open. 2026. PMID: 41363200 Free PMC article.

103

Prevalence and incidence of infantile epileptic spasms syndrome in India: A systematic review and meta-analysis.

Singh A, Lal P, V S MS, Jain A, Madaan P, Sahu JK, Bansal D. Singh A, et al. Epilepsia Open. 2026 Feb;11(1):211-219. doi: 10.1002/epi4.70197. Epub 2025 Dec 5. Epilepsia Open. 2026. PMID: 41347602 Free PMC article.

104

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug-resistant epilepsy: From operating room to wet lab.

Kyyriäinen J, Della Pietra A, Torkamani-Azar M, Gómez-Budia M, Abushik P, Novosolova N, Eronen H, Narvaez O, Paasonen E, Lezhneva V, Pelkonen A, Saveleva L, Huotarinen A, Belevich I, Jokitalo E; Kuopio Epilepsy Center Epilepsy Surgery Group; Jutila L, Rauramaa T, Immonen A, Leinonen V, Tohka J, Gröhn O, Kälviäinen R, Malm T, Sierra A. Kyyriäinen J, et al. Epilepsia Open. 2026 Feb;11(1):347-362. doi: 10.1002/epi4.70174. Epub 2025 Dec 5. Epilepsia Open. 2026. PMID: 41347599 Free PMC article.

105

Anti-seizure prophylaxis in brain tumors: An Italian survey among epileptologists.

Pasini E, Pauletto G, Maschio M, Michelucci R; Study Group of the Italian League Against Epilepsy (LICE). Pasini E, et al. Epilepsia Open. 2026 Feb;11(1):376-380. doi: 10.1002/epi4.70188. Epub 2025 Dec 4. Epilepsia Open. 2026. PMID: 41340587 Free PMC article. No abstract available.

106

Stiripentol use in Dravet syndrome patients in the USA: Results of a real-world study.

Wirrell E, Wheless J, Perry MS, Laux L, Keough KC, Ziobro J, Luat AF, Aungaroon G, Ciliberto MA, Noel R, Chancharme L, Sullivan J. Wirrell E, et al. Epilepsia Open. 2026 Feb;11(1):200-210. doi: 10.1002/epi4.70191. Epub 2025 Nov 30. Epilepsia Open. 2026. PMID: 41321080 Free PMC article.

107

Late-onset unexplained epilepsy as a risk factor for cognitive impairment and dementia: Protocol for a multi-center prospective longitudinal observational study (ELUCID).

Lam AD, Johnson EL, Sarkis RA, Blank LJ, Gaston TE, Shafi MM, Zepeda R, Pellerin KR, Jette N, Greve DN, Chibnik LB, Amariglio RE, Marshall GA, Westover MB. Lam AD, et al. Epilepsia Open. 2026 Feb;11(1):363-375. doi: 10.1002/epi4.70184. Epub 2025 Nov 29. Epilepsia Open. 2026. PMID: 41317246 Free PMC article.

108

Incidence and prehospital management of convulsive status epilepticus in Martinique, a French Caribbean territory.

Negrello F, Fremery A, Florentin J, Merle S, Aquilina V, Brouste Y, Resiere D, Banydeen R, Gueye P. Negrello F, et al. Epilepsia Open. 2026 Feb;11(1):183-189. doi: 10.1002/epi4.70189. Epub 2025 Nov 22. Epilepsia Open. 2026. PMID: 41273258 Free PMC article.

109

sEEG-guided responsive neurostimulation to treat neocortical epilepsy: A multicenter retrospective study of the efficacy and safety of depth electrode-mediated neuromodulation.

Sadeghzadeh S, Purger DA, Bhanot P, Johnson N, Barbosa DAN, Huang Y, Park JJ, Schonfeld E, Abikenari MA, Jain B, Aronson JP, Drees C, Fisher TL, Gerrard J, Gray TE, Ghatan S, Hines K, Jobst BC, Karakis I, Ojemann SG, Quraishi IH, Raslan AM, Sather MD, Skidmore CT, Willie JT, Wu C, Yoo JY, Graber KD, Halpern CH, Buch VP, Parker JJ. Sadeghzadeh S, et al. Epilepsia Open. 2026 Feb;11(1):146-161. doi: 10.1002/epi4.70180. Epub 2025 Nov 17. Epilepsia Open. 2026. PMID: 41251192 Free PMC article.

110

Neurodevelopmental features in KCNQ2 developmental and epileptic encephalopathy may have limited associations with K_V7.2 dysfunction.

Bidwell JS, Vanoye CG, Desai RR, Berg AT, George AL Jr. Bidwell JS, et al. Epilepsia Open. 2026 Feb;11(1):190-199. doi: 10.1002/epi4.70192. Epub 2025 Nov 18. Epilepsia Open. 2026. PMID: 41250984 Free PMC article.

111

"Epileptic seizure code in the region of Madrid": A process-based healthcare network for the acute management of epileptic seizures.

García Morales I, Serratosa Fernández JM, Rein AG, Koochani NB, Alonso CF, Luján EA, García Ron A, Martínez AM. García Morales I, et al. Epilepsia Open. 2026 Feb;11(1):332-339. doi: 10.1002/epi4.70177. Epub 2025 Nov 18. Epilepsia Open. 2026. PMID: 41250925 Free PMC article.

112

Efficacy and safety of perampanel as first adjunctive therapy in patients with focal-onset seizures or generalized tonic-clonic seizures in four post-marketing studies across regions.

Meletti S, Punia V, Dash A, Gentile AL, Sáinz-Fuertes R, Goldman S, Goldmann T, Patten A, Kumar D, Ngo LY, Steinhoff BJ. Meletti S, et al. Epilepsia Open. 2026 Feb;11(1):101-111. doi: 10.1002/epi4.70183. Epub 2025 Nov 15. Epilepsia Open. 2026. PMID: 41239949 Free PMC article.

113

Cardiovascular morbidity following epilepsy: A nationwide retrospective cohort study in South Korea.

