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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
1957 5
1958 4
1959 1
1963 1
1964 5
1965 43
1966 69
1967 110
1968 110
1969 139
1970 160
1971 152
1972 145
1973 153
1974 153
1975 144
1976 104
1977 135
1978 82
1979 99
1980 78
1981 82
1982 106
1983 101
1984 93
1985 119
1986 108
1987 95
1988 86
1989 78
1990 80
1991 75
1992 58
1993 58
1994 59
1995 79
1996 61
1997 86
1998 79
1999 108
2000 112
2001 159
2002 169
2003 207
2004 253
2005 352
2006 407
2007 478
2008 544
2009 650
2010 791
2011 809
2012 915
2013 1000
2014 1140
2015 1237
2016 1330
2017 1325
2018 1330
2019 680
2020 7
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15,763 results
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Page 1
Pathophysiology of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis.
Manne V, et al. Clin Liver Dis 2018 - Review. PMID 29128059
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of liver disorders ranging from hepatic steatosis to nonalcoholic steatohepatitis (NASH) and ultimately may lead to cirrhosis. Hepatic steatosis or fatty liver is defined as increased accumulation of lipids in hepatocytes and results from increased production or reduced clearance of hepatic triglycerides or fatty acids. ...
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of liver disorders ranging from hepatic steatosis to no …
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD).
Buzzetti E, et al. Metabolism 2016 - Review. PMID 26823198
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing challenge in terms of prevention and treatment. Despite its high prevalence, only a small minority of affected patients develops inflammation and subsequently fibrosis and chronic liver disease, while most of them only exhibit simple steatosis. ...
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing challenge in terms of prevention a …
The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.
Kazankov K, et al. Nat Rev Gastroenterol Hepatol 2019 - Review. PMID 30482910
Nonalcoholic fatty liver disease (NAFLD) and its inflammatory and often progressive subtype nonalcoholic steatohepatitis (NASH) are becoming the leading cause of liver-related morbidity and mortality worldwide, and a primary indication for liver transplantation. ...Macrophage activation is mediated by factors such as endotoxins and translocated bacteria owing to increased intestinal permeability, factors released from damaged or lipoapoptotic hepatocytes, as well as alterations in gut microbiota and defined nutritional components, including certain free fatty acids, cholesterol and their metabolites. ...
Nonalcoholic fatty liver disease (NAFLD) and its inflammatory and often progressive subtype nonalcoholic steatohepatitis (NASH …
Animal Models of Nonalcoholic Fatty Liver Disease-A Starter's Guide.
Van Herck MA, et al. Nutrients 2017 - Review. PMID 28953222 Free PMC article.
Nonalcoholic fatty liver disease (NAFLD) constitutes a major health concern with the increasing incidence of obesity and diabetes in many Western countries, reaching a prevalence of up to 30% in the general population. ...
Nonalcoholic fatty liver disease (NAFLD) constitutes a major health concern with the increasing incidence of obesity and diabe …
Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum.
Hardy T, et al. Annu Rev Pathol 2016 - Review. PMID 26980160
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver dysfunction in the Western world and is increasing owing to its close association with obesity and insulin resistance. NAFLD represents a spectrum of liver disease that, in a minority of patients, can lead to progressive nonalcoholic steatohepatitis (NASH), fibrosis, and ultimately hepatocellular carcinoma and liver failure. ...
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver dysfunction in the Western world and is incr …
Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome.
Yki-Järvinen H. Lancet Diabetes Endocrinol 2014 - Review. PMID 24731669
Metabolic syndrome is a cluster of metabolic abnormalities that identifies people at risk of diabetes and cardiovascular disease, whereas non-alcoholic fatty liver disease (NAFLD) is defined as a disorder with excess fat in the liver due to non-alcoholic causes. Two key components of metabolic syndrome, glucose and triglycerides, are overproduced by the fatty liver. The liver is therefore a key determinant of metabolic abnormalities. ...
Metabolic syndrome is a cluster of metabolic abnormalities that identifies people at risk of diabetes and cardiovascular disease, whereas no …
Transient elastography (FibroScan(®)) with controlled attenuation parameter in the assessment of liver steatosis and fibrosis in patients with nonalcoholic fatty liver disease - Where do we stand?
Mikolasevic I, et al. World J Gastroenterol 2016 - Review. PMID 27621571 Free PMC article.
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Currently, the routinely used modalities are unable to adequately determine the levels of steatosis and fibrosis (laboratory tests and ultrasonography) or cannot be applied as a screening procedure (liver biopsy). ...Its ability to exclude patients with advanced fibrosis may be used to identify low-risk NAFLD patients in whom liver biopsy is not needed, therefore reducing the risk of complications and the financial costs....
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Currently, the r …
Pathological features of fatty liver disease.
Yeh MM and Brunt EM. Gastroenterology 2014 - Review. PMID 25109884
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are significant causes of chronic liver disease worldwide. ...Although steatosis can be a significant cofactor in progression of established chronic liver disease, or even development of hepatocellular carcinoma, only steatohepatitis indicates the presence of progressive liver disease in patients with NAFLD. ...
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are significant causes of chronic liver
Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives.
Arab JP, et al. Hepatology 2017 - Review. PMID 27358174 Free PMC article.
Nonalcoholic fatty liver disease (NAFLD) is a burgeoning health problem worldwide and an important risk factor for both hepatic and cardiometabolic mortality. ...
Nonalcoholic fatty liver disease (NAFLD) is a burgeoning health problem worldwide and an important risk factor for both hepati …
Histopathology of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.
Brown GT and Kleiner DE. Metabolism 2016 - Review. PMID 26775559 Free PMC article.
Nonalcoholic fatty liver disease (NAFLD) is the liver injury most often associated with disorders of insulin resistance, including obesity, diabetes and the metabolic syndrome. The term encompasses several patterns of liver injury, including a relatively benign condition of steatosis without hepatocellular injury, nonalcoholic steatohepatitis (NASH), and a pattern of zone 1 steatosis, inflammation and fibrosis mainly observed in prepubertal children. ...
Nonalcoholic fatty liver disease (NAFLD) is the liver injury most often associated with disorders of insulin resistance …
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