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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1999 1
2000 3
2002 2
2003 1
2005 2
2006 2
2007 1
2009 1
2010 1
2014 1
2016 1
2017 2
2018 3
2019 2
2020 1
2021 0
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20 results
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Page 1
Fetal valproate syndrome: the Irish experience.
Mohd Yunos H, Green A. Mohd Yunos H, et al. Ir J Med Sci. 2018 Nov;187(4):965-968. doi: 10.1007/s11845-018-1757-6. Epub 2018 Feb 3. Ir J Med Sci. 2018. PMID: 29396778
INTRODUCTION: Fetal valproate syndrome was first described in 1984. Valproic acid crosses the placenta and can potentially lead to major congenital malformation, dysmorphism and neurodevelopmental disorder. METHODS: A retrospective study of 29 cases of FVS diagnosed …
INTRODUCTION: Fetal valproate syndrome was first described in 1984. Valproic acid crosses the placenta and can potentially lea …
The importance of monotherapy in pregnancy.
Pennell PB. Pennell PB. Neurology. 2003 Jun 10;60(11 Suppl 4):S31-8. doi: 10.1212/wnl.60.11_suppl_4.s31. Neurology. 2003. PMID: 12796519 Review.
Various combinations of these findings can occur in an individual infant and are referred to as the fetal anticonvulsant syndrome (FAS). The most common major malformations are cleft lip/palate, heart defects, neural tube defects, and urogenital defects. ...
Various combinations of these findings can occur in an individual infant and are referred to as the fetal anticonvulsant sy
Characteristics of fetal anticonvulsant syndrome associated autistic disorder.
Rasalam AD, Hailey H, Williams JH, Moore SJ, Turnpenny PD, Lloyd DJ, Dean JC. Rasalam AD, et al. Dev Med Child Neurol. 2005 Aug;47(8):551-5. doi: 10.1017/s0012162205001076. Dev Med Child Neurol. 2005. PMID: 16108456 Free article.
The aim of this study was to evaluate the clinical features and frequency of autistic disorder or Asperger syndrome (AS; according to Diagnostic and Statistical Manual of Mental Disorders, 4th edition [DSM-IV] criteria) in children exposed to anticonvulsant medicati …
The aim of this study was to evaluate the clinical features and frequency of autistic disorder or Asperger syndrome (AS; according to …
Fetal anticonvulsant syndrome and mutation in the maternal MTHFR gene.
Dean JC, Moore SJ, Osborne A, Howe J, Turnpenny PD. Dean JC, et al. Clin Genet. 1999 Sep;56(3):216-20. doi: 10.1034/j.1399-0004.1999.560306.x. Clin Genet. 1999. PMID: 10563481
We investigated the common 677 C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in samples from 57 patients and their parents and 152 controls to determine its contribution to the risk of fetal anticonvulsant syndrome. The 677 C>T mu …
We investigated the common 677 C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in samples from 57 patients and their …
Intellectual functioning in clinically confirmed fetal valproate syndrome.
Bromley RL, Baker GA, Clayton-Smith J, Wood AG. Bromley RL, et al. Neurotoxicol Teratol. 2019 Jan-Feb;71:16-21. doi: 10.1016/j.ntt.2018.11.003. Epub 2018 Nov 16. Neurotoxicol Teratol. 2019. PMID: 30453023
BACKGROUND: An increased risk of impaired intelligence (IQ) has been documented in valproate-exposed children, but investigations have not previously focused on those with a clinical diagnosis of Fetal Valproate Syndrome (FVS). METHODS: This cross sectional observat …
BACKGROUND: An increased risk of impaired intelligence (IQ) has been documented in valproate-exposed children, but investigations have not p …
Ophthalmic findings in fetal anticonvulsant syndrome(s).
Glover SJ, Quinn AG, Barter P, Hart J, Moore SJ, Dean JC, Turnpenny PD. Glover SJ, et al. Ophthalmology. 2002 May;109(5):942-7. doi: 10.1016/s0161-6420(02)00959-4. Ophthalmology. 2002. PMID: 11986102
PURPOSE: To report the prevalence of ocular abnormalities in a group of children diagnosed with fetal anticonvulsant (FAC) syndrome(s). DESIGN: Retrospective, observational, noncomparative case series. ...CONCLUSIONS: We conclude that (1) abnormal ophthalmic …
PURPOSE: To report the prevalence of ocular abnormalities in a group of children diagnosed with fetal anticonvulsant (FAC) …
Pregnancy in the woman with epilepsy: maternal and fetal outcomes.
Pennell PB. Pennell PB. Semin Neurol. 2002 Sep;22(3):299-308. doi: 10.1055/s-2002-36649. Semin Neurol. 2002. PMID: 12528055 Review.
Periodic monitoring of total and free AED levels is recommended. The "fetal anticonvulsant syndrome" has been described with all of the AEDs and includes major malformations, minor anomalies, microcephaly, cognitive impairment, intrauterine growth retardation …
Periodic monitoring of total and free AED levels is recommended. The "fetal anticonvulsant syndrome" has been described …
Exome sequencing in patients with antiepileptic drug exposure and complex phenotypes.
Jackson A, Ward H, Bromley RL, Deshpande C, Vasudevan P, Scurr I, Dean J, Shannon N, Berg J, Holder S, Baralle D, Clayton-Smith J; DDD Study. Jackson A, et al. Arch Dis Child. 2020 Apr;105(4):384-389. doi: 10.1136/archdischild-2018-316547. Epub 2019 Sep 3. Arch Dis Child. 2020. PMID: 31481360
INTRODUCTION: Fetal anticonvulsant syndrome (FACS) describes the pattern of physical and developmental problems seen in those children exposed to certain antiepileptic drugs (AEDs) in utero. ...
INTRODUCTION: Fetal anticonvulsant syndrome (FACS) describes the pattern of physical and developmental problems seen in …
5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review.
Botto LD, Yang Q. Botto LD, et al. Am J Epidemiol. 2000 May 1;151(9):862-77. doi: 10.1093/oxfordjournals.aje.a010290. Am J Epidemiol. 2000. PMID: 10791559 Review.
Studies of the C677T allele in relation to oral clefts, Down syndrome, and fetal anticonvulsant syndrome either have yielded conflicting results or have not been yet replicated....
Studies of the C677T allele in relation to oral clefts, Down syndrome, and fetal anticonvulsant syndrome either …
Fetal anticonvulsant syndrome in rats: dose- and period-response relationships of prenatal diphenylhydantoin, trimethadione and phenobarbital exposure on the structural and functional development of the offspring.
Vorhees CV. Vorhees CV. J Pharmacol Exp Ther. 1983 Nov;227(2):274-87. J Pharmacol Exp Ther. 1983. PMID: 6195326
Three experiments were performed in order to develop a murine model of the postnatal functional defects recently described in humans as the fetal anticonvulsant syndromes. In the first experiment, the lower end of the malformation dose-response curves for diphenylhy …
Three experiments were performed in order to develop a murine model of the postnatal functional defects recently described in humans as the …
20 results