Bae Y, Kang C, Lee Y, Cho H, Jung H, Lee SW. Bae Y, et al. Epilepsia Open. 2026 Feb;11(1):170-182. doi: 10.1002/epi4.70185. Epub 2025 Nov 14. Epilepsia Open. 2026. PMID: 41235461 Free PMC article.

114

Centromedian nucleus targeting in the pediatric population treated with thalamic responsive neurostimulation for drug-resistant epilepsy.

Bercu MM, Zargar BS, Spykman KE, Heredia G, Mogilner AY, Hernandez AW, Patra SE, Burdette DE, Ferrari P. Bercu MM, et al. Epilepsia Open. 2026 Feb;11(1):322-331. doi: 10.1002/epi4.70181. Epub 2025 Nov 13. Epilepsia Open. 2026. PMID: 41231093 Free PMC article.

115

In-hospital outcomes of lacosamide versus levetiracetam for early adjunctive treatment of status epilepticus: A Nationwide Japanese retrospective cohort study.

Nakamura Y, Aso S, Yasunaga H, Matsui H, Shirota Y, Hamada M, Fushimi K, Toda T, Kodama S. Nakamura Y, et al. Epilepsia Open. 2026 Feb;11(1):162-169. doi: 10.1002/epi4.70182. Epub 2025 Nov 12. Epilepsia Open. 2026. PMID: 41222404 Free PMC article.

116

Diagnostic performance of neuroimaging modalities for epileptogenic focus localization: A systematic review.

Alhasan MS, Khalil M, Alhasan AS, Najjar A, Elhassan YH, Almaghraby A, Alharthi O, Hamoud S, Essibayi MA, Feltrin F, Singh S, Milburn J, Azzam AY. Alhasan MS, et al. Epilepsia Open. 2026 Feb;11(1):29-52. doi: 10.1002/epi4.70178. Epub 2025 Nov 10. Epilepsia Open. 2026. PMID: 41215641 Free PMC article. Review.

117

A prospective randomized crossover trial investigating melatonin versus sleep deprivation for sleep induction in nap electroencephalography.

De Giorgis V, Varesio C, Celario M, Quaranta CA, Ferraro F, Pasca L, Fedele G, Papalia G, Palmisani M, Fattore C, Rota P, Franco V. De Giorgis V, et al. Epilepsia Open. 2026 Feb;11(1):136-145. doi: 10.1002/epi4.70169. Epub 2025 Nov 10. Epilepsia Open. 2026. PMID: 41208640 Free PMC article. Clinical Trial.

118

Self-completed patient-reported outcome measures in adults with epilepsy: A review.

Conquest AL, O'Brien TJ, Kwan P, French JA, Malpas CB, Foster EC. Conquest AL, et al. Epilepsia Open. 2026 Feb;11(1):13-28. doi: 10.1002/epi4.70170. Epub 2025 Nov 5. Epilepsia Open. 2026. PMID: 41190498 Free PMC article. Review.

119

Natural language processing-based emotion and usage analysis of an AI-powered chatbot for epilepsy support.

Watanuki K, Oba R, Nozawa N, Ishihara T, Oga K, Iwayama T, Shiganami T, Kobayashi S, Kuga H, Yoshimasu H, Kuramochi I. Watanuki K, et al. Epilepsia Open. 2025 Dec 11. doi: 10.1002/epi4.70186. Online ahead of print. Epilepsia Open. 2025. PMID: 41379632 Free article.

120

Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter-compatible endovascular electroencephalogram electrode: A clinical feasibility trial.

Araki K, Masuda Y, Fujimoto A, Nishimura M, Hosoo H, Ishida H, Enokizono T, Kawai K, Ishikawa E, Matsumaru Y. Araki K, et al. Epilepsia Open. 2025 Dec 6. doi: 10.1002/epi4.70166. Online ahead of print. Epilepsia Open. 2025. PMID: 41351426 Free article.

121

Global, regional and national burden of epilepsy in adolescents aged 10-19 years from 1990 to 2021: An analysis for the Global Burden of Disease Study 2021.

Zhou Z, Chen S, Gao Y, Li G. Zhou Z, et al. Epilepsia Open. 2025 Dec;10(6):1918-1937. doi: 10.1002/epi4.70176. Epub 2025 Oct 31. Epilepsia Open. 2025. PMID: 41171176 Free PMC article.

122

Autoimmune and paraneoplastic encephalitis-associated neuronal autoantibodies with serial EEG in adults with unexplained new-onset seizures or worsening epilepsy.

Cheng CE, Su JJ, Shen C, Lin IT, Chen PY, Jao T. Cheng CE, et al. Epilepsia Open. 2025 Dec;10(6):1978-1989. doi: 10.1002/epi4.70173. Epub 2025 Oct 31. Epilepsia Open. 2025. PMID: 41171170 Free PMC article.

123

Assessing the causal relationship between the plasma proteome and epilepsy: A Mendelian randomization study.

Fu J, Wu W, Shen S. Fu J, et al. Epilepsia Open. 2025 Dec;10(6):1966-1977. doi: 10.1002/epi4.70175. Epub 2025 Oct 30. Epilepsia Open. 2025. PMID: 41165052 Free PMC article.

124

Real-world efficacy and safety of cannabidiol in developmental and epileptic encephalopathies.

Perulli M, Bianchetti M, Pantalone G, Quintiliani M, Gambardella ML, Picilli M, Marini C, Cesaroni E, Battaglia DI. Perulli M, et al. Epilepsia Open. 2025 Dec;10(6):1806-1813. doi: 10.1002/epi4.70149. Epub 2025 Oct 30. Epilepsia Open. 2025. PMID: 41165013 Free PMC article.

125

Hypophosphatemia in suspected seizures evaluated in first seizure clinics and neurology consults.

Binks SNM, Zorkin D, Liem B, Sen A. Binks SNM, et al. Epilepsia Open. 2025 Dec;10(6):2025-2031. doi: 10.1002/epi4.70172. Epub 2025 Oct 27. Epilepsia Open. 2025. PMID: 41144714 Free PMC article.

126

Defining the role of systemic autoimmune markers in adult epilepsy: A focus on autoimmune-associated epilepsy.

