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Phase IV Multicenter, Prospective, Open-Label Clinical Trial of Cenegermin (rhNGF) for Stage 1 Neurotrophic Keratopathy (DEFENDO).
Hamrah P, Massaro-Giordano M, Schanzlin D, Holland E, Berdy G, Goisis G, Pasedis G, Mantelli F. Hamrah P, et al. Ophthalmol Ther. 2024 Feb;13(2):553-570. doi: 10.1007/s40123-023-00866-y. Epub 2024 Jan 4. Ophthalmol Ther. 2024. PMID: 38175466 Free PMC article.
The most common treatment-related, treatment-emergent AEs were eye pain (37.8%), blurred vision (10.8%), and eyelid pain (8.1%); these were mostly mild or moderate and were only reported during the treatment period. ...
The most common treatment-related, treatment-emergent AEs were eye pain (37.8%), blurred vision (10.8%), and eyelid pain (8.1% …
Inflammatory Reaction to Decellularized Porcine-Derived Xenograft for Lower Eyelid Retraction.
Mancera N, Schneider A, Margo CE, Bajric J. Mancera N, et al. Ophthalmic Plast Reconstr Surg. 2019 Jul/Aug;35(4):e95-e97. doi: 10.1097/IOP.0000000000001416. Ophthalmic Plast Reconstr Surg. 2019. PMID: 31206458
A 54-year-old woman underwent uncomplicated bilateral lower eyelid surgery for eyelid retraction using porcine decellularized membrane graft (TarSys). Left lower eyelid pain began several months after surgery and persisted until the graft was removed 15 months after …
A 54-year-old woman underwent uncomplicated bilateral lower eyelid surgery for eyelid retraction using porcine decellularized membrane graft …
Real-World Safety Profile of Cenegermin Per FDA Adverse Event Reporting System.
Choudhry HS, Pei M, Mothy D, Scarfuto J, Mian SI. Choudhry HS, et al. J Ocul Pharmacol Ther. 2025 May 7. doi: 10.1089/jop.2025.0023. Online ahead of print. J Ocul Pharmacol Ther. 2025. PMID: 40329904
Of 34 eye disorders that were found to be associated with cenegermin use, the ones with the highest odds ratios were periorbital pain [ROR: 25.34, confidence interval (CI): 20.70-31.01, PRR: 16.45], eyelid pain (ROR: 22.96, CI: 19.39-27.19, PRR: 15.50), and eye pain …
Of 34 eye disorders that were found to be associated with cenegermin use, the ones with the highest odds ratios were periorbital pain [ROR: …
Outcomes and complications of hydrogel scleral explant removal.
Chen CJ, Kosek K, Benvenutti E. Chen CJ, et al. Ophthalmic Surg Lasers Imaging. 2012 Sep-Oct;43(5):383-7. doi: 10.3928/15428877-20120531-03. Epub 2012 Jun 7. Ophthalmic Surg Lasers Imaging. 2012. PMID: 22692642
Common complaints included limited ocular motility, presence of a palpable mass under the eyelid, pain and discomfort, diplopia, visible SB under eroded conjunctiva, complete immobility, and signs of infection. ...
Common complaints included limited ocular motility, presence of a palpable mass under the eyelid, pain and discomfort, diplopi …
Esophageal adenocarcinoma and urothelial carcinoma orbital metastases masquerading as infection.
Magrath GN, Proctor CM, Reardon WA, Patel KG, Lentsch EJ, Eiseman AS. Magrath GN, et al. Orbit. 2015 Feb;34(1):51-5. doi: 10.3109/01676830.2014.963879. Epub 2014 Oct 17. Orbit. 2015. PMID: 25325392
The first patient presented with left upper eyelid pain. CT scan identified a superolateral subperiosteal fluid collection without concomitant sinus disease, which was drained in the operating room. ...
The first patient presented with left upper eyelid pain. CT scan identified a superolateral subperiosteal fluid collection wit …
Clinical study of the radiotherapy with EDGE accelerator in the treatment of the moderate and severe thyroid associated ophthalmopathy.
Zeng L, Xie XQ, Li CH, Shi HS, Wang F. Zeng L, et al. Eur Rev Med Pharmacol Sci. 2019 Apr;23(8):3471-3477. doi: 10.26355/eurrev_201904_17712. Eur Rev Med Pharmacol Sci. 2019. PMID: 31081102 Free article.
After the radiotherapy, the patient's exophthalmia, soft tissue involvement, eye external muscle involvement, corneal involvement, decreased vision and diplopia, tearing and eyelid pain have improved. Acute complications included increased local inflammation, hair l …
After the radiotherapy, the patient's exophthalmia, soft tissue involvement, eye external muscle involvement, corneal involvement, decreased …
Crab lice infestation in unilateral eyelashes and adjacent eyelids: A case report.
Tang W, Li QQ. Tang W, et al. World J Clin Cases. 2021 Nov 26;9(33):10323-10327. doi: 10.12998/wjcc.v9.i33.10323. World J Clin Cases. 2021. PMID: 34904106 Free PMC article.
CASE SUMMARY: A 50-year-old woman presented to our hospital with a 2-wk history of chronic eyelid pain and itching in the right eye, which exacerbated in the evening hours and which had not resolved following a 1-wk course of antibiotics and corticosteroid ointments …
CASE SUMMARY: A 50-year-old woman presented to our hospital with a 2-wk history of chronic eyelid pain and itching in the righ …
Meta-analysis of the efficacy and safety of alpha2-adrenergic agonists, beta-adrenergic antagonists, and topical carbonic anhydrase inhibitors with prostaglandin analogs.
Tanna AP, Rademaker AW, Stewart WC, Feldman RM. Tanna AP, et al. Arch Ophthalmol. 2010 Jul;128(7):825-33. doi: 10.1001/archophthalmol.2010.131. Arch Ophthalmol. 2010. PMID: 20625041
Peak IOP reduction was similar in the 3 groups (P = .66). Eye or eyelid pain or burning and xerostomia were significantly more common in the AA group. Fatigue, weakness, or dizziness was more common in the AA and BB groups compared with the TCAI group. ...
Peak IOP reduction was similar in the 3 groups (P = .66). Eye or eyelid pain or burning and xerostomia were significantly more …
[Orbital cellulitis. A case report].
Tucciarone L, Colasanti A, Sabbi T, Papandrea S, Barbieri MA. Tucciarone L, et al. Minerva Pediatr. 1997 May;49(5):211-4. Minerva Pediatr. 1997. PMID: 9340483 Italian.
This study describes the case of a 6 years old child, male, with orbital cellulitis and underlines the importance of an early diagnosis and therapy to avoid severe complications often present in this disease. Swelling and redness of the eyelid, pain and ophthalmople …
This study describes the case of a 6 years old child, male, with orbital cellulitis and underlines the importance of an early diagnosis and …