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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 2
1946 3
1947 3
1948 3
1949 2
1950 1
1951 11
1952 33
1953 24
1954 21
1955 30
1956 61
1957 54
1958 73
1959 71
1960 73
1961 66
1962 35
1963 3
1964 2
1965 60
1966 174
1967 221
1968 264
1969 250
1970 207
1971 263
1972 288
1973 265
1974 270
1975 288
1976 325
1977 337
1978 299
1979 265
1980 319
1981 295
1982 339
1983 343
1984 368
1985 428
1986 398
1987 412
1988 475
1989 457
1990 493
1991 475
1992 568
1993 583
1994 559
1995 641
1996 640
1997 706
1998 914
1999 826
2000 817
2001 909
2002 1031
2003 1130
2004 1161
2005 1374
2006 1538
2007 1630
2008 1734
2009 1769
2010 1923
2011 2086
2012 2477
2013 2477
2014 2661
2015 2515
2016 2435
2017 2284
2018 2245
2019 1084
2020 17
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46,209 results
Results by year
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Page 1
Endocannabinoid-related compounds in gastrointestinal diseases.
Pesce M, et al. J Cell Mol Med 2018 - Review. PMID 28990365 Free PMC article.
The endocannabinoid system (ECS) is an endogenous signalling pathway involved in the control of several gastrointestinal (GI) functions at both peripheral and central levels. ...This review summarizes the possible mechanisms linking the ECS to GI disorders and describes the most recent advances in the manipulation of the ECS in the treatment of GI diseases....
The endocannabinoid system (ECS) is an endogenous signalling pathway involved in the control of several gastrointestinal (GI) functio …
Intestinal fibrosis
Lenti MV and Di Sabatino A. Mol Aspects Med 2019 - Review. PMID 30385174
Extensive tissue fibrosis is the end-stage process of a number of chronic conditions affecting the gastrointestinal tract, including inflammatory bowel disease (Crohn's disease, ulcerative colitis), ulcerative jejunoileitis, and radiation enteritis. ...
Extensive tissue fibrosis is the end-stage process of a number of chronic conditions affecting the gastrointestinal tract, including …
All disease begins in the gut: Influence of gastrointestinal disorders and surgery on oral drug performance.
Hatton GB, et al. Int J Pharm 2018 - Review. PMID 29969711
However, the effects of the various gastrointestinal diseases, infections, co-morbidities and the impact of gastrointestinal surgery on the pharmacokinetic and pharmacodynamic behaviour of drugs have been largely overlooked. ...Here, we revisit and re-evaluate the influence of a portfolio of gastrointestinal diseases and surgical effects on the functionality of the gastrointestinal tract, their implications for drug delivery and attempt to uncover significant links for clinical practice....
However, the effects of the various gastrointestinal diseases, infections, co-morbidities and the impact of gastrointestina
Melatonin's role as a co-adjuvant treatment in colonic diseases: A review.
Esteban-Zubero E, et al. Life Sci 2017 - Review. PMID 27919824
Melatonin has been studied as a co-adjuvant treatment in several gastrointestinal diseases including irritable bowel syndrome (IBS), constipation-predominant IBS (IBS-C), diarrhea-predominant IBS (IBS-D), Crohn's disease, ulcerative colitis, and necrotizing enterocolitis. The purpose of this review is to provide information regarding the potential benefits of melatonin as a co-adjuvant treatment in gastrointestinal diseases, especially IBS, Crohn's disease, ulcerative colitis, and necrotizing enterocolitis....
Melatonin has been studied as a co-adjuvant treatment in several gastrointestinal diseases including irritable bowel syndrome …
Wnt signaling in intestinal inflammation
Moparthi L and Koch S. Differentiation 2019 - Review. PMID 30718056 Free article.
Chronic inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are a major health burden worldwide. Numerous conserved signaling pathways control tissue injury and repair during colitis, but owing to the complexity of the inflammatory process, their individual contribution remains poorly understood. ...
Chronic inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are a major health burden worldwide. Numerous …
Control and dysregulation of redox signalling in the gastrointestinal tract.
Campbell EL and Colgan SP. Nat Rev Gastroenterol Hepatol 2019 - Review. PMID 30443019
Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to protect compromised mucosae from microbial infection through the generation of reactive oxygen species. ...This Review will address both the spectrum and intensity of redox activity pertaining to host-immune and host-microbiota crosstalk during homeostasis and disease processes in the gastrointestinal tract....
Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent microbicidal mechanisms can be used by infilt …
46,209 results
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