Lin IT, Shen C, Chung CT, Cheng CE, Chen PY, Jao T. Lin IT, et al. Epilepsia Open. 2025 Dec;10(6):1905-1917. doi: 10.1002/epi4.70159. Epub 2025 Oct 26. Epilepsia Open. 2025. PMID: 41139404 Free PMC article.

127

Differential glymphatic dysfunction and memory correlation in temporal lobe epilepsy subtypes.

Chen R, Li H, Miao P, Ye H, Chen X, Yang Y, Zhou J, Chen Y, Ge Y, He C, Shao X, Wang Z, Gong Y, Chen C, Wang S, Hu L, Ye L, Ding Y, Wang S, Yang L. Chen R, et al. Epilepsia Open. 2025 Dec;10(6):1953-1965. doi: 10.1002/epi4.70167. Epub 2025 Oct 24. Epilepsia Open. 2025. PMID: 41134131 Free PMC article.

128

Adjunctive acetazolamide for drug-resistant seizures in SLC6A1-related neurodevelopmental disorder: An exploratory case series.

Melikishvili G, Dulac O, Koniashvili O, Mamardashvili G, Gachechiladze T, Tabatadze N, Melikishvili M, Gamirova R, Tomenko T, Bakhtin I, Freed A, Bossi E, Ben-Zeev B, Kluger G, Falace A, Riva A, Kaila K, Striano P. Melikishvili G, et al. Epilepsia Open. 2025 Dec;10(6):2009-2017. doi: 10.1002/epi4.70155. Epub 2025 Oct 23. Epilepsia Open. 2025. PMID: 41131961 Free PMC article.

129

Reply to Letter to the Editor regarding the article "SCN1A gain of function effects in Dravet syndrome: Insights into clinical phenotypes and therapeutic implications".

Kobayashi Takahashi Y, Tabata K, Baba S, Takeshita E, Sumitomo N, Shimizu-Motohashi Y, Saito T, Nakagawa E, Ishii A, Hirose S, Kato M, Matsumoto N, Komaki H, Inoue K. Kobayashi Takahashi Y, et al. Epilepsia Open. 2025 Dec;10(6):2036-2038. doi: 10.1002/epi4.70153. Epub 2025 Oct 23. Epilepsia Open. 2025. PMID: 41128814 Free PMC article. No abstract available.

130

To the editors: SCN1A gain-of-function effects in Dravet syndrome: Insights into clinical phenotypes and therapeutic implications.

Müller-Wöhrstein P, Lerche H, Boßelmann CM. Müller-Wöhrstein P, et al. Epilepsia Open. 2025 Dec;10(6):2032-2035. doi: 10.1002/epi4.70154. Epub 2025 Oct 23. Epilepsia Open. 2025. PMID: 41128783 Free PMC article. No abstract available.

131

A systematic survey of the measures used to identify postoperative changes in language function following epilepsy surgery.

Puntambekar I, Koepp M, Xiao F, Baxendale S. Puntambekar I, et al. Epilepsia Open. 2025 Dec;10(6):1751-1761. doi: 10.1002/epi4.70164. Epub 2025 Oct 21. Epilepsia Open. 2025. PMID: 41118271 Free PMC article.

132

Using stereo-electroencephalography data to model the optimal intracranial venous sinus location for an endovascular seizure detection device: A feasibility study.

Wittayacharoenpong T, Rind G, Hunn M, Gutman M, Hudson M, Chen Z, Laing J, O'Brien TJ, Opie N, Neal A. Wittayacharoenpong T, et al. Epilepsia Open. 2025 Dec;10(6):1938-1952. doi: 10.1002/epi4.70163. Epub 2025 Oct 17. Epilepsia Open. 2025. PMID: 41105453 Free PMC article.

133

Green epileptology: Acceptance of telemedical follow-up under climate protection aspects.

Kilburg RL, Moskau-Hartmann S, Helmstaedter C, Surges R, von Wrede R. Kilburg RL, et al. Epilepsia Open. 2025 Dec;10(6):1883-1891. doi: 10.1002/epi4.70162. Epub 2025 Oct 14. Epilepsia Open. 2025. PMID: 41085293 Free PMC article.

134

Progressive clonic slowing predicts severity of respiratory dysfunction and prolonged postictal immobility in tonic-clonic seizures.

Phamnguyen J, Tremayne F, Vadlamudi L, Lander C, Walsh S, Chen X, Sullivan AA, Vegh V, Reutens D. Phamnguyen J, et al. Epilepsia Open. 2025 Dec;10(6):1892-1904. doi: 10.1002/epi4.70161. Epub 2025 Oct 14. Epilepsia Open. 2025. PMID: 41085214 Free PMC article.

135

Seizures beget more than seizures: Understanding the cellular, structural, individual and societal impact of seizures in epilepsy.

Walker MC, Galovic M, Álvarez-Barón E, Strzelczyk A. Walker MC, et al. Epilepsia Open. 2025 Dec;10(6):1762-1773. doi: 10.1002/epi4.70143. Epub 2025 Oct 10. Epilepsia Open. 2025. PMID: 41071564 Free PMC article. Review.

136

Driving after vagus nerve stimulation therapy: Is it possible?

Peña-Ceballos J, Choekyi T, Colleran N, Staunton-Grufferty B, Dempsey N, Lewis-Smith D, El Naggar H, Sweeney KJ, O'Brien D, Moloney PB, Delanty N. Peña-Ceballos J, et al. Epilepsia Open. 2025 Dec;10(6):2018-2024. doi: 10.1002/epi4.70160. Epub 2025 Oct 10. Epilepsia Open. 2025. PMID: 41071543 Free PMC article.

137

Using Cenobamate for managing idiopathic generalized epilepsy: A single-center experience and systematic literature review.

Woodrich N, Alexopoulos A, Nair D, Najm IM, Punia V. Woodrich N, et al. Epilepsia Open. 2025 Dec;10(6):1871-1882. doi: 10.1002/epi4.70157. Epub 2025 Oct 7. Epilepsia Open. 2025. PMID: 41056140 Free PMC article.

