"GABA Modulators/chemical synthesis"[MAJR] - Search Results

Year	Number of Results
1998	1
2000	2
2003	1
2005	2
2006	2
2008	1
2009	1
2010	1
2013	1
2014	1
2015	1
2017	1
2020	2
2021	1
2024	0

1

Rational approaches for the design of various GABA modulators and their clinical progression.

Bhagat K, Singh JV, Pagare PP, Kumar N, Sharma A, Kaur G, Kinarivala N, Gandu S, Singh H, Sharma S, Bedi PMS. Bhagat K, et al. Mol Divers. 2021 Feb;25(1):551-601. doi: 10.1007/s11030-020-10068-4. Epub 2020 Mar 13. Mol Divers. 2021. PMID: 32170466 Free PMC article. Review.

2

Exploiting the Indole Scaffold to Design Compounds Binding to Different Pharmacological Targets.

Taliani S, Da Settimo F, Martini C, Laneri S, Novellino E, Greco G. Taliani S, et al. Molecules. 2020 May 16;25(10):2331. doi: 10.3390/molecules25102331. Molecules. 2020. PMID: 32429433 Free PMC article. Review.

3

Design, Synthesis, and Docking Study of Pyrimidine-Triazine Hybrids for GABA Estimation in Animal Epilepsy Models.

Sahu M, Siddiqui N, Naim MJ, Alam O, Yar MS, Sharma V, Wakode S. Sahu M, et al. Arch Pharm (Weinheim). 2017 Sep;350(9). doi: 10.1002/ardp.201700146. Epub 2017 Jul 31. Arch Pharm (Weinheim). 2017. PMID: 28758238

4

Total synthesis of valerenic acid, a potent GABAA receptor modulator.

Ramharter J, Mulzer J. Ramharter J, et al. Org Lett. 2009 Mar 5;11(5):1151-3. doi: 10.1021/ol9000137. Org Lett. 2009. PMID: 19178294

5

Conformationally constrained anesthetic steroids that modulate GABA(A) receptors.

Anderson A, Boyd AC, Clark JK, Fielding L, Gemmell DK, Hamilton NM, Maidment MS, May V, McGuire R, McPhail P, Sansbury FH, Sundaram H, Taylor R. Anderson A, et al. J Med Chem. 2000 Nov 2;43(22):4118-25. doi: 10.1021/jm000977e. J Med Chem. 2000. PMID: 11063608

6

GABAergic dysfunction in essential tremor: an 11C-flumazenil PET study.

Boecker H, Weindl A, Brooks DJ, Ceballos-Baumann AO, Liedtke C, Miederer M, Sprenger T, Wagner KJ, Miederer I. Boecker H, et al. J Nucl Med. 2010 Jul;51(7):1030-5. doi: 10.2967/jnumed.109.074120. Epub 2010 Jun 16. J Nucl Med. 2010. PMID: 20554735 Free article.

7

Neurosteroid analogues. 14. Alternative ring system scaffolds: GABA modulatory and anesthetic actions of cyclopenta[b]phenanthrenes and cyclopenta[b]anthracenes.

Scaglione JB, Jastrzebska I, Krishnan K, Li P, Akk G, Manion BD, Benz A, Taylor A, Rath NP, Evers AS, Zorumski CF, Mennerick S, Covey DF. Scaglione JB, et al. J Med Chem. 2008 Mar 13;51(5):1309-18. doi: 10.1021/jm701128r. Epub 2008 Feb 15. J Med Chem. 2008. PMID: 18275132

8

Novel 17beta-substituted conformationally constrained neurosteroids that modulate GABA A receptors.

Souli C, Avlonitis N, Calogeropoulou T, Tsotinis A, Maksay G, Bíró T, Politi A, Mavromoustakos T, Makriyannis A, Reis H, Papadopoulos M. Souli C, et al. J Med Chem. 2005 Aug 11;48(16):5203-14. doi: 10.1021/jm050271q. J Med Chem. 2005. PMID: 16078839

9

Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone.

Qian M, Krishnan K, Kudova E, Li P, Manion BD, Taylor A, Elias G, Akk G, Evers AS, Zorumski CF, Mennerick S, Covey DF. Qian M, et al. J Med Chem. 2014 Jan 9;57(1):171-90. doi: 10.1021/jm401577c. Epub 2013 Dec 24. J Med Chem. 2014. PMID: 24328079 Free PMC article.

10

Neurosteroid analogues. 11. Alternative ring system scaffolds: gamma-aminobutyric acid receptor modulation and anesthetic actions of benz[f]indenes.

Scaglione JB, Manion BD, Benz A, Taylor A, DeKoster GT, Rath NP, Evers AS, Zorumski CF, Mennerick S, Covey DF. Scaglione JB, et al. J Med Chem. 2006 Jul 27;49(15):4595-605. doi: 10.1021/jm0602920. J Med Chem. 2006. PMID: 16854065

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