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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 2
1989 12
1990 27
1991 41
1992 25
1993 23
1994 27
1995 27
1996 17
1997 18
1998 23
1999 24
2000 25
2001 28
2002 35
2003 33
2004 40
2005 29
2006 34
2007 42
2008 49
2009 39
2010 37
2011 43
2012 35
2013 35
2014 19
2015 31
2016 24
2017 26
2018 26
2019 15
2020 0
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839 results
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Page 1
Utility of animal gastrointestinal motility and transit models in functional gastrointestinal disorders.
Al-Saffar A, et al. Best Pract Res Clin Gastroenterol 2019 - Review. PMID 31594654
Alteration in the gastrointestinal (GI) motility and transit comprises an important component of the functional gastrointestinal disorders (FGID). Available animal GI motility and transit models are to study symptoms (delayed gastric emptying, constipation, diarrhea) rather than biological markers to develop an effective treatment that targets the underlying mechanism of altered GI motility in patients. ...
Alteration in the gastrointestinal (GI) motility and transit comprises an important component of the functional gastrointes
A non-invasive method to evaluate gastrointestinal transit behavior in rat.
Bove GM. J Pharmacol Toxicol Methods 2015. PMID 25913851 Free PMC article.
INTRODUCTION: Many factors alter gastrointestinal transit. Animal models are useful for preclinical studies of gastrointestinal transit, but terminal methods do not allow later study, and stressful assessment methods will likely alter the transit of the animal. ...After establishing baseline transit times and hourly fecal pellet discharge, rats were given buprenorphine, known to alter gastrointestinal transit. ...
INTRODUCTION: Many factors alter gastrointestinal transit. Animal models are useful for preclinical studies of gastrointest
How does dietary particle size affect carnivore gastrointestinal transit: A dog model.
De Cuyper A, et al. J Anim Physiol Anim Nutr (Berl) 2018 - Clinical Trial. PMID 29030884
The effect of dietary particle size on gastrointestinal transit in carnivores has not been studied and might offer more insight into their digestive physiology. ...Dietary particle size did not affect gastric emptying time (GRT), small bowel transit time (SBTT), colonic transit time (CTT) and total transit time (aTTT) of the capsule (p > .05). ...
The effect of dietary particle size on gastrointestinal transit in carnivores has not been studied and might offer more insigh …
Gastrointestinal Motility, Part 1: Esophageal Transit and Gastric Emptying.
Maurer AH. J Nucl Med 2015 - Review. PMID 26025963 Free article.
Although not as well standardized as gastric emptying (GE) scintigraphy, esophageal transit scintigraphy, if performed in a comprehensive manner including both quantitative and qualitative analysis of single- and multiple-swallow studies, is clinically useful when expertise in esophageal manometry is not available or not tolerated and when esophageal manometry or barium videofluoroscopy results are equivocal or nondiagnostic. ...Both solid and liquid GE studies play an important role in assessing patients with upper gastrointestinal symptoms. Because measurement of simple total GE is often not sufficient to explain patient symptoms, there is a need to expand the analysis of GE scintigraphy to include the separate roles of the fundus and antrum and to include the complex interactions the stomach has with other organ systems....
Although not as well standardized as gastric emptying (GE) scintigraphy, esophageal transit scintigraphy, if performed in a comprehen …
Evaluation of gastrointestinal transit after infection with different loads of Strongyloides venezuelensis in rats.
Anjos-Ramos L, et al. Acta Trop 2016. PMID 26739657 Free article.
The aim was to correlate the gastrointestinal transit profile in rats, evaluated by a biomagnetic technique, in response to infection with different loads of Strongyloides venezuelensis. ...Our approach could be very helpful to evaluate gastrointestinal motor abnormalities in vivo after parasite infection. Despite parasitological data progressively decreased after 15 dpi, small intestinal transit worse over time and according to burden....
The aim was to correlate the gastrointestinal transit profile in rats, evaluated by a biomagnetic technique, in response to in …
Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice.
Kashyap PC, et al. Gastroenterology 2013. PMID 23380084 Free PMC article.
In addition to the direct influence that diet exerts on microbes, changes in microbiota composition and function can alter host functions such as gastrointestinal (GI) transit time, which in turn can further affect the microbiota. ...However, altered transit in mice fed a diet of fermentable fructooligosaccharide indicates that diet can change gut microbial function, which can affect GI transit. ...
In addition to the direct influence that diet exerts on microbes, changes in microbiota composition and function can alter host functions su …
Measurement of gastrointestinal transit.
Lin HC, et al. Dig Dis Sci 2005 - Review. PMID 15986844
An abnormality in transit is commonly considered to account for unexplained gastrointestinal (GI) symptoms. Since the symptoms of delayed transit overlap with those of accelerated transit, direct measurement of GI transit is needed to establish an accurate diagnosis. ...This review describes the most commonly used methods for the measurement of GI transit including the gastric emptying test for some dyspeptic symptoms, small bowel transit test for dyspeptic symptoms and diarrhea, colonic transit test for constipation, and factors that influence the result of these studies. ...
An abnormality in transit is commonly considered to account for unexplained gastrointestinal (GI) symptoms. Since the symptoms …
More movement with evaluating colonic transit in humans.
Bharucha AE, et al. Neurogastroenterol Motil 2019 - Review. PMID 30681255 Free PMC article.
Indeed, colonic transit accounts for a major part of the mouth-to-anus transit time. Colonic transit assessments are useful for understanding the pathophysiology of disease, the pharmacodynamic effects of new medications and to diagnose slow transit constipation. ...The next challenge is to harness different techniques to evaluate the relationships between colonic pressures and transit or, even better, the trifecta of colonic contractions, pressure events, and transit....
Indeed, colonic transit accounts for a major part of the mouth-to-anus transit time. Colonic transit assessments are us …
Disturbances of gastrointestinal transit and autonomic functions in postural orthostatic tachycardia syndrome.
Loavenbruck A, et al. Neurogastroenterol Motil 2015. PMID 25483980 Free PMC article.
BACKGROUND: Gastrointestinal symptoms are common in the postural orthostatic tachycardia syndrome (POTS). However, few studies have evaluated gastrointestinal transit in POTS. Our primary objectives were to evaluate gastrointestinal emptying and the relationship with autonomic dysfunctions in POTS. METHODS: We reviewed the complete medical records of all patients aged 18 years and older with POTS diagnosed by a standardized autonomic reflex screen who also had a scintigraphic assessment of gastrointestinal transit at Mayo Clinic Rochester between 1998 and 2012. ...
BACKGROUND: Gastrointestinal symptoms are common in the postural orthostatic tachycardia syndrome (POTS). However, few studies have e …
Regional gastrointestinal transit and pH studied in 215 healthy volunteers using the wireless motility capsule: influence of age, gender, study country and testing protocol.
Wang YT, et al. Aliment Pharmacol Ther 2015 - Clinical Trial. PMID 26223837 Free article.
BACKGROUND: The wireless motility capsule (WMC) offers the ability to investigate luminal gastrointestinal (GI) physiology in a minimally invasive manner. ...RESULTS: For GI transit times, testing protocol was associated with differences in gastric emptying time (GET; shorter with protocol 2 (motility capsule ingested immediately after meal) vs. protocol 1 (motility capsule immediately before): median difference: 52 min, P = 0.0063) and colonic transit time (CTT; longer with protocol 2: median 140 min, P = 0.0189), but had no overall effect on whole gut transit time. ...
BACKGROUND: The wireless motility capsule (WMC) offers the ability to investigate luminal gastrointestinal (GI) physiology in …
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