138

Simultaneous tDCS-rTMS stimulation to regulate the language network and improve language ability in Landau-Kleffner syndrome.

Chen R, Liu X, Qi X, Shen W, Leng X, Zhang X, Zhang L, Zhang Y, Zhao X, Wang X, Zhang J, Wang Y, Lin Y. Chen R, et al. Epilepsia Open. 2025 Dec;10(6):1997-2008. doi: 10.1002/epi4.70114. Epub 2025 Oct 6. Epilepsia Open. 2025. PMID: 41051942 Free PMC article.

139

Rescue epilepsy medication and training: A comparison between midazolam use, guidelines, clinical practice, and possibilities in the UK and Norway.

McBride A, Henning OJ, Johannessen Landmark C, Watkins L, Tromans S, Basset P, Triantafyllopoulou P, Shankar R. McBride A, et al. Epilepsia Open. 2025 Dec;10(6):1824-1834. doi: 10.1002/epi4.70145. Epub 2025 Oct 6. Epilepsia Open. 2025. PMID: 41051929 Free PMC article.

140

Late-onset epilepsy of unknown etiology is more treatment-responsive than acquired lesional late-onset epilepsy.

Hickman LB, Pandey B, Fish A, Bandla M, Husein A, Allas C, Kottakota H, Herzog L, Vossel K, Stern JM. Hickman LB, et al. Epilepsia Open. 2025 Dec;10(6):1847-1859. doi: 10.1002/epi4.70156. Epub 2025 Oct 6. Epilepsia Open. 2025. PMID: 41051912 Free PMC article.

141

Carotid intima-media thickness may be an early biomarker for cardiovascular risk in patients treated with ketogenic dietary therapy.

Haavardsholm KC, Zamani M, Skjelland M, Ramm-Pettersen A, Skagen K. Haavardsholm KC, et al. Epilepsia Open. 2025 Dec;10(6):1860-1870. doi: 10.1002/epi4.70152. Epub 2025 Sep 30. Epilepsia Open. 2025. PMID: 41026111 Free PMC article.

142

The challenge of ultra-rarity: Dual diagnosis of Lafora disease and developmental encephalopathies linked to TRIO and SHANK3 pathogenic variants.

Muccioli L, Bisulli F, Minardi R, Valentino ML, De Simone M, Paroni RA, Cesnik E, Fallica E, Bonan L, Pizzi E; DEFEAT‐LD Study Group; Cantalupo G, Licchetta L. Muccioli L, et al. Epilepsia Open. 2025 Dec;10(6):1990-1996. doi: 10.1002/epi4.70104. Epub 2025 Sep 26. Epilepsia Open. 2025. PMID: 41003650 Free PMC article.

143

Nonseizure symptoms and broader seizure impacts in patients with Dravet syndrome and Lennox-Gastaut syndrome in clinical practice settings: Results from a multinational survey.

Shah D, Villanueva V, Dlugos D, Benitez A, Taylor Y, Olsen S, Connolly H, Lai S, Andrews JS. Shah D, et al. Epilepsia Open. 2025 Dec;10(6):1783-1797. doi: 10.1002/epi4.70118. Epub 2025 Sep 22. Epilepsia Open. 2025. PMID: 40982357 Free PMC article.

144

Unmet needs of women with epilepsy living in rural low- and middle-income countries: The experience of the Bolivian Chaco.

Nicoletti A, Latino G, Cicero CE, Barbiero A, Aguzzoli C, Ribelli B, Petrini V, Micieli M, Padilla S, Vilte E, Cosmi F, Crespo Gomez EB, Bartoloni A, Giuliano L. Nicoletti A, et al. Epilepsia Open. 2025 Dec;10(6):1774-1782. doi: 10.1002/epi4.13125. Epub 2025 Sep 22. Epilepsia Open. 2025. PMID: 40982356 Free PMC article.

145

The effect of cortical and subcortical parcel volumes on postictal generalized EEG suppression.

Bascarevic V, Jokovic Z, Hadziosmanovic S, Pejovic A, Koepp M, Xiao F, Binding L, Bukumiric Z, Vojvodic N, Sokic D, Ristic AJ. Bascarevic V, et al. Epilepsia Open. 2025 Dec;10(6):1798-1805. doi: 10.1002/epi4.70150. Epub 2025 Sep 20. Epilepsia Open. 2025. PMID: 40974544 Free PMC article.

146

Current practices and trends in surgical decision-making for children with Lennox-Gastaut syndrome: A cross-sectional survey by the Pediatric Epilepsy Research Consortium.

Chiu MY, Keator CG, Warren AEL, Knowles JK, Samanta D, Dixon-Salazar T, Koh HY, Seinfeld SA, Paolicchi J, Vidaurre J, Patel AD, Loddenkemper T, Shellhaas RA, Clarke DF, Fine AL, Bhalla S, Depositario-Cabacar D, Haridas B, Stafstrom CE, Erdemir G, Karakas C. Chiu MY, et al. Epilepsia Open. 2025 Dec;10(6):1835-1846. doi: 10.1002/epi4.70144. Epub 2025 Sep 18. Epilepsia Open. 2025. PMID: 40965114 Free PMC article.

147

Beliefs, misconceptions, and practices related to epilepsy among adults in Sudan: A large-scale cross-sectional study.

Ahmed MBM, Hussein IAM, Ahmed ABM, Alhaj EAA, Hussein SAA, Omer DHA, Ali HAS, Mohamed AHA, Salih MAM, Ahmed HAH, Ibrahim DEAEA, Ahmed SMM. Ahmed MBM, et al. Epilepsia Open. 2025 Dec;10(6):1814-1823. doi: 10.1002/epi4.70148. Epub 2025 Sep 16. Epilepsia Open. 2025. PMID: 40956593 Free PMC article.

148

How to report neurotechnology and artificial intelligence studies in epilepsy: Peer-review-inspired recommendations.

Viana PF, McWilliam M, Biondi A, Medel-Matus JS, Kuroda N, Cereda GS, Galanopoulou AS. Viana PF, et al. Epilepsia Open. 2025 Nov 27. doi: 10.1002/epi4.70194. Online ahead of print. Epilepsia Open. 2025. PMID: 41311101 Free article.

