"FTO protein, mouse"[nm] - Search Results

Year	Number of Results
2007	1
2008	5
2009	5
2010	8
2011	6
2012	5
2013	5
2014	11
2015	9
2016	10
2017	11
2018	15
2019	13
2020	14
2021	25
2022	28
2023	32
2024	14

1

FTO mediates LINE1 m⁶A demethylation and chromatin regulation in mESCs and mouse development.

Wei J, Yu X, Yang L, Liu X, Gao B, Huang B, Dou X, Liu J, Zou Z, Cui XL, Zhang LS, Zhao X, Liu Q, He PC, Sepich-Poore C, Zhong N, Liu W, Li Y, Kou X, Zhao Y, Wu Y, Cheng X, Chen C, An Y, Dong X, Wang H, Shu Q, Hao Z, Duan T, He YY, Li X, Gao S, Gao Y, He C. Wei J, et al. Science. 2022 May 27;376(6596):968-973. doi: 10.1126/science.abe9582. Epub 2022 May 5. Science. 2022. PMID: 35511947 Free PMC article.

2

FTO-Dependent N⁶-Methyladenosine Regulates Cardiac Function During Remodeling and Repair.

Mathiyalagan P, Adamiak M, Mayourian J, Sassi Y, Liang Y, Agarwal N, Jha D, Zhang S, Kohlbrenner E, Chepurko E, Chen J, Trivieri MG, Singh R, Bouchareb R, Fish K, Ishikawa K, Lebeche D, Hajjar RJ, Sahoo S. Mathiyalagan P, et al. Circulation. 2019 Jan 22;139(4):518-532. doi: 10.1161/CIRCULATIONAHA.118.033794. Circulation. 2019. PMID: 29997116 Free PMC article.

3

FTO and obesity: mechanisms of association.

Zhao X, Yang Y, Sun BF, Zhao YL, Yang YG. Zhao X, et al. Curr Diab Rep. 2014;14(5):486. doi: 10.1007/s11892-014-0486-0. Curr Diab Rep. 2014. PMID: 24627050 Review.

4

FTO-dependent m⁶A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.

Li B, Xi W, Bai Y, Liu X, Zhang Y, Li L, Bian L, Liu C, Tang Y, Shen L, Yang L, Gu X, Xie J, Zhou Z, Wang Y, Yu X, Wang J, Chao J, Han B, Yao H. Li B, et al. Nat Commun. 2023 Jan 30;14(1):489. doi: 10.1038/s41467-023-36008-y. Nat Commun. 2023. PMID: 36717587 Free PMC article.

5

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m⁶A/MYC/CEBPA Signaling.

Su R, Dong L, Li C, Nachtergaele S, Wunderlich M, Qing Y, Deng X, Wang Y, Weng X, Hu C, Yu M, Skibbe J, Dai Q, Zou D, Wu T, Yu K, Weng H, Huang H, Ferchen K, Qin X, Zhang B, Qi J, Sasaki AT, Plas DR, Bradner JE, Wei M, Marcucci G, Jiang X, Mulloy JC, Jin J, He C, Chen J. Su R, et al. Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14. Cell. 2018. PMID: 29249359 Free PMC article.

6

m⁶A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7.

Wang X, Wu R, Liu Y, Zhao Y, Bi Z, Yao Y, Liu Q, Shi H, Wang F, Wang Y. Wang X, et al. Autophagy. 2020 Jul;16(7):1221-1235. doi: 10.1080/15548627.2019.1659617. Epub 2019 Aug 26. Autophagy. 2020. PMID: 31451060 Free PMC article.

7

Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.

Liu Y, Liang G, Xu H, Dong W, Dong Z, Qiu Z, Zhang Z, Li F, Huang Y, Li Y, Wu J, Yin S, Zhang Y, Guo P, Liu J, Xi JJ, Jiang P, Han D, Yang CG, Xu MM. Liu Y, et al. Cell Metab. 2021 Jun 1;33(6):1221-1233.e11. doi: 10.1016/j.cmet.2021.04.001. Epub 2021 Apr 27. Cell Metab. 2021. PMID: 33910046 Free article.

8

Disruption of CerS6-mediated sphingolipid metabolism by FTO deficiency aggravates ulcerative colitis.

Ma Y, Zhang X, Xuan B, Li D, Yin N, Ning L, Zhou YL, Yan Y, Tong T, Zhu X, Huang X, Hu M, Wang Z, Cui Z, Li H, Wang J, Fang JY, Liu R, Chen H, Hong J. Ma Y, et al. Gut. 2024 Jan 5;73(2):268-281. doi: 10.1136/gutjnl-2023-330009. Gut. 2024. PMID: 37734910

9

m⁶A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.

Yang S, Wei J, Cui YH, Park G, Shah P, Deng Y, Aplin AE, Lu Z, Hwang S, He C, He YY. Yang S, et al. Nat Commun. 2019 Jun 25;10(1):2782. doi: 10.1038/s41467-019-10669-0. Nat Commun. 2019. PMID: 31239444 Free PMC article.

10

FTO promotes multiple myeloma progression by posttranscriptional activation of HSF1 in an m⁶A-YTHDF2-dependent manner.

Xu A, Zhang J, Zuo L, Yan H, Chen L, Zhao F, Fan F, Xu J, Zhang B, Zhang Y, Yin X, Cheng Q, Gao S, Deng J, Mei H, Huang Z, Sun C, Hu Y. Xu A, et al. Mol Ther. 2022 Mar 2;30(3):1104-1118. doi: 10.1016/j.ymthe.2021.12.012. Epub 2021 Dec 13. Mol Ther. 2022. PMID: 34915192 Free PMC article.

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