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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1997 2
1999 5
2005 28
2006 80
2007 140
2008 189
2009 177
2010 147
2011 149
2012 149
2013 155
2014 148
2015 138
2016 151
2017 132
2018 101
2019 44
2020 2
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1,644 results
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Page 1
Modern diagnosis of GERD: the Lyon Consensus
Gyawali CP, et al. Gut 2018 - Review. PMID 29437910 Free PMC article.
Conclusive evidence for reflux on oesophageal testing include advanced grade erosive oesophagitis (LA grades C and D), long-segment Barrett's mucosa or peptic strictures on endoscopy or distal oesophageal acid exposure time (AET) >6% on ambulatory pH or pH-impedance monitoring. A normal endoscopy does not exclude GERD, but provides supportive evidence refuting GERD in conjunction with distal AET <4% and <40 reflux episodes on pH-impedance monitoring off proton pump inhibitors. ...
Conclusive evidence for reflux on oesophageal testing include advanced grade erosive oesophagitis (LA grades C and D), long-segment Barrett' …
Ambulatory reflux monitoring for diagnosis of gastro-esophageal reflux disease: Update of the Porto consensus and recommendations from an international consensus group.
Roman S, et al. Neurogastroenterol Motil 2017 - Review. PMID 28370768
BACKGROUND: An international group of experts evaluated and revised recommendations for ambulatory reflux monitoring for the diagnosis of gastro-esophageal reflux disease (GERD). ...In this setting, testing can be either catheter-based or wireless pH-monitoring or pH-impedance monitoring. In patients with a high probability of GERD (esophagitis grade C and D, histology proven Barrett's mucosa >1 cm, peptic stricture, previous positive pH monitoring) and persistent symptoms, pH-impedance monitoring should be performed on treatment. ...
BACKGROUND: An international group of experts evaluated and revised recommendations for ambulatory reflux monitoring for the diagnosi …
Simultaneous laryngopharyngeal pH monitoring (Restech) and conventional esophageal pH monitoring-correlation using a large patient cohort of more than 100 patients with suspected gastroesophageal reflux disease.
Fuchs HF, et al. Dis Esophagus 2018. PMID 29534167
24-hour esophageal pH-metry is not designed to detect laryngopharyngeal reflux (LPR). The new laryngopharyngeal pH-monitoring system (Restech) may detect LPR better. ...Consecutive patients with suspected gastroesophageal reflux and disease-related extra-esophageal symptoms were evaluated using 24-hour laryngopharyngeal and concomitant esophageal pH-monitoring. ...
24-hour esophageal pH-metry is not designed to detect laryngopharyngeal reflux (LPR). The new laryngopharyngeal pH-m
Impedance-pH Monitoring for Diagnosis of Reflux Disease: New Perspectives.
Frazzoni M, et al. Dig Dis Sci 2017 - Review. PMID 28550489
Thus, since normal findings at upper endoscopy are detected in the majority of patients with heartburn, reflux monitoring is often required. ...Combined impedance-pH monitoring has the advantage to provide a comprehensive assessment of both physical and chemical properties of refluxate and the distinction between acid and weakly acidic refluxes, both proven to cause heartburn. ...
Thus, since normal findings at upper endoscopy are detected in the majority of patients with heartburn, reflux monitoring is often re …
Indications of 24-h esophageal pH monitoring, capsule pH monitoring, combined pH monitoring with multichannel impedance, esophageal manometry, radiology and scintigraphy in gastroesophageal reflux disease?
Vardar R and Keskin M. Turk J Gastroenterol 2017 - Review. PMID 29199161 Free article.
Ambulatory esophageal pH monitoring is an essential method in patients exhibiting signs of non-erosive reflux disease (NERD) to make an objective diagnosis. ...Ambulatory esophageal pH monitoring can be detected within normal limits in 17%-31.4% of the patients with endoscopic esophagitis; therefore, normal pH monitoring cannot exclude the diagnosis of gastroesophageal reflux disease (GERD). ...
Ambulatory esophageal pH monitoring is an essential method in patients exhibiting signs of non-erosive reflux disease ( …
The role of esophageal pH-impedance testing in clinical practice.
Hobbs P and Gyawali CP. Curr Opin Gastroenterol 2018 - Review. PMID 29846260
Although pH-based metrics have been the standard in defining esophageal reflux burden, novel impedance parameters have been introduced in recent years that can either be extracted from pH-impedance monitoring or obtained directly from esophageal mucosa. ...SUMMARY: Esophageal pH-impedance monitoring has potential to augment confidence in a reflux diagnosis beyond that provided by pH-monitoring alone....
Although pH-based metrics have been the standard in defining esophageal reflux burden, novel impedance parameters have been in …
Ambulatory esophageal pH monitoring.
Han MS and Peters JH. Gastrointest Endosc Clin N Am 2014 - Review. PMID 25216904
The development and advancement of ambulatory esophageal pH monitoring has provided a key tool with which pathologic esophageal acid exposure can be objectively measured; although not perfect, it provides the clinician with arguably the most important piece of information in the diagnosis and management of patients with gastroesophageal reflux disease. It is also important to emphasize that, although esophageal pH monitoring can reliably measure esophageal acid exposure, assessing the relationship of abnormal findings and the patients' symptoms is a much more complex matter and, of course, the key to successful treatment outcomes....
The development and advancement of ambulatory esophageal pH monitoring has provided a key tool with which pathologic …
Does DeMeester score still define GERD?
Neto RML, et al. Dis Esophagus 2019 - Review. PMID 30561585
Gastroesophageal reflux disease (GERD) clinical presentation may encompass a myriad of symptoms that may mimic other esophageal and extra-esophageal diseases. ...Upper digestive endoscopy and barium esophagram may also be misleading. pH monitoring must be added often for a definitive diagnosis. ...
Gastroesophageal reflux disease (GERD) clinical presentation may encompass a myriad of symptoms that may mimic other esophageal and e …
Esophageal impedance-pH monitoring.
Sifrim D and Fornari F. Dig Liver Dis 2008 - Review. PMID 18082474
Ambulatory esophageal impedance-pH monitoring is a new technique that can be used to evaluate all types of gastroesophageal reflux, achieving higher rates of sensitivity and specificity than standard techniques. This review describes esophageal impedance-pH monitoring, summarizing the current literature on validation studies and clinical application....
Ambulatory esophageal impedance-pH monitoring is a new technique that can be used to evaluate all types of gastroesopha …
pH Impedance vs. traditional pH monitoring in clinical practice: an outcome study.
Pugliese D, et al. J Gastroenterol 2016 - Clinical Trial. PMID 26033511
BACKGROUND: The addition of impedance to 24-h pH monitoring has allowed detection of weakly acidic reflux, but the extent to which pH-impedance (pH-MII) monitoring improves outcomes is unknown. ...CONCLUSIONS: Two-thirds of patients undergoing pH-MII monitoring experience a positive outcome, similarly to what occurs after traditional pH monitoring. ...
BACKGROUND: The addition of impedance to 24-h pH monitoring has allowed detection of weakly acidic reflux, but the extent to w …
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