149

ENCEVIS: Evaluating the feasibility of an AI-based algorithm as an assistant to neurophysiologists in clinical practice.

Tsereteli A, Okujava N, Malashkhia N, Sakvarelidze T. Tsereteli A, et al. Epilepsia Open. 2025 Nov 19. doi: 10.1002/epi4.70193. Online ahead of print. Epilepsia Open. 2025. PMID: 41258654 Free article.

150

Epilepsy surgery: From bench to the clinics.

Tanaka T. Tanaka T. Epilepsia Open. 2025 Nov 17. doi: 10.1002/epi4.70190. Online ahead of print. Epilepsia Open. 2025. PMID: 41251188 Free article.

151

Ketogenic diet for infantile epileptic spasms.

Scantlebury MH, Choudhary A, Ng AC, Gavrilovici C. Scantlebury MH, et al. Epilepsia Open. 2025 Oct 29. doi: 10.1002/epi4.70168. Online ahead of print. Epilepsia Open. 2025. PMID: 41159707 Free article.

152

The multiple hit model of infantile and epileptic spasms: The 2025 update.

Galanopoulou AS, Mowrey WB, Liu W, Katsarou AM, Li Q, Shandra O, Moshé SL. Galanopoulou AS, et al. Epilepsia Open. 2025 Oct 14. doi: 10.1002/epi4.70158. Online ahead of print. Epilepsia Open. 2025. PMID: 41085349 Free article.

153

Characterizing the burden of healthcare utilization and expenditure for epilepsy and unclassified seizures in the U.S., 2016-2022.

Rajadhyaksha PM, Suh K. Rajadhyaksha PM, et al. Epilepsia Open. 2025 Oct;10(5):1648-1659. doi: 10.1002/epi4.70135. Epub 2025 Sep 15. Epilepsia Open. 2025. PMID: 40952381 Free PMC article.

154

MonoPER study: Effectiveness and tolerability of PERampanel in monotherapy in real-world after 12 months of treatment.

Fernández-Cabrera A, Santamaría-Montero P, García de-Soto J, Pego-Reigosa R. Fernández-Cabrera A, et al. Epilepsia Open. 2025 Oct;10(5):1587-1594. doi: 10.1002/epi4.70122. Epub 2025 Sep 14. Epilepsia Open. 2025. PMID: 40947856 Free PMC article.

155

A cross-national cost-effectiveness analysis of brivaracetam focusing on psychiatric and behavioral adverse effects.

Maruyama Y, Kimura H, Nishida T, Ogawa S, Ninomiya K, Ikeda M. Maruyama Y, et al. Epilepsia Open. 2025 Oct;10(5):1684-1694. doi: 10.1002/epi4.70142. Epub 2025 Sep 13. Epilepsia Open. 2025. PMID: 40944872 Free PMC article.

156

Prospective evaluation of clinical characteristics, treatment efficacy, and seizure remission in adult-onset genetic generalized epilepsy.

Khalife L, Harb A, Jaafar F, Beydoun A, Wazne J, Toufaili H, Moussa B, Beydoun A. Khalife L, et al. Epilepsia Open. 2025 Oct;10(5):1673-1683. doi: 10.1002/epi4.70141. Epub 2025 Sep 13. Epilepsia Open. 2025. PMID: 40944700 Free PMC article.

157

Long-term plasma monitoring of THC and CBD in pediatric drug-resistant epilepsy: Implications for cannabidiol therapy with Epidyolex®.

Cafaro A, Riva A, Pigliasco F, Barco S, Manca V, Stella Vari M, Mancardi MM, Nobili L, Pichini S, Busardò FP, Striano P, Cangemi G. Cafaro A, et al. Epilepsia Open. 2025 Oct;10(5):1699-1704. doi: 10.1002/epi4.70112. Epub 2025 Sep 12. Epilepsia Open. 2025. PMID: 40938500 Free PMC article.

158

Potential of ⁴He OPM-MEG for detecting interictal epileptic activity: A comparison with SQUID-MEG.

Schwartz D, Badier JM, Gutteling TP, Daligault S, Labyt E, Bonini F, Jung J. Schwartz D, et al. Epilepsia Open. 2025 Oct;10(5):1660-1672. doi: 10.1002/epi4.70139. Epub 2025 Sep 12. Epilepsia Open. 2025. PMID: 40937825 Free PMC article.

159

Clinical utility of an ambulatory absence seizure detection system.

Zabler N, Biondi A, Kalousios S, Novitskaya Y, Faber H, Dümpelmann M, Schulze-Bonhage A, Hirsch M. Zabler N, et al. Epilepsia Open. 2025 Oct;10(5):1733-1739. doi: 10.1002/epi4.70138. Epub 2025 Sep 11. Epilepsia Open. 2025. PMID: 40932588 Free PMC article.

160

Etiological diagnosis of late-onset epilepsy: A key priority for Italian epileptologists - Insights from a LICE survey.

Nardi Cesarini E, Falcicchio G, Librizzi L, Sciaccaluga M, Assenza G, Galimberti CA, Giorgi FS, DiFrancesco JC, Costa C; “Late‐Onset Epilepsy Study Group” of the Lega Italiana contro l'Epilessia (LICE), the Italian Chapter of the International League Against Epilepsy (ILAE). Nardi Cesarini E, et al. Epilepsia Open. 2025 Oct;10(5):1639-1647. doi: 10.1002/epi4.70131. Epub 2025 Sep 11. Epilepsia Open. 2025. PMID: 40931963 Free PMC article.

161

Neurologists' perspectives on SUDEP communication: A comparative study across five European countries.

Moon S, Watkins L, Zelano J, Villanueva V, Ravichandra N, Jordán Z, Kelemen A, Bassett P, Henning OJ, Tomson T, Shankar R. Moon S, et al. Epilepsia Open. 2025 Oct;10(5):1545-1557. doi: 10.1002/epi4.70129. Epub 2025 Sep 1. Epilepsia Open. 2025. PMID: 40888281 Free PMC article.

