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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
2006 1
2008 3
2009 8
2010 149
2011 513
2012 715
2013 878
2014 1011
2015 1201
2016 1292
2017 1315
2018 1261
2019 631
2020 7
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7,755 results
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Page 1
Molecular mechanisms of epithelial-mesenchymal transition.
Lamouille S, et al. Nat Rev Mol Cell Biol 2014 - Review. PMID 24556840 Free PMC article.
The transdifferentiation of epithelial cells into motile mesenchymal cells, a process known as epithelial-mesenchymal transition (EMT), is integral in development, wound healing and stem cell behaviour, and contributes pathologically to fibrosis and cancer progression. ...
The transdifferentiation of epithelial cells into motile mesenchymal cells, a process known as epithelial-mesenchyma
Signaling mechanisms of the epithelial-mesenchymal transition.
Gonzalez DM and Medici D. Sci Signal 2014 - Review. PMID 25249658 Free PMC article.
The epithelial-mesenchymal transition (EMT) is an essential mechanism in embryonic development and tissue repair. EMT also contributes to the progression of disease, including organ fibrosis and cancer. EMT, as well as a similar transition occurring in vascular endothelial cells called endothelial-mesenchymal transition (EndMT), results from the induction of transcription factors that alter gene expression to promote loss of cell-cell adhesion, leading to a shift in cytoskeletal dynamics and a change from epithelial morphology and physiology to the mesenchymal phenotype. ...
The epithelial-mesenchymal transition (EMT) is an essential mechanism in embryonic development and tissue repair. EMT a …
Epithelial-to-mesenchymal transition in cancer: complexity and opportunities.
Zhang Y and Weinberg RA. Front Med 2018 - Review. PMID 30043221 Free PMC article.
The cell-biological program termed the epithelial-to-mesenchymal transition (EMT) plays an important role in both development and cancer progression. Depending on the contextual signals and intracellular gene circuits of a particular cell, this program can drive fully epithelial cells to enter into a series of phenotypic states arrayed along the epithelial-mesenchymal phenotypic axis. ...
The cell-biological program termed the epithelial-to-mesenchymal transition (EMT) plays an important role in both devel …
Mesenchymal-epithelial transition in development and reprogramming.
Pei D, et al. Nat Cell Biol 2019 - Review. PMID 30602762
During organogenesis, epithelial cells can give rise to mesenchymal cells through epithelial-mesenchymal transition. The reverse process, mesenchymal-epithelial transition (MET), can similarly generate epithelial cells. Transitions between epithelial and mesenchymal states are also critical for the induction of pluripotent stem cells from somatic cells. ...
During organogenesis, epithelial cells can give rise to mesenchymal cells through epithelial-mesenchymal tran
New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer.
Dongre A and Weinberg RA. Nat Rev Mol Cell Biol 2019 - Review. PMID 30459476
Epithelial-mesenchymal transition (EMT) is a cellular programme that is known to be crucial for embryogenesis, wound healing and malignant progression. ...We also highlight how EMT gives rise to a variety of intermediate cell states between the epithelial and the mesenchymal state, which could function as cancer stem cells. ...
Epithelial-mesenchymal transition (EMT) is a cellular programme that is known to be crucial for embryogenesis, wound he
Epithelial Mesenchymal Transition in Tumor Metastasis.
Mittal V. Annu Rev Pathol 2018 - Review. PMID 29414248
Epithelial mesenchymal transition (EMT), an evolutionarily conserved developmental program, has been implicated in carcinogenesis and confers metastatic properties upon cancer cells by enhancing mobility, invasion, and resistance to apoptotic stimuli. ...
Epithelial mesenchymal transition (EMT), an evolutionarily conserved developmental program, has been implicated in carc
Epithelial-mesenchymal transition (EMT) and metastasis: yes, no, maybe?
Diepenbruck M and Christofori G. Curr Opin Cell Biol 2016 - Review. PMID 27371787
An epithelial to mesenchymal transition (EMT) is a process of cell remodeling critical during embryonic development and organogenesis. During an EMT, epithelial cells lose their polarized organization and acquire migratory and invasive capabilities. While a plethora of experimental results have indicated that manipulating an EMT also affects cancer metastasis, its reverse process, a mesenchymal to epithelial transition (MET), seems to support metastatic outgrowth in distant organs. ...
An epithelial to mesenchymal transition (EMT) is a process of cell remodeling critical during embryonic development and …
Epithelial-mesenchymal transition in tissue repair and fibrosis.
Stone RC, et al. Cell Tissue Res 2016 - Review. PMID 27461257 Free PMC article.
The epithelial-mesenchymal transition (EMT) describes the global process by which stationary epithelial cells undergo phenotypic changes, including the loss of cell-cell adhesion and apical-basal polarity, and acquire mesenchymal characteristics that confer migratory capacity. EMT and its converse, MET (mesenchymal-epithelial transition), are integral stages of many physiologic processes and, as such, are tightly coordinated by a host of molecular regulators. ...
The epithelial-mesenchymal transition (EMT) describes the global process by which stationary epithelial cells un …
Targeting Epithelial-Mesenchymal Transition (EMT) to Overcome Drug Resistance in Cancer.
Du B and Shim JS. Molecules 2016 - Review. PMID 27455225 Free PMC article.
Epithelial-mesenchymal transition (EMT) is known to play an important role in cancer progression, metastasis and drug resistance. ...
Epithelial-mesenchymal transition (EMT) is known to play an important role in cancer progression, metastasis and drug r
Epithelial-mesenchymal transition: a new target in anticancer drug discovery.
Marcucci F, et al. Nat Rev Drug Discov 2016. PMID 26822829
The conversion of cells with an epithelial phenotype into cells with a mesenchymal phenotype, referred to as epithelial-mesenchymal transition, is a critical process for embryonic development that also occurs in adult life, particularly during tumour progression. ...Epithelial-mesenchymal transition is therefore becoming a target of prime interest for anticancer therapy. Here, we discuss the screening and classification of compounds that affect epithelial-mesenchymal transition, highlight some compounds of particular interest, and address issues related to their clinical application....
The conversion of cells with an epithelial phenotype into cells with a mesenchymal phenotype, referred to as epithelial
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