Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1965 2
1966 24
1967 59
1968 52
1969 78
1970 131
1971 94
1972 197
1973 295
1974 325
1975 300
1976 277
1977 291
1978 340
1979 324
1980 355
1981 336
1982 350
1983 468
1984 488
1985 672
1986 674
1987 863
1988 910
1989 1191
1990 1379
1991 1411
1992 1743
1993 1885
1994 2127
1995 2369
1996 2526
1997 2738
1998 2916
1999 3233
2000 3684
2001 3733
2002 4309
2003 4564
2004 4856
2005 5515
2006 6277
2007 7663
2008 8408
2009 8187
2010 8964
2011 9966
2012 11100
2013 11240
2014 10818
2015 10897
2016 11214
2017 10941
2018 10603
2019 5469
2020 121
Text availability
Article attribute
Article type
Publication date

Search Results

169,395 results
Results by year
Filters applied: . Clear all
Page 1
Gene expression regulation by retinoic acid.
Balmer JE and Blomhoff R. J Lipid Res 2002 - Review. PMID 12401878 Free article.
However, our understanding of the genetic role of retinoids will be enhanced if such a distinction can be made for each regulated gene. ...Data on another 267 targets are not evocative of direct or indirect regulation either way, although control by retinoic acid through some mechanism is clear (Category 1). ...
However, our understanding of the genetic role of retinoids will be enhanced if such a distinction can be made for each regulated gene
The integrated stress response
Pakos-Zebrucka K, et al. EMBO Rep 2016 - Review. PMID 27629041 Free PMC article.
The gene expression program activated by the ISR optimizes the cellular response to stress and is dependent on the cellular context, as well as on the nature and intensity of the stress stimuli. ...
The gene expression program activated by the ISR optimizes the cellular response to stress and is dependent on the cellular co …
Vitamin A and the epigenome
Bar-El Dadon S and Reifen R. Crit Rev Food Sci Nutr 2017 - Review. PMID 26565606
The epigenetic phenomena refer to heritable changes in gene expression other than those in the DNA sequence, such as DNA methylation and histone modifications. ...This influence is termed nutritional epigenetics, and one prominent example is the regulation of gene transcription by vitamin A through interaction to its nuclear receptor. ...
The epigenetic phenomena refer to heritable changes in gene expression other than those in the DNA sequence, such as DNA methy …
Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease.
Bailey EL, et al. Clin Sci (Lond) 2018. PMID 29632138 Free PMC article.
Results: We observed differences in gene and protein expression affecting the acute phase pathway and oxidative stress (ALB, AMBP, APOH, AHSG and LOC100129193, up-regulated in salt-loaded WKY versus WKY, >2-fold), active microglia (increased Iba-1 protein expression in salt-loaded SHRSP versus salt-loaded WKY, p<0.05), vascular structure (ACTB and CTNNB, up-regulated in salt-loaded SHRSP versus SHRSP, >3-fold; CLDN-11, VEGF and VGF down-regulated >2-fold in salt-loaded SHRSP versus SHRSP) and myelin integrity (MBP down-regulated in salt loaded WKY rats versus WKY, >2.5-fold). ...CONCLUSION: Salt exposure induced changes in gene and protein expression in an experimental model of SVD and its parent rat strain in multiple pathways involving components of the glio-vascular unit. ...
Results: We observed differences in gene and protein expression affecting the acute phase pathway and oxidative stress (ALB, A …
Molecular Mechanisms Underlying the Link between Diet and DNA Methylation
Kadayifci FZ, et al. Int J Mol Sci 2018 - Review. PMID 30558203 Free PMC article.
DNA methylation is a vital modification process in the control of genetic information, which contributes to the epigenetics by regulating gene expression without changing the DNA sequence. Abnormal DNA methylation-both hypomethylation and hypermethylation-has been associated with improper gene expression, leading to several disorders. ...
DNA methylation is a vital modification process in the control of genetic information, which contributes to the epigenetics by regulating …
Introduction to the Virtual Issue Alcohol and Epigenetic Regulation: Do the Products of Alcohol Metabolism Drive Epigenetic Control of Gene Expression in Alcohol-Related Disorders?
Vadigepalli R and Hoek JB. Alcohol Clin Exp Res 2018. PMID 29532481 Free PMC article.
Epigenetic regulation, the persistent change in the gene regulatory state following a transient environmental perturbation, has become increasingly prominent in accounting for the consequences of exposure to addictive substances, including alcohol (ethanol). The purpose of this Virtual Issue is to draw attention to some of the recent advances in our understanding of how consumption of alcohol impacts the epigenetic landscape and causes such persistent changes in the regulation of gene expression and cellular function that affect behavior or disease susceptibility well after the alcohol challenge has occurred. ...
Epigenetic regulation, the persistent change in the gene regulatory state following a transient environmental perturbation, ha …
Gene regulation by dietary microRNAs.
Zempleni J, et al. Can J Physiol Pharmacol 2015 - Review. PMID 26222444 Free PMC article.
Recently, that dogma has been challenged in studies suggesting that food-borne miRNAs are bioavailable and affect gene expression in mice and humans. While the evidence in support of this theory may be considered weak for miRNAs that originate in plants, there is compelling evidence to suggest that humans use bovine miRNAs in cow's milk and avian miRNAs in chicken eggs for gene regulation. ...
Recently, that dogma has been challenged in studies suggesting that food-borne miRNAs are bioavailable and affect gene expression
Regulation of gene expression by insulin.
O'Brien RM and Granner DK. Physiol Rev 1996 - Review. PMID 8874496
While insulin has long been known to modulate intracellular metabolism by altering the activity or intracellular location of various enzymes, it is only in the past 10 years that the regulation of gene expression by insulin has been recognized as a major action of this hormone. ...Finally, potential gene expression defects that may contribute to the pathophysiology of non-insulin-dependent diabetes mellitus and hypertriglyceridemia are considered....
While insulin has long been known to modulate intracellular metabolism by altering the activity or intracellular location of various enzymes …
Along the Central Dogma-Controlling Gene Expression with Small Molecules.
Schneider-Poetsch T and Yoshida M. Annu Rev Biochem 2018 - Review. PMID 29727582
As molecular biology progressed and our knowledge of gene control deepened, it became increasingly clear that expression relied on many more levels of regulation. In the process of dissecting mechanisms of gene expression, specific small-molecule inhibitors played an important role and became valuable tools of investigation. ...
As molecular biology progressed and our knowledge of gene control deepened, it became increasingly clear that expression relie …
Effects of the HDAC inhibitor scriptaid on the in vitro development of bovine embryos and on imprinting gene expression levels.
Laguna-Barraza R, et al. Theriogenology 2018. PMID 29353144
This study examines the effects of the histone deacetylation inhibitor scriptaid (SCR) on preimplantation embryo development in vitro and on imprinting gene expression. ...Whether or not such reductions in XIST and imprinting gene expression are beneficial for post implantation development remains to be clarified....
This study examines the effects of the histone deacetylation inhibitor scriptaid (SCR) on preimplantation embryo development in vitro …
169,395 results
Jump to page
Feedback