162

Effectiveness and safety of early add-on therapy with brivaracetam in patients with poorly controlled focal seizures in routine clinical practice: BRIV-add study.

Serrano-Castro PJ, Caballero-Martínez F, Campos-Lucas FJ, Campos-Fernández D, de Aguilar-Amat MJ, García A, Gifreu A, Santamaría-Rodríguez I, Poza JJ, Toledo-Argany M; Grupo de Investigadores Colaboradores. Serrano-Castro PJ, et al. Epilepsia Open. 2025 Oct;10(5):1334-1344. doi: 10.1002/epi4.70073. Epub 2025 Aug 30. Epilepsia Open. 2025. PMID: 40884534 Free PMC article.

163

The role of neuropsychology in stereo-EEG: A narrative review.

Cockle E, Malpas CB, Alpitsis R, O'Brien TJ, Rayner G, Neal A. Cockle E, et al. Epilepsia Open. 2025 Oct;10(5):1284-1299. doi: 10.1002/epi4.70124. Epub 2025 Aug 30. Epilepsia Open. 2025. PMID: 40884528 Free PMC article. Review.

164

Long-term outcomes of a cohort of patients with pharmacoresistant neonatal epilepsy and negative brain MRI.

Beretti T, Rozalen W, Villard L, Riccardi F, Daquin G, Lepine A, Villeneuve N, Milh M, Desnous B. Beretti T, et al. Epilepsia Open. 2025 Oct;10(5):1605-1616. doi: 10.1002/epi4.70126. Epub 2025 Aug 30. Epilepsia Open. 2025. PMID: 40884527 Free PMC article.

165

Barriers to the implementation of epilepsy genetic testing and counseling guidelines.

Melly S, Bergner AL, Sands T, Lippa N, Mulhern M. Melly S, et al. Epilepsia Open. 2025 Oct;10(5):1595-1604. doi: 10.1002/epi4.70125. Epub 2025 Aug 29. Epilepsia Open. 2025. PMID: 40879149 Free PMC article.

166

Attitude of people with epilepsy in Serbia toward surgical treatment of epilepsy.

Mihailović I, Pejović A, Ilić A, Milovanović M, Jagodić V, Sakač S, Jovanović G, Biševac B, Asadi-Pooya AA, Vojvodić N, Sokić D, Ristić AJ. Mihailović I, et al. Epilepsia Open. 2025 Oct;10(5):1353-1360. doi: 10.1002/epi4.70081. Epub 2025 Aug 28. Epilepsia Open. 2025. PMID: 40875518 Free PMC article.

167

Deficiency of nNOS in adult-born dentate granule cells causes epilepsy.

Huang H, Yang Y, Wang J, Mao Z, Zhou Z, Zeng Y, Xu H, Zhou Y, Song X, You Y, Zhou Q, Meng F. Huang H, et al. Epilepsia Open. 2025 Oct;10(5):1617-1629. doi: 10.1002/epi4.70133. Epub 2025 Aug 28. Epilepsia Open. 2025. PMID: 40874679 Free PMC article.

168

Investigating the frequency of unreported cases and laboratory correspondence practices for variants of uncertain significance in pediatric epilepsy.

Vilaboy T, Wong K, Tristani-Firouzi M, Sandoval Karamian AG, Palmquist R. Vilaboy T, et al. Epilepsia Open. 2025 Oct;10(5):1726-1732. doi: 10.1002/epi4.70132. Epub 2025 Aug 26. Epilepsia Open. 2025. PMID: 40857170 Free PMC article.

169

Parent perceptions of their child's cognitive impairment linked to their views on support for healthcare transition.

Clark SJ, Cowan AE, Raja S, DeVries S. Clark SJ, et al. Epilepsia Open. 2025 Oct;10(5):1719-1725. doi: 10.1002/epi4.70127. Epub 2025 Aug 23. Epilepsia Open. 2025. PMID: 40847800 Free PMC article.

170

Why patients say no: Patient barriers to epilepsy surgery among patients with drug-resistant epilepsy in Singapore.

Tan Z, Shanmugham M, Adiyapatham S, Chan ZE, Chan ZY, Ling HC, Shen JY, Gosavi T, De Silva DA, Lim SH. Tan Z, et al. Epilepsia Open. 2025 Oct;10(5):1630-1638. doi: 10.1002/epi4.70128. Epub 2025 Aug 22. Epilepsia Open. 2025. PMID: 40844479 Free PMC article.

171

Effectiveness of perampanel as the only adjunctive anti-seizure medication in adults: Final results from the observational PERPRISE study in Germany.

Steinhoff BJ, Goldmann T, Kockelmann E, Winter Y. Steinhoff BJ, et al. Epilepsia Open. 2025 Oct;10(5):1489-1504. doi: 10.1002/epi4.70117. Epub 2025 Aug 21. Epilepsia Open. 2025. PMID: 40839459 Free PMC article.

172

Support vector machines predict postoperative memory outcomes in temporal lobe epilepsies.

Ethofer S, Erb M, Milian M, Rona S, Lerche H, Honegger J, Ethofer T. Ethofer S, et al. Epilepsia Open. 2025 Oct;10(5):1558-1574. doi: 10.1002/epi4.70119. Epub 2025 Aug 20. Epilepsia Open. 2025. PMID: 40834432 Free PMC article.

173

Predictive value of traditional laboratory parameters and inflammatory indices for same-day seizure recurrence in patients with epileptic seizures.

Alemdar M, Sarıca Darol E, Polat AK. Alemdar M, et al. Epilepsia Open. 2025 Oct;10(5):1575-1586. doi: 10.1002/epi4.70123. Epub 2025 Aug 18. Epilepsia Open. 2025. PMID: 40824701 Free PMC article.

174

Exploring transition in epilepsy within ERN EpiCARE centers: Insights from a survey analysis.

