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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1980 1
1981 1
1982 3
1983 8
1984 9
1985 22
1986 40
1987 39
1988 53
1989 118
1990 111
1991 161
1992 229
1993 259
1994 199
1995 297
1996 308
1997 301
1998 368
1999 447
2000 475
2001 504
2002 496
2003 473
2004 524
2005 588
2006 646
2007 606
2008 588
2009 575
2010 646
2011 674
2012 690
2013 644
2014 637
2015 671
2016 640
2017 671
2018 535
2019 246
2020 4
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13,290 results
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Page 1
Recent updates of fluoroquinolones as antibacterial agents.
Ezelarab HAA, et al. Arch Pharm (Weinheim) 2018 - Review. PMID 30048015
Conjugation of fluoroquinolones with substitutions such as 1,2,4-triazoles, alkyl oximes, flavonoids, aryl furans, benzofuroxans, metronidazoles or even other antibiotics such as neomycin-B produced derivatives that have a superior and wider spectrum of activity and better resistance than the classical fluoroquinolone agents. Addition of a hydroxamic acid moiety to fluoroquinolones also increased the activity against Proteus mirabilis, which represents one of the most resistant strains of bacteria in urinary tract infections. ...
Conjugation of fluoroquinolones with substitutions such as 1,2,4-triazoles, alkyl oximes, flavonoids, aryl furans, benzofuroxans, met …
Fluoroquinolones and the aorta.
Juurlink DN. BMJ 2018. PMID 29519782
Fluoroquinolones versus trimethoprim-sulfamethoxazole for the treatment of Stenotrophomonas maltophilia infections: a systematic review and meta-analysis.
Ko JH, et al. Clin Microbiol Infect 2019. PMID 30448331
BACKGROUND: Fluoroquinolones are a popular alternative to trimethoprim-sulfamethoxazole for Stenotrophomonas maltophilia infections. ...CONCLUSIONS: Based on a meta-analysis of non-randomized studies, fluoroquinolones demonstrated comparable effects on mortality of S. maltophilia infection to trimethoprim-sulfamethoxazole, supporting the use of fluoroquinolones in clinical S. maltophilia infections. ...
BACKGROUND: Fluoroquinolones are a popular alternative to trimethoprim-sulfamethoxazole for Stenotrophomonas maltophilia infections. …
Treatment Options for Carbapenem- Resistant Gram-Negative Infections
Fritzenwanker M, et al. Dtsch Arztebl Int 2018 - Review. PMID 29914612 Free PMC article.
RESULTS: Multiresistant Gram-negative (MRGN) pathogens are classified in Germany according to their resistance to four different classes of antibiotics; fluoroquinolones, piperacillin, third-generation cephalosporins, and carbapenems. ...
RESULTS: Multiresistant Gram-negative (MRGN) pathogens are classified in Germany according to their resistance to four different classes of …
Oral Fluoroquinolone and the Risk of Aortic Dissection.
Lee CC, et al. J Am Coll Cardiol 2018. PMID 30213330 Free article.
Susceptible period analysis revealed that the use of fluoroquinolone within 60 days was associated with the highest risk of AA/AD. ...CONCLUSIONS: Exposure to fluoroquinolone was substantially associated with AA/AD. This risk was modified by the duration of fluoroquinolone use and the length of the hazard period....
Susceptible period analysis revealed that the use of fluoroquinolone within 60 days was associated with the highest risk of AA/AD. .. …
Fluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study.
Pasternak B, et al. BMJ 2018. PMID 29519881 Free PMC article.
OBJECTIVE: To investigate whether oral fluoroquinolone use is associated with an increased risk of aortic aneurysm or dissection. ...CONCLUSIONS: In a propensity score matched cohort, fluoroquinolone use was associated with an increased risk of aortic aneurysm or dissection. ...
OBJECTIVE: To investigate whether oral fluoroquinolone use is associated with an increased risk of aortic aneurysm or dissection. ... …
Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis
Collaborative Group for the Meta-Analysis of Individual Patient Data in MDR-TB treatment–2017 , et al. Lancet 2018 - Review. PMID 30215381 Free PMC article.
INTERPRETATION: Although inferences are limited by the observational nature of these data, treatment outcomes were significantly better with use of linezolid, later generation fluoroquinolones, bedaquiline, clofazimine, and carbapenems for treatment of multidrug-resistant tuberculosis. ...
INTERPRETATION: Although inferences are limited by the observational nature of these data, treatment outcomes were significantly better with …
Fluoroquinolones and the risk of aortopathy: A systematic review and meta-analysis.
Noman AT, et al. Int J Cardiol 2019. PMID 30309682
Primary outcome of interest was development of aortic aneurysm or dissection among fluoroquinolones users in comparison to non-users. ...CONCLUSION: Our findings indicate that current fluoroquinolone use was significantly associated with increased risk of aortic aneurysm and dissection. ...
Primary outcome of interest was development of aortic aneurysm or dissection among fluoroquinolones users in comparison to non-users. …
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