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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 3
1947 1
1948 3
1949 2
1951 6
1952 7
1953 3
1954 7
1955 6
1956 8
1957 6
1958 12
1959 14
1960 20
1961 18
1962 16
1965 17
1966 36
1967 46
1968 65
1969 44
1970 56
1971 62
1972 70
1973 67
1974 105
1975 95
1976 75
1977 72
1978 84
1979 90
1980 74
1981 79
1982 85
1983 113
1984 110
1985 105
1986 110
1987 110
1988 103
1989 138
1990 155
1991 118
1992 130
1993 121
1994 86
1995 104
1996 88
1997 107
1998 77
1999 67
2000 89
2001 65
2002 64
2003 75
2004 73
2005 70
2006 67
2007 66
2008 52
2009 49
2010 49
2011 51
2012 60
2013 61
2014 50
2015 49
2016 47
2017 40
2018 28
2019 17
2020 1
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4,220 results
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Page 1
Functions of the Gallbladder.
Housset C, et al. Compr Physiol 2016 - Review. PMID 27347902
The gallbladder stores and concentrates bile between meals. Gallbladder motor function is regulated by bile acids via the membrane bile acid receptor, TGR5, and by neurohormonal signals linked to digestion, for example, cholecystokinin and FGF15/19 intestinal hormones, which trigger gallbladder emptying and refilling, respectively. ...Among subjects with gallstones, cholecystectomy remains a priority in those at risk of gallbladder cancer, while others could benefit from gallbladder-preserving strategies. © 2016 American Physiological Society. ...
The gallbladder stores and concentrates bile between meals. Gallbladder motor function is regulated by bile acids via the memb …
A model of gallbladder motility.
Żulpo M, et al. Comput Biol Med 2018. PMID 29306087
Impaired gallbladder motility leads to some clinical manifestations associated with its muscle contraction and/or the rate of filling with bile. ...We found that different gallbladder emptying patterns may result from differences in the amplitude of contraction of gallbladder muscles (e.g. for various meal composition), differences in the rate of bile inflow (e.g. for obese patients during filling), and differences in gallbladder muscle pulsations (e.g. for lean patients during early gallbladder emptying). ...
Impaired gallbladder motility leads to some clinical manifestations associated with its muscle contraction and/or the rate of filling …
Effect of a high-fat-high-cholesterol diet on gallbladder bile acid composition and gallbladder motility in dogs.
Kakimoto T, et al. Am J Vet Res 2017. PMID 29182389
Before and at the end of each feeding period, the concentrations of each of the gallbladder bile acids, cholecystokinin (CCK)-induced gallbladder motility, and bile acid metabolism-related hepatic gene expression were examined in all dogs. ...CONCLUSIONS AND CLINICAL RELEVANCE Feeding the HFCD and LFD for 2 weeks induced changes in gallbladder bile acid composition and gallbladder motility in dogs. ...
Before and at the end of each feeding period, the concentrations of each of the gallbladder bile acids, cholecystokinin (CCK)-induced …
Physiology and pathophysiology of gallbladder motility.
Tierney S, et al. Surg Clin North Am 1993 - Review. PMID 8248838
Most significant gallbladder disease is associated with gallbladder stasis. Gallbladder motility is controlled by a complex interplay of hormonal and neural factors. ...The ability to measure gallbladder motility clinically has also resulted in better diagnosis and treatment for patients with chronic acalculous cholecystitis....
Most significant gallbladder disease is associated with gallbladder stasis. Gallbladder motility is controlled by a com …
Measurement of the mechanical properties of the human gallbladder.
Karimi A, et al. J Med Eng Technol 2017. PMID 28849953
The gallbladder can subject to the mechanical deformation/loading as a result of the cholecystitis, cholesterolosis of the gallbladder, etc. However, so far the mechanical properties of the human gallbladder have not been measured. This study was aimed at conducting an experimental study to measure the mechanical properties of the human gallbladder under the axial and transversal tensile loadings. ...
The gallbladder can subject to the mechanical deformation/loading as a result of the cholecystitis, cholesterolosis of the gallbla
Occurrence of the specific long spike burst pattern in the ovine proximal gallbladder as an indication of myoelectric regional variability.
Romański KW and Nicpoń J. Onderstepoort J Vet Res 2018. PMID 29943583 Free PMC article.
The myoelectrical activity of the ovine gallbladder has not been fully recognised. Five rams were fitted with six small intestinal and three gallbladder electrodes and a strain gauge force transducer was mounted near the gallbladder fundic electrode. ...Similar events were recorded in the gallbladder corpus, but the specific pattern was shorter and irregular. In the gallbladder fundus, mostly irregular short spike bursts were recorded. ...
The myoelectrical activity of the ovine gallbladder has not been fully recognised. Five rams were fitted with six small intestinal an …
[Effects of glucagon-like peptides on gallbladder motility].
Gether IM, et al. Ugeskr Laeger 2018. PMID 30547877 Danish.
As cases of gallbladder-related adverse events have been reported in patients treated with glucagon-like peptide (GLP)-1 receptor agonists and GLP-2 receptor agonists, studies have investigated the effects of these hormones on the enterohepatic circulation of bile acids and gallbladder motility. Results suggest, that bile acids and GLP-2 counteract postprandial cholecystokinin-mediated gallbladder contraction, while GLP-1 may delay gallbladder refilling. ...
As cases of gallbladder-related adverse events have been reported in patients treated with glucagon-like peptide (GLP)-1 receptor ago …
The role of the gallbladder in humans.
Turumin JL, et al. Rev Gastroenterol Mex 2013 - Review. PMID 23683886 Free article.
The basic function of the gallbladder in humans is one of protection. The accumulation of the primary bile acids (cholic acid and chenodeoxycholic acid) in the gallbladder reduces the formation of the secondary bile acids (deoxycholic acid and lithocholic acid), thus diminishing their concentration in the so-called gallbladder-independent enterohepatic circulation and protecting the liver, the stomach mucosa, the gallbladder, and the colon from their toxic hydrophobic effects. ...Because the gallbladder contracts 5-20 min after food is in the stomach and the "gastric chyme" moves from the stomach to the duodenum 1-3 h later, the function of the gallbladder bile in digestion may be insignificant. ...
The basic function of the gallbladder in humans is one of protection. The accumulation of the primary bile acids (cholic acid and che …
A Gallbladder-Based Enterohepatic Circulation Model for Pharmacokinetic Studies.
Okour M and Brundage RC. Eur J Drug Metab Pharmacokinet 2019. PMID 30488336
Regardless, the addition of a gallbladder to the model does not fully depict the physiology of EHC. A more physiological gallbladder-based EHC model is needed. This model should take into account a physiological representation of the bile secretion, gallbladder filling and emptying, the duration of gallbladder emptying, and irregular mealtimes. ...
Regardless, the addition of a gallbladder to the model does not fully depict the physiology of EHC. A more physiological ga
Glucagon-like peptide-2 promotes gallbladder refilling via a TGR5-independent, GLP-2R-dependent pathway.
Yusta B, et al. Mol Metab 2017. PMID 28580281 Free PMC article.
Unexpectedly, reports of gallbladder disease have been associated with the use of both GLP-1R and GLP-2R agonists and after bariatric surgery, although the mechanisms remain unknown. METHODS: We investigated whether GLP-1 or GLP-2 acutely controls gallbladder (GB) volume and whether GLP-2 regulates GB muscle activity in mice. ...
Unexpectedly, reports of gallbladder disease have been associated with the use of both GLP-1R and GLP-2R agonists and after bariatric …
4,220 results
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