De Giorgis V, Malenica M, Pasca L, Bibic I, Bibic V, Bisulli F, Darra F, Granata T, Ragona F, Rubboli G, Harrington BT, Brambilla I, Nabbout R. De Giorgis V, et al. Epilepsia Open. 2025 Oct;10(5):1705-1718. doi: 10.1002/epi4.70121. Epub 2025 Aug 18. Epilepsia Open. 2025. PMID: 40824185 Free PMC article.

175

Epilepsy and systemic autoimmune diseases: A bidirectional two-sample Mendelian randomization study.

Tian R, Yu W, Hu J, Yang Y, He X. Tian R, et al. Epilepsia Open. 2025 Oct;10(5):1415-1425. doi: 10.1002/epi4.70102. Epub 2025 Aug 17. Epilepsia Open. 2025. PMID: 40819367 Free PMC article.

176

A model-based cost-effectiveness estimates of hormonal therapy in Indian children with infantile epileptic spasms syndrome.

Devi N, Madaan P, Bharti SK, Sahu JK, Bansal D. Devi N, et al. Epilepsia Open. 2025 Oct;10(5):1404-1414. doi: 10.1002/epi4.70106. Epub 2025 Aug 12. Epilepsia Open. 2025. PMID: 40794098 Free PMC article.

177

A companion to the development of common data elements for Sudden Unexpected Death in Epilepsy (SUDEP).

Iyengar SS, O'Loughlin EK, Harte-Hargrove L, Holmay M, Lubbers LS; CURE Epilepsy SUDEP Data Standardization Project Steering Committee; Working Group Members. Iyengar SS, et al. Epilepsia Open. 2025 Oct;10(5):1439-1449. doi: 10.1002/epi4.70103. Epub 2025 Aug 9. Epilepsia Open. 2025. PMID: 40782095 Free PMC article.

178

Exploring the long-term effects of COVID-19 in patients with epilepsy: A multicenter Italian observational study.

Dono F, Russo M, Evangelista G, Corniello C, Liguori C, Calvello C, Narducci F, Vollono C, Sensi S. Dono F, et al. Epilepsia Open. 2025 Oct;10(5):1450-1461. doi: 10.1002/epi4.70108. Epub 2025 Aug 9. Epilepsia Open. 2025. PMID: 40782040 Free PMC article.

179

General mental ability (Spearman's g) in Juvenile Myoclonic Epilepsy.

Struck AF, Garcia-Ramos C, Prabhakaran V, Nair V, Adluru A, Almane D, Adluru N, Jones JE, Hermann BP. Struck AF, et al. Epilepsia Open. 2025 Oct;10(5):1519-1531. doi: 10.1002/epi4.70111. Epub 2025 Aug 8. Epilepsia Open. 2025. PMID: 40778661 Free PMC article.

180

Enhanced response inhibition in patients with drug-resistant juvenile myoclonic epilepsy: Event-related potentials evidence of excitatory-inhibitory imbalance.

Sarah L, Yam M, Goldstein L, Fahoum F, Noam BE, Maidan I. Sarah L, et al. Epilepsia Open. 2025 Oct;10(5):1532-1544. doi: 10.1002/epi4.70115. Epub 2025 Aug 7. Epilepsia Open. 2025. PMID: 40773354 Free PMC article.

181

Gingival enlargement following levetiracetam treatment: A clinical case analysis.

Alahmari AM, Alkhathaami AM. Alahmari AM, et al. Epilepsia Open. 2025 Oct;10(5):1695-1698. doi: 10.1002/epi4.70051. Epub 2025 Aug 6. Epilepsia Open. 2025. PMID: 40768742 Free PMC article.

182

What determines the timing of epilepsy surgery in children with cortical malformations and low-grade epilepsy-associated tumors?

Sanders MWCB, Ebel M, Chari A, Fleumer M, Vasilica AM, Eriksson MH, Tisdall M, Splitkova B, Belohlavkova A, Otte WM, Jansen FE, Cross JH, Braun KPJ, Krsek P. Sanders MWCB, et al. Epilepsia Open. 2025 Oct;10(5):1345-1352. doi: 10.1002/epi4.70074. Epub 2025 Aug 6. Epilepsia Open. 2025. PMID: 40767023 Free PMC article.

183

Enhancing sudden unexpected death in epilepsy (SUDEP) research through development of common data elements.

Iyengar SS, O'Loughlin EK, Harte-Hargrove L, Holmay M, Lubbers LS; CURE Epilepsy SUDEP Data Standardization Project Steering Committee; CURE Epilepsy SUDEP Data Standardization Project Working Group Members. Iyengar SS, et al. Epilepsia Open. 2025 Oct;10(5):1426-1438. doi: 10.1002/epi4.70105. Epub 2025 Aug 4. Epilepsia Open. 2025. PMID: 40758441 Free PMC article.

184

Facilitators and barriers of antiseizure medication adherence from Australian healthcare providers' perspectives: A qualitative study.

Conquest A, Sharma S, Lawn N, Todd L, Wait L, Friderichs M, Kwan P, Reeder S, Foster E. Conquest A, et al. Epilepsia Open. 2025 Oct;10(5):1475-1488. doi: 10.1002/epi4.70110. Epub 2025 Jul 30. Epilepsia Open. 2025. PMID: 40736360 Free PMC article.

185

Abnormalities of thalamus and thalamocortical pathways in patients with refractory epilepsy caused by focal cortical dysplasia - MRI study.

Kala D, Prysiazhniuk Y, Michal L, Šanda J, Holubová Z, Kudr M, Krýsl D, Maulisová A, Jiránková K, Marusič P, Kršek P, Kynčl M, Otáhal J. Kala D, et al. Epilepsia Open. 2025 Oct;10(5):1505-1518. doi: 10.1002/epi4.70109. Epub 2025 Jul 28. Epilepsia Open. 2025. PMID: 40720244 Free PMC article.

186

Redefining drug-resistant epilepsy: Insights from an Italian Delphi consensus study.

Vigevano F, Bagnasco I, Di Gennaro G, Mecarelli O, Lattanzi S. Vigevano F, et al. Epilepsia Open. 2025 Oct;10(5):1311-1322. doi: 10.1002/epi4.70085. Epub 2025 Jul 25. Epilepsia Open. 2025. PMID: 40709544 Free PMC article.

