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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1979 4
1981 2
1982 3
1983 8
1984 11
1985 18
1986 15
1987 24
1988 13
1989 15
1990 34
1991 25
1992 19
1993 27
1994 31
1995 28
1996 23
1997 25
1998 18
1999 21
2000 23
2001 28
2002 24
2003 24
2004 24
2005 15
2006 21
2007 22
2008 23
2009 15
2010 19
2011 21
2012 22
2013 20
2014 24
2015 21
2016 20
2017 26
2018 23
2019 14
2020 0
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756 results
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Page 1
The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic Francisella.
Ziveri J, et al. Nat Commun 2017. PMID 29021545 Free PMC article.
Here, we address the role of fructose-bisphosphate aldolase in the bacterial pathogen Francisella novicida. We demonstrate that fructose-bisphosphate aldolase is important for bacterial multiplication in macrophages in the presence of gluconeogenic substrates. ...We propose a model in which fructose-bisphosphate aldolase participates in the control of host redox homeostasis and the inflammatory immune response.The enzyme fructose-bisphosphate aldolase (FBA) plays central roles in glycolysis and gluconeogenesis. ...
Here, we address the role of fructose-bisphosphate aldolase in the bacterial pathogen Francisella novicida. We demonstr …
Fructose-1,6-bisphosphate aldolase encoded by a core gene of Mycoplasma hyopneumoniae contributes to host cell adhesion.
Yu Y, et al. Vet Res 2018. PMID 30454073 Free PMC article.
The most differentially abundant of the seven, fructose-1,6-bisphosphate aldolase (FBA), was successfully cloned, expressed and purified. ...
The most differentially abundant of the seven, fructose-1,6-bisphosphate aldolase (FBA), was successfully cloned, expre …
Pcal_0111, a highly thermostable bifunctional fructose-1,6-bisphosphate aldolase/phosphatase from Pyrobaculum calidifontis.
Aziz I, et al. Extremophiles 2017. PMID 28299451
Pyrobaculum calidifontis genome harbors an open reading frame Pcal_0111 annotated as fructose bisphosphate aldolase. Although the gene is annotated as fructose bisphosphate aldolase, it exhibits a high homology with previously reported fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus. ...High thermostability and inhibition by ATP make Pcal_0111 a unique fructose 1,6-bisphosphatase/aldolase....
Pyrobaculum calidifontis genome harbors an open reading frame Pcal_0111 annotated as fructose bisphosphate aldolase. Al …
Hereditary fructose intolerance.
Ali M, et al. J Med Genet 1998 - Review. PMID 9610797 Free PMC article.
Hereditary fructose intolerance (HFI, OMIM 22960), caused by catalytic deficiency of aldolase B (fructose-1,6-bisphosphate aldolase, EC 4.1.2.13), is a recessively inherited condition in which affected homozygotes develop hypoglycaemic and severe abdominal symptoms after taking foods containing fructose and cognate sugars. Continued ingestion of noxious sugars leads to hepatic and renal injury and growth retardation; parenteral administration of fructose or sorbitol may be fatal. ...
Hereditary fructose intolerance (HFI, OMIM 22960), caused by catalytic deficiency of aldolase B (fructose-1,6-bispho
Characterization and localization of Opisthorchis viverrini fructose-1,6-bisphosphate aldolase.
Prompipak J, et al. Parasitol Int 2017. PMID 27265876
In this study, an important enzyme in the Ov glycolytic pathway, fructose-1,6-bisphosphate aldolase (FBPA), that had been obtained from a previous study was characterized and immunolocalized. ...
In this study, an important enzyme in the Ov glycolytic pathway, fructose-1,6-bisphosphate aldolase (FBPA), that had be …
Fructose-1,6-bisphosphate aldolase of Neisseria meningitidis binds human plasminogen via its C-terminal lysine residue.
Shams F, et al. Microbiologyopen 2016. PMID 26732512 Free PMC article.
Fructose-1,6-bisphosphate aldolase (FBA) was previously shown to be surface-exposed in meningococci and involved in adhesion to host cells. In this study, FBA was shown to be present on the surface of both pathogenic and commensal neisseriae, and surface localization and anchoring was demonstrated to be independent of aldolase activity. ...
Fructose-1,6-bisphosphate aldolase (FBA) was previously shown to be surface-exposed in meningococci and involved in adh
Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis.
Kawai K, et al. Int J Oncol 2017. PMID 28000858
To better understand the molecular mechanisms of cancer malignancy, we investigated the expression of fructose-bisphosphate aldolase A (ALDOA) and its relationship with cancer metabolism. ...
To better understand the molecular mechanisms of cancer malignancy, we investigated the expression of fructose-bisphosphate
The biochemical basis of hereditary fructose intolerance.
Bouteldja N and Timson DJ. J Inherit Metab Dis 2010 - Review. PMID 20162364
Hereditary fructose intolerance is a rare, but potentially lethal, inherited disorder of fructose metabolism, caused by mutation of the aldolase B gene. ...This review gives a general overview of the features of hereditary fructose intolerance, then concentrates on the biochemistry of the AP variant (Ala149Pro variant of aldolase B) and molecular pathological consequences of mutation of the aldolase B gene....
Hereditary fructose intolerance is a rare, but potentially lethal, inherited disorder of fructose metabolism, caused by mutati …
The secreted fructose 1,6-bisphosphate aldolase as a broad spectrum vaccine candidate against pathogenic bacteria in aquaculture.
Sun Z, et al. Fish Shellfish Immunol 2015. PMID 26256425
In this study, fructose 1,6-bisphosphate aldolase (FBA), a conserved enzyme in the glycolytic pathway, was demonstrated to be located in the non-cytoplasmic components of five aquatic pathogenic bacteria and exhibited remarkable protection and cross-protection against these pathogens in turbot and zebrafish. ...
In this study, fructose 1,6-bisphosphate aldolase (FBA), a conserved enzyme in the glycolytic pathway, was demonstrated …
Crystallographic snapshots of active site metal shift in E. coli fructose 1,6-bisphosphate aldolase.
Tran HT, et al. BMB Rep 2016. PMID 27733232 Free PMC article.
Fructose 1,6-bisphosphate aldolase (FBA) is important for both glycolysis and gluconeogenesis in life. Class II (zinc dependent) FBA is an attractive target for the development of antibiotics against protozoa, bacteria, and fungi, and is also widely used to produce various high-value stereoisomers in the chemical and pharmaceutical industry. ...
Fructose 1,6-bisphosphate aldolase (FBA) is important for both glycolysis and gluconeogenesis in life. Class II (zinc d
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