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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
1965 2
1966 8
1967 5
1968 7
1969 6
1970 6
1971 8
1972 7
1973 5
1974 15
1975 30
1976 33
1977 35
1978 45
1979 51
1980 51
1981 64
1982 76
1983 72
1984 121
1985 126
1986 128
1987 137
1988 161
1989 175
1990 216
1991 240
1992 233
1993 272
1994 251
1995 262
1996 262
1997 423
1998 652
1999 661
2000 802
2001 938
2002 976
2003 1155
2004 1346
2005 1587
2006 1904
2007 2306
2008 2345
2009 2619
2010 3026
2011 3127
2012 3167
2013 3315
2014 3347
2015 3366
2016 3243
2017 3322
2018 3583
2019 1414
2020 24
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46,056 results
Results by year
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Page 1
Chronic Liver Injury Induces Conversion of Biliary Epithelial Cells into Hepatocytes.
Deng X, et al. Cell Stem Cell 2018. PMID 29937200 Free article.
In this study, we modeled human chronic liver injuries, in which such responses are blunted, without genetic manipulations, and assessed potential contributions of non-parenchymal cells (NPCs) to hepatocyte regeneration. ...Through lineage tracing of biliary epithelial cells (BECs), we show that BECs are a source of new hepatocytes and gain an Hnf4α(+)CK19(+) bi-phenotypic state in periportal regions and fibrotic septa. ...
In this study, we modeled human chronic liver injuries, in which such responses are blunted, without genetic manipulations, and assessed pot …
Regulatory networks defining EMT during cancer initiation and progression
De Craene B and Berx G. Nat Rev Cancer 2013 - Review. PMID 23344542
Epithelial to mesenchymal transition (EMT) is essential for driving plasticity during development, but is an unintentional behaviour of cells during cancer progression. The EMT-associated reprogramming of cells not only suggests that fundamental changes may occur to several regulatory networks but also that an intimate interplay exists between them. ...
Epithelial to mesenchymal transition (EMT) is essential for driving plasticity during development, but is an unintentional behaviour
Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Rognoni E and Watt FM. Trends Cell Biol 2018 - Review. PMID 29807713 Free PMC article.
Skin architecture and function depend on diverse populations of epidermal cells and dermal fibroblasts. Reciprocal communication between the epidermis and dermis plays a key role in skin development, homeostasis and repair. While several stem cell populations have been identified in the epidermis with distinct locations and functions, it is now recognised that there is additional heterogeneity within the mesenchymal cells of the dermis. ...
Skin architecture and function depend on diverse populations of epidermal cells and dermal fibroblasts. Reciprocal communication betw …
Effect of human amniotic epithelial cells on pro-fibrogenic resident hepatic cells in a rat model of liver fibrosis.
Cargnoni A, et al. J Cell Mol Med 2018. PMID 29105277 Free PMC article.
In liver fibrosis, myofibroblasts derive either from activation of hepatic stellate cells (HSC) and portal fibroblasts (PF), or from the activation of fibroblasts that originate from ductular epithelial cells undergoing epithelial-mesenchymal transition. ...The amniotic membrane and epithelial cells (hAEC) derived thereof have been shown to decrease hepatic myofibroblast levels in rodents with liver fibrosis. ...
In liver fibrosis, myofibroblasts derive either from activation of hepatic stellate cells (HSC) and portal fibroblasts (PF), or from …
Pathogenesis of influenza-induced acute respiratory distress syndrome
Short KR, et al. Lancet Infect Dis 2014 - Review. PMID 24239327
The most important part of the epithelial-endothelial barrier is the alveolar epithelium, strengthened by tight junctions. Influenza virus targets these epithelial cells, reducing sodium pump activity, damaging tight junctions, and killing infected cells. Infected epithelial cells produce cytokines that attract leucocytes--neutrophils and macrophages--and activate adjacent endothelial cells. ...
The most important part of the epithelial-endothelial barrier is the alveolar epithelium, strengthened by tight junctions. Influenza …
Epithelial-to-Mesenchymal and Mesenchymal-to-Epithelial Transition in Mesenchymal Tumors: A Paradox in Sarcomas?
Sannino G, et al. Cancer Res 2017 - Review. PMID 28811330 Free article.
The epithelial-to-mesenchymal transition (EMT) is a reversible process comprised of various subprograms via which epithelial cells reduce their intercellular adhesions and proliferative capacity while gaining a mesenchymal phenotype with increased migratory and invasive properties. This process has been well described in several carcinomas, which are cancers of epithelial origin, and is crucial to metastatic tumor cell dissemination and drug resistance. ...
The epithelial-to-mesenchymal transition (EMT) is a reversible process comprised of various subprograms via which epithelial
Epithelial to Mesenchymal Transition (EMT) and Endothelial to Mesenchymal Transition (EndMT): Role and Implications in Kidney Fibrosis.
Cruz-Solbes AS and Youker K. Results Probl Cell Differ 2017 - Review. PMID 28409352
This chapter will discuss in detail the concept of epithelial to mesenchymal transition (EMT) and endothelial to mesenchymal transition (EndMT) in the context of fibrosis and kidney disease. ...
This chapter will discuss in detail the concept of epithelial to mesenchymal transition (EMT) and endothelial to mesenchymal transiti …
The role of endothelial cells in the vasculopathy of systemic sclerosis: A systematic review.
Mostmans Y, et al. Autoimmun Rev 2017 - Review. PMID 28572048
In this study, all English speaking articles concerning the role of endothelial cells (ECs) in SSc vasculopathy and representing biomarkers are systematically reviewed and categorized according to endothelial cell (EC) (dys)function in SSc. ...Finally, myofibroblasts involved in tissue fibrosis in SSc can derive from ECs or epithelial cells through a process known as endothelial-to-mesenchymal transition. ...
In this study, all English speaking articles concerning the role of endothelial cells (ECs) in SSc vasculopathy and representing biom …
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