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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 3
1994 13
1995 10
1996 8
1997 16
1998 10
1999 21
2000 27
2001 25
2002 33
2003 45
2004 43
2005 31
2006 39
2007 32
2008 33
2009 55
2010 48
2011 54
2012 51
2013 39
2014 30
2015 28
2016 29
2017 27
2018 48
2019 16
2020 0
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Page 1
Acoustic reporter genes for noninvasive imaging of microorganisms in mammalian hosts.
Bourdeau RW, et al. Nature 2018. PMID 29300010 Free PMC article.
However, existing methods for imaging cellular location and function, primarily based on optical reporter genes, have limited deep tissue performance owing to light scattering or require radioactive tracers. Here we introduce acoustic reporter genes, which are genetic constructs that allow bacterial gene expression to be visualized in vivo using ultrasound, a widely available inexpensive technique with deep tissue penetration and high spatial resolution. ...
However, existing methods for imaging cellular location and function, primarily based on optical reporter genes, have limited …
The glpD gene is a novel reporter gene for E. coli that is superior to established reporter genes like lacZ and gusA.
Wegener M, et al. J Microbiol Methods 2016. PMID 27794441
The 5'-UTRs of three E. coli genes were chosen and cloned upstream of the new reporter gene glpD as well as the established reporter genes lacZ and gusA. ...Therefore, glpD was found to be a superior novel reporter gene compared to the established reporter genes lacZ and gusA....
The 5'-UTRs of three E. coli genes were chosen and cloned upstream of the new reporter gene glpD as well as the established …
MRI reporter genes.
Gilad AA, et al. J Nucl Med 2008 - Review. PMID 18997049 Free PMC article.
Noninvasive molecular imaging of dynamic processes has benefited tremendously from the use of reporter genes. These genes encode for proteins that emit light, bind radiolabeled probes, or, as covered in this review, modulate MRI contrast. Reporter genes play a pivotal role in monitoring cell trafficking, gene replacement therapy, protein-protein interactions, neuronal plasticity, and embryonic development. ...
Noninvasive molecular imaging of dynamic processes has benefited tremendously from the use of reporter genes. These genes
Pathway reporter genes define molecular phenotypes of human cells.
Zhang JD, et al. BMC Genomics 2015. PMID 25903797 Free PMC article.
We compiled a panel of 917 human pathway reporter genes, representing 154 human signaling and metabolic networks for integrated knowledge- and data-driven understanding of biological processes. ...CONCLUSIONS: A panel of 917 pathway reporter genes is sufficient to describe changes in the molecular phenotype defined by 154 signaling cascades in various human cell types. ...
We compiled a panel of 917 human pathway reporter genes, representing 154 human signaling and metabolic networks for in …
Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo.
Sonzogni O, et al. PLoS Biol 2018. PMID 29924804 Free PMC article.
We report generation of reporter systems driven by either keratin-14 (K14) or keratin-8 (K8) promoter that not only express a fluorescent protein but also an inducible suicide gene. Transgenic mice express the reporter genes in the right cell compartments of mammary gland epithelia and respond to treatment with toxins. ...
We report generation of reporter systems driven by either keratin-14 (K14) or keratin-8 (K8) promoter that not only express a …
New imaging probes to track cell fate: reporter genes in stem cell research.
Jurgielewicz P, et al. Cell Mol Life Sci 2017 - Review. PMID 28674728 Free PMC article.
In recent years, reporter genes have become a popular option for tracking transplanted cells, via various imaging modalities in small mammalian animal models. ...Strengths and limitations of the use of reporter genes in each modality are discussed....
In recent years, reporter genes have become a popular option for tracking transplanted cells, via various imaging modalities i …
Development of Stable Rotavirus Reporter Expression Systems.
Kanai Y, et al. J Virol 2019. PMID 30541830 Free PMC article.
Engineered recombinant viruses expressing reporter genes have been developed for real-time monitoring of replication and for mass screening of antiviral inhibitors. ...The stability of foreign genes within the reporter RV strains harboring a shorter chimeric NSP1-reporter gene was greater than that of those in the original reporter RV strain, independent of the transgene inserted. ...
Engineered recombinant viruses expressing reporter genes have been developed for real-time monitoring of replication an …
Reporter genes facilitating discovery of drugs targeting protozoan parasites.
Dube A, et al. Trends Parasitol 2009 - Review. PMID 19720564
Transfection of protozoan parasites, such as Plasmodium, Leishmania, Trypanosoma and Toxoplasma, with various reporter gene constructs, has revolutionized studies to understand the biology of the host-parasite interactions at the cellular level. ...Furthermore, reporter genes have proved to be an excellent and promising tool for studying disease progression. Here, we review the recent advances made by using reporter genes for in vitro and in vivo drug screening, high-throughput screening, whole-animal non-invasive imaging for parasites and for the study of several aspects of host-parasite interactions....
Transfection of protozoan parasites, such as Plasmodium, Leishmania, Trypanosoma and Toxoplasma, with various reporter gene construct …
Endogenous Locus Reporter Assays.
Liu Y, et al. Methods Mol Biol 2018. PMID 29671270
Traditionally a reporter gene assay is built by cloning an endogenous promoter sequence or synthetic response elements in the regulatory region of a reporter gene to monitor transcriptional activity of a specific biological process (exogenous reporter assay). In contrast, an endogenous locus reporter has a reporter gene inserted in the endogenous gene locus that allows the reporter gene to be expressed under the control of the same regulatory elements as the endogenous gene, thus more accurately reflecting the changes seen in the regulation of the actual gene. ...
Traditionally a reporter gene assay is built by cloning an endogenous promoter sequence or synthetic response elements in the regulat …
Applications of reporter genes.
Lewis JC, et al. Anal Chem 1998 - Review. PMID 9737200
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