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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1951 2
1954 2
1955 2
1957 2
1958 1
1959 3
1960 9
1961 7
1962 12
1963 75
1964 170
1965 118
1966 98
1967 149
1968 181
1969 192
1970 247
1971 269
1972 283
1973 287
1974 323
1975 177
1976 121
1977 103
1978 86
1979 76
1980 76
1981 71
1982 75
1983 72
1984 62
1985 49
1986 52
1987 52
1988 56
1989 51
1990 56
1991 50
1992 74
1993 69
1994 72
1995 74
1996 83
1997 66
1998 77
1999 97
2000 96
2001 105
2002 87
2003 97
2004 119
2005 137
2006 126
2007 134
2008 143
2009 151
2010 149
2011 144
2012 160
2013 150
2014 180
2015 200
2016 197
2017 173
2018 145
2019 90
2020 0
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6,818 results
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Page 1
Advancing Freund's and AddaVax Adjuvant Regimens Using CpG Oligodeoxynucleotides.
Hawksworth D. Monoclon Antib Immunodiagn Immunother 2018. PMID 30281392
Adjuvant can play an important role in vaccine formulation by aiding in the development of a robust immune response. In our hybridoma development work, we typically use both Freund's and AddaVax™ adjuvant regimens for mouse immunizations. ...To that end, we evaluated the use of CpG oligodeoxynucleotides (CpG-DNA), a B cell stimulant, in our adjuvant regimens. Mice were immunized using our standard Freund's protocol (Adjulite Complete Freund's Adjuvant for the primary immunization followed by Adjulite Incomplete Freund's Adjuvant (AIFA) for all additional immunizations) or a test protocol using AIFA supplemented with CpG-DNA for all immunizations. ...
Adjuvant can play an important role in vaccine formulation by aiding in the development of a robust immune response. In our hybridoma
Antiarthritic Activity of Diallyl Disulfide against Freund's Adjuvant-Induced Arthritic Rat Model.
Chen Y, et al. J Environ Pathol Toxicol Oncol 2018. PMID 30806236
The aim of the present study was to evaluate the antiarthritic activity of DADS in rats with arthritis induced using complete Freund's adjuvant (CFA). ...
The aim of the present study was to evaluate the antiarthritic activity of DADS in rats with arthritis induced using complete Freund' …
Mannosylated T/Tn with Freund's adjuvant induces cellular immunity.
Son HY, et al. Int J Immunopathol Pharmacol 2018. PMID 29251002 Free PMC article.
Immunization was performed using: T/Tn only, T/Tn mixed with Freund's adjuvant (T/Tn + FA), keyhole limpet hemocyanin (KLH)-conjugated T/Tn mixed with FA (KLH-T/Tn + FA), and oxidized mannan-conjugated T/Tn mixed with FA (ox-M-T/Tn + FA). ...
Immunization was performed using: T/Tn only, T/Tn mixed with Freund's adjuvant (T/Tn + FA), keyhole limpet hemocyanin ( …
CoVaccine HT™ adjuvant is superior to Freund's adjuvants in eliciting antibodies against the endogenous alarmin HMGB1.
Lakhan N, et al. J Immunol Methods 2016. PMID 27693642
Sheep were immunised with HMGB1 protein in CoVaccine HT™ or Freund's adjuvants, with injection site reactions and antibody titres periodically assessed. ...These studies provide evidence that CoVaccine HT™ is superior to Freund's adjuvants for the production of antibodies to antigens with low immunogenicity and supports the use of this alternative adjuvant for clinical and experimental use antibodies....
Sheep were immunised with HMGB1 protein in CoVaccine HT™ or Freund's adjuvants, with injection site reactions and antibody tit …
Role of Sinomenine on Complete Freund's Adjuvant-Induced Arthritis in Rats.
Lan Z, et al. IUBMB Life 2016. PMID 27079983 Free article.
The investigation was undertaken to evaluate the effect of sinomenine (Sin) on experimental adjuvant arthritis rats stimulated by Freund's complete adjuvant and explore the corresponding potential molecular mechanism. ...
The investigation was undertaken to evaluate the effect of sinomenine (Sin) on experimental adjuvant arthritis rats stimulated by …
Urinary metabolomics of complete Freund's adjuvant-induced hyperalgesia in rats.
Liu Y, et al. Biomed Chromatogr 2017. PMID 28058725
An emulsion containing 500 μg of Complete Freund's adjuvant (CFA) was used to induce hyperalgesia. Urine samples were collected prior to the injection of CFA and on post-injection days 1, 3 and 7. ...
An emulsion containing 500 μg of Complete Freund's adjuvant (CFA) was used to induce hyperalgesia. Urine samples were c …
Venlafaxine alleviates complete Freund's adjuvant-induced arthritis in rats: Modulation of STAT-3/IL-17/RANKL axis.
Kamel KM, et al. Life Sci 2019. PMID 30928406
METHODS: Arthritis was induced by injecting complete Freund's adjuvant (CFA, 0.1 ml, s.c.). One day thereafter, VFX (50 mg/kg, p.o.) was given for 21 days. ...
METHODS: Arthritis was induced by injecting complete Freund's adjuvant (CFA, 0.1 ml, s.c.). One day thereafter, VFX (50 …
Contribution of platelet P2Y(12) receptors to chronic Complete Freund's adjuvant-induced inflammatory pain.
Bekő K, et al. J Thromb Haemost 2017. PMID 28345287 Free article.
Complete Freund's Adjuvant (CFA)-induced chronic inflammatory pain model was used in mice. Gene deficiency and antagonists of P2Y(12) receptors attenuate hyperalgesia and local inflammation. ...Methods Complete Freund's adjuvant (CFA)-induced chronic inflammatory pain was induced in wild-type and P2ry12 gene-deficient (P2ry12(-/-) ) mice, and the potent, direct-acting and reversible P2Y(12) receptor antagonists PSB-0739 and cangrelor were used. ...
Complete Freund's Adjuvant (CFA)-induced chronic inflammatory pain model was used in mice. Gene deficiency and antagoni …
Complete Freund's adjuvant induces experimental autoimmune myocarditis by enhancing IL-6 production during initiation of the immune response.
Fontes JA, et al. Immun Inflamm Dis 2017. PMID 28474508 Free PMC article.
INTRODUCTION: Complete Freund's Adjuvant (CFA) emulsified with an antigen is a widely used method to induce autoimmune disease in animal models, yet the contribution of CFA to the immune response is not well understood. We compared the effectiveness of CFA with Incomplete Freund's Adjuvant (IFA) or TiterMax Gold Adjuvant (TMax) in experimental autoimmune myocarditis (EAM) in male mice. ...
INTRODUCTION: Complete Freund's Adjuvant (CFA) emulsified with an antigen is a widely used method to induce autoimmune …
Probucol Ameliorates Complete Freund's Adjuvant-Induced Hyperalgesia by Targeting Peripheral and Spinal Cord Inflammation.
Zucoloto AZ, et al. Inflammation 2019. PMID 31011926
The effect of the lipid-lowering agent probucol in inflammatory hyperalgesia and leukocyte recruitment was evaluated in a model of subacute inflammation by Complete Freund's adjuvant (CFA). ...
The effect of the lipid-lowering agent probucol in inflammatory hyperalgesia and leukocyte recruitment was evaluated in a model of subacute …
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