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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1959 3
1960 5
1961 1
1962 3
1963 2
1964 1
1967 1
1977 3
1979 1
1980 6
1981 5
1982 17
1983 18
1984 10
1985 24
1986 31
1987 42
1988 48
1989 65
1990 144
1991 329
1992 384
1993 476
1994 560
1995 597
1996 571
1997 555
1998 620
1999 626
2000 671
2001 712
2002 740
2003 746
2004 890
2005 847
2006 909
2007 858
2008 846
2009 836
2010 940
2011 942
2012 935
2013 833
2014 898
2015 788
2016 706
2017 690
2018 652
2019 291
2020 7
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19,153 results
Results by year
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Page 1
Antibodies and methods for immunohistochemistry of extracellular matrix proteins.
Rickelt S and Hynes RO. Matrix Biol 2018 - Review. PMID 29730502
The diversity of extracellular matrix (ECM) proteins encoded in mammalian genomes and detected by proteomic analyses generates a need for well validated antibodies against these proteins. ...These data should be of value to investigators seeking well validated antibodies to ECM proteins of interest and save significant time and money tracking down effective reagents....
The diversity of extracellular matrix (ECM) proteins encoded in mammalian genomes and detected by proteomic analyses ge …
Cardiac Extracellular Matrix Modification as a Therapeutic Approach.
Hall ML and Ogle BM. Adv Exp Med Biol 2018 - Review. PMID 30238369 Free PMC article.
The cardiac extracellular matrix (cECM) is comprised of proteins and polysaccharides secreted by cardiac cell types, which provide structural and biochemical support to cardiovascular tissue. ...However, the complexity of tissues makes it difficult to isolate the effects of individual cECM proteins on a particular cell process or disease state. ...
The cardiac extracellular matrix (cECM) is comprised of proteins and polysaccharides secreted by cardiac cell types, wh …
Phosphorylation of Extracellular Bone Matrix Proteins and Its Contribution to Bone Fragility.
Sroga GE and Vashishth D. J Bone Miner Res 2018. PMID 30001467 Free article.
Here for the first time, we report that as people age the total phosphorylation level declines by approximately 20% for bone matrix proteins and approximately 30% for OPN in the ninth decade of human life. Moreover, our results suggest that the decline of total protein phosphorylation of extracellular matrix (ECM) contributes to bone fragility, but less pronouncedly than glycation. ...
Here for the first time, we report that as people age the total phosphorylation level declines by approximately 20% for bone matrix
Role of Liquid-Liquid Phase Separation in Assembly of Elastin and Other Extracellular Matrix Proteins.
Muiznieks LD, et al. J Mol Biol 2018 - Review. PMID 29886015
Phase separation also appears to be a widespread and evolutionarily ancient mechanism for organization of proteins of the extracellular matrix into fibrillar, polymeric assemblies. Elastin, which provides the physical properties of extensibility and elastic recoil to large arteries, lungs and other tissues, is the best-characterized extracellular matrix protein whose polymeric assembly is initiated by phase separation. ...
Phase separation also appears to be a widespread and evolutionarily ancient mechanism for organization of proteins of the extracel
The Complex Interplay Between Extracellular Matrix and Cells in Tissues.
Manou D, et al. Methods Mol Biol 2019 - Review. PMID 30825161
Extracellular matrix (ECM) maintains the structural integrity of tissues and regulates cell and tissue functions. ECM is comprised of fibrillar proteins, proteoglycans (PGs), glycosaminoglycans, and glycoproteins, creating a heterogeneous but well-orchestrated network. ...The interplay of ECM with recipient cells is enriched by the extracellular vesicles, as they accommodate ECM, signaling, and cytoskeleton molecules in their cargo. ...
Extracellular matrix (ECM) maintains the structural integrity of tissues and regulates cell and tissue functions. ECM is compr
Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer.
Andriani F, et al. BMC Cancer 2018. PMID 30227835 Free PMC article.
During this process, bi-directional communication among tumor cells and cancer associated fibroblasts (CAF) regulate extracellular matrix (ECM) deposition and remodeling. ...Soluble ECM proteins were assessed by western blot in the conditioned medium of lung fibroblasts and by ELISA assays in plasma samples. ...
During this process, bi-directional communication among tumor cells and cancer associated fibroblasts (CAF) regulate extracellular
Extracellular matrix protein 1 promotes follicular helper T cell differentiation and antibody production.
He L, et al. Proc Natl Acad Sci U S A 2018. PMID 30087185 Free PMC article.
Whether important extracellular molecules control T(FH) differentiation is not fully understood. Here, we demonstrate that a secreted protein extracellular matrix protein 1 (ECM1) is critical for T(FH) differentiation and antibody response. ...
Whether important extracellular molecules control T(FH) differentiation is not fully understood. Here, we demonstrate that a secreted …
Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex.
Long KR, et al. Neuron 2018. PMID 30078576 Free article.
Extracellular matrix (ECM) has been previously implicated in neocortical expansion and here we investigate the potential role of ECM in the formation of neocortical folds. ...
Extracellular matrix (ECM) has been previously implicated in neocortical expansion and here we investigate the potential role
SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis.
Athwal VS, et al. Sci Rep 2018. PMID 30559459 Free PMC article.
Extracellular matrix (ECM) deposition and resultant scar play a major role in the pathogenesis and progression of liver fibrosis. ...In patient serum samples, SOX9-regulated ECM proteins were altered in response to fibrosis severity, whereas comparison with established clinical biomarkers demonstrated superiority for OPN and VIM at detecting early stages of fibrosis. ...
Extracellular matrix (ECM) deposition and resultant scar play a major role in the pathogenesis and progression of liver fibros
19,153 results
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