187

Transition to Adult Care in Childhood-Onset Epilepsy: A Retrospective Cohort Study at a Japanese Children's Hospital.

Aihara T, Abe Y, Hayakawa I. Aihara T, et al. Epilepsia Open. 2025 Oct;10(5):1388-1395. doi: 10.1002/epi4.70092. Epub 2025 Jul 21. Epilepsia Open. 2025. PMID: 40686089 Free PMC article.

188

Altered along-the-perivascular space index in functional (psychogenic non-epileptic) seizures: A diffusion tensor imaging study of glymphatic system function.

Roozbeh M, Mirbagheri MM, Arbabi M, Asadi-Pooya AA, Khodagholi F, Amiri S. Roozbeh M, et al. Epilepsia Open. 2025 Oct;10(5):1361-1372. doi: 10.1002/epi4.70089. Epub 2025 Jul 19. Epilepsia Open. 2025. PMID: 40682763 Free PMC article.

189

Bradycardia is induced by hyperactivity of the vagus nerve and nucleus ambiguus during seizures propagating into the brainstem.

Chiang CC, Kotamraju BP, Durand DM. Chiang CC, et al. Epilepsia Open. 2025 Oct;10(5):1300-1310. doi: 10.1002/epi4.70060. Epub 2025 Jul 18. Epilepsia Open. 2025. PMID: 40680751 Free PMC article.

190

Cognitive outcomes after deep brain stimulation in drug-resistant epilepsy: A comparison of anterior thalamic and hippocampal stimulation.

Kim S, Jung S, Lee S, Joo EY, Seo DW, Shon YM. Kim S, et al. Epilepsia Open. 2025 Oct;10(5):1462-1474. doi: 10.1002/epi4.70107. Epub 2025 Jul 18. Epilepsia Open. 2025. PMID: 40679272 Free PMC article.

191

Efficacy and tolerability of fenfluramine with concomitant potassium bromide in patients with Dravet syndrome.

Pringsheim M, Kluger G, Strzelczyk A, Schubert-Bast S, Mayer T, Glauche B, Muhle H, Alber M, Spors H, Polster T, Trollmann R, Kurlemann G, Berndt M, Klotz KA. Pringsheim M, et al. Epilepsia Open. 2025 Oct;10(5):1323-1333. doi: 10.1002/epi4.70079. Epub 2025 Jul 17. Epilepsia Open. 2025. PMID: 40673648 Free PMC article.

192

Neuronal surface and intracellular antibody testing in patients with long-term epilepsy.

Watanabe N, Lizcano A, de Araujo TK, Barbosa R, Alvim MKM, Vieira AS, Lopes-Cendes I, Rogerio F, Yasuda CL, Cendes F. Watanabe N, et al. Epilepsia Open. 2025 Oct;10(5):1373-1387. doi: 10.1002/epi4.70096. Epub 2025 Jul 15. Epilepsia Open. 2025. PMID: 40662319 Free PMC article.

193

Ictal emotional features in pediatric and young adult patients with frontal lobe epilepsy.

Tsai MC, Lin CP, Fine A, Nickels K, Starnes K, Wirrell E, Wong-Kisiel LC. Tsai MC, et al. Epilepsia Open. 2025 Oct;10(5):1396-1403. doi: 10.1002/epi4.70097. Epub 2025 Jul 12. Epilepsia Open. 2025. PMID: 40650864 Free PMC article.

194

Prenatal betamethasone-postnatal N-methyl-D-aspartic acid model of spasms: Update on mechanisms and treatments.

Vieira K, Schonwald A, Chern CR, Shah K, Velíšková J, Velíšek L. Vieira K, et al. Epilepsia Open. 2025 Sep 16. doi: 10.1002/epi4.70140. Online ahead of print. Epilepsia Open. 2025. PMID: 40956119 Free article.

195

Status epilepticus: Updates on mechanisms and treatments.

Joshi S, Kapur J. Joshi S, et al. Epilepsia Open. 2025 Sep 16. doi: 10.1002/epi4.70146. Online ahead of print. Epilepsia Open. 2025. PMID: 40956087 Free article. Review.

196

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges.

Medel-Matus JS, Santana-Gomez C, Escalante RG, Duncan D, Viana PF, Cereda GS, Kuroda N, Galanopoulou AS. Medel-Matus JS, et al. Epilepsia Open. 2025 Sep 12. doi: 10.1002/epi4.70137. Online ahead of print. Epilepsia Open. 2025. PMID: 40938346 Free article. Review.

197

Epileptic drop attacks: More than just atonic seizures.

Ono T, Sato K, Honda R, Otsubo H. Ono T, et al. Epilepsia Open. 2025 Sep 12. doi: 10.1002/epi4.70136. Online ahead of print. Epilepsia Open. 2025. PMID: 40937826 Free article.

198

AI-based localization of the epileptogenic zone using intracranial EEG.

Daida A, Zhang Y, Kanai S, Staba R, Roychowdhury V, Nariai H. Daida A, et al. Epilepsia Open. 2025 Aug 25. doi: 10.1002/epi4.70130. Online ahead of print. Epilepsia Open. 2025. PMID: 40853284 Free article. Review.

199

Febrile status epilepticus and epileptogenesis: The FEBSTAT study.

Lewis DV, Nordli DR Jr, Nordli DR 3rd, Shinnar S, Chan S, Bello JA, Frank LM, Voyvodic J, Gallentine W, Seinfeld S, Sogawa Y, Weiss E, Masur D, Xu Y, Moshé SL. Lewis DV, et al. Epilepsia Open. 2025 Aug 6. doi: 10.1002/epi4.70113. Online ahead of print. Epilepsia Open. 2025. PMID: 40770931 Free article.

200

Frontiers in EEG as a tool for the management of pediatric epilepsy: Past, present, and future.

Nariai H. Nariai H. Epilepsia Open. 2025 Aug 4. doi: 10.1002/epi4.70116. Online ahead of print. Epilepsia Open. 2025. PMID: 40758428 Free article.

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