Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1999 1
2000 2
2002 2
2003 1
2004 1
2005 2
2006 2
2007 1
2009 1
2010 1
2014 1
2017 1
2018 3
2019 2
2020 1
2021 0
Text availability
Article attribute
Article type
Publication date

Search Results

19 results
Results by year
Filters applied: . Clear all
Page 1
Fetal valproate syndrome: the Irish experience.
Mohd Yunos H, Green A. Mohd Yunos H, et al. Ir J Med Sci. 2018 Nov;187(4):965-968. doi: 10.1007/s11845-018-1757-6. Epub 2018 Feb 3. Ir J Med Sci. 2018. PMID: 29396778
INTRODUCTION: Fetal valproate syndrome was first described in 1984. Valproic acid crosses the placenta and can potentially lead to major congenital malformation, dysmorphism and neurodevelopmental disorder. METHODS: A retrospective study of 29 cases of FVS diagnosed …
INTRODUCTION: Fetal valproate syndrome was first described in 1984. Valproic acid crosses the placenta and can potentially lea …
The importance of monotherapy in pregnancy.
Pennell PB. Pennell PB. Neurology. 2003 Jun 10;60(11 Suppl 4):S31-8. doi: 10.1212/wnl.60.11_suppl_4.s31. Neurology. 2003. PMID: 12796519 Review.
Various combinations of these findings can occur in an individual infant and are referred to as the fetal anticonvulsant syndrome (FAS). The most common major malformations are cleft lip/palate, heart defects, neural tube defects, and urogenital defects. ...
Various combinations of these findings can occur in an individual infant and are referred to as the fetal anticonvulsant sy
Characteristics of fetal anticonvulsant syndrome associated autistic disorder.
Rasalam AD, Hailey H, Williams JH, Moore SJ, Turnpenny PD, Lloyd DJ, Dean JC. Rasalam AD, et al. Dev Med Child Neurol. 2005 Aug;47(8):551-5. doi: 10.1017/s0012162205001076. Dev Med Child Neurol. 2005. PMID: 16108456 Free article.
The aim of this study was to evaluate the clinical features and frequency of autistic disorder or Asperger syndrome (AS; according to Diagnostic and Statistical Manual of Mental Disorders, 4th edition [DSM-IV] criteria) in children exposed to anticonvulsant m …
The aim of this study was to evaluate the clinical features and frequency of autistic disorder or Asperger syndrome (AS; accor …
Fetal anticonvulsant syndrome and mutation in the maternal MTHFR gene.
Dean JC, Moore SJ, Osborne A, Howe J, Turnpenny PD. Dean JC, et al. Clin Genet. 1999 Sep;56(3):216-20. doi: 10.1034/j.1399-0004.1999.560306.x. Clin Genet. 1999. PMID: 10563481
We investigated the common 677 C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in samples from 57 patients and their parents and 152 controls to determine its contribution to the risk of fetal anticonvulsant syndrome. The 677 C>T mu …
We investigated the common 677 C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene in samples from 57 patients and their …
Intellectual functioning in clinically confirmed fetal valproate syndrome.
Bromley RL, Baker GA, Clayton-Smith J, Wood AG. Bromley RL, et al. Neurotoxicol Teratol. 2019 Jan-Feb;71:16-21. doi: 10.1016/j.ntt.2018.11.003. Epub 2018 Nov 16. Neurotoxicol Teratol. 2019. PMID: 30453023
BACKGROUND: An increased risk of impaired intelligence (IQ) has been documented in valproate-exposed children, but investigations have not previously focused on those with a clinical diagnosis of Fetal Valproate Syndrome (FVS). METHODS: This cross sectional o …
BACKGROUND: An increased risk of impaired intelligence (IQ) has been documented in valproate-exposed children, but investigations have not p …
Ophthalmic findings in fetal anticonvulsant syndrome(s).
Glover SJ, Quinn AG, Barter P, Hart J, Moore SJ, Dean JC, Turnpenny PD. Glover SJ, et al. Ophthalmology. 2002 May;109(5):942-7. doi: 10.1016/s0161-6420(02)00959-4. Ophthalmology. 2002. PMID: 11986102
PURPOSE: To report the prevalence of ocular abnormalities in a group of children diagnosed with fetal anticonvulsant (FAC) syndrome(s). DESIGN: Retrospective, observational, noncomparative case series. ...CONCLUSIONS: We conclude that (1) abnormal ophthalmic …
PURPOSE: To report the prevalence of ocular abnormalities in a group of children diagnosed with fetal anticonvulsant (FAC) …
Pregnancy in the woman with epilepsy: maternal and fetal outcomes.
Pennell PB. Pennell PB. Semin Neurol. 2002 Sep;22(3):299-308. doi: 10.1055/s-2002-36649. Semin Neurol. 2002. PMID: 12528055 Review.
Periodic monitoring of total and free AED levels is recommended. The "fetal anticonvulsant syndrome" has been described with all of the AEDs and includes major malformations, minor anomalies, microcephaly, cognitive impairment, intrauterine growth retardation …
Periodic monitoring of total and free AED levels is recommended. The "fetal anticonvulsant syndrome" has been described …
Exome sequencing in patients with antiepileptic drug exposure and complex phenotypes.
Jackson A, Ward H, Bromley RL, Deshpande C, Vasudevan P, Scurr I, Dean J, Shannon N, Berg J, Holder S, Baralle D, Clayton-Smith J; DDD Study. Jackson A, et al. Arch Dis Child. 2020 Apr;105(4):384-389. doi: 10.1136/archdischild-2018-316547. Epub 2019 Sep 3. Arch Dis Child. 2020. PMID: 31481360
INTRODUCTION: Fetal anticonvulsant syndrome (FACS) describes the pattern of physical and developmental problems seen in those children exposed to certain antiepileptic drugs (AEDs) in utero. The diagnosis of FACS is a clinical one and so excluding alte …
INTRODUCTION: Fetal anticonvulsant syndrome (FACS) describes the pattern of physical and developmental problems seen in …
A clinical study of 57 children with fetal anticonvulsant syndromes.
Moore SJ, Turnpenny P, Quinn A, Glover S, Lloyd DJ, Montgomery T, Dean JC. Moore SJ, et al. J Med Genet. 2000 Jul;37(7):489-97. doi: 10.1136/jmg.37.7.489. J Med Genet. 2000. PMID: 10882750 Free PMC article.
To evaluate the pattern of abnormalities associated with prenatal anticonvulsant exposure further, we undertook a clinical study of 57 children with fetal anticonvulsant syndromes. METHODS: Fifty two children were ascertained through the Fetal
To evaluate the pattern of abnormalities associated with prenatal anticonvulsant exposure further, we undertook a clinical stu …
Dysmorphic features: an important clue to the diagnosis and severity of fetal anticonvulsant syndromes.
Kini U, Adab N, Vinten J, Fryer A, Clayton-Smith J; Liverpool and Manchester Neurodevelopmental Study Group. Kini U, et al. Arch Dis Child Fetal Neonatal Ed. 2006 Mar;91(2):F90-5. doi: 10.1136/adc.2004.067421. Epub 2005 Oct 20. Arch Dis Child Fetal Neonatal Ed. 2006. PMID: 16239295 Free PMC article.
Nearly half (45%) of unexposed children had some of the facial features associated with AED exposure, showing that many of these features may be seen as part of normal variation and that the diagnosis of the fetal anticonvulsant syndrome is difficult to make …
Nearly half (45%) of unexposed children had some of the facial features associated with AED exposure, showing that many of these features